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CC BY-NC-ND 4.0 · Indian J Plast Surg 1981; 14(01): 38-42
DOI: 10.1055/s-0043-1778413
Review Article

Chemotherapy For Advanced Oral Cancer

N. N. Khanna
1   Professor, Department of Surgery, Institute of Medical Scicnces, Banaras Hindu University Varanasi-221005, India
,
A. Khanna
2   Lecturer, Department of Surgery, Institute of Medical Scicnces, Banaras Hindu University Varanasi-221005, India
,
G. C. Pant
3   Professor, Department of Radiotheraphy, Institute of Medical Scicnces, Banaras Hindu University Varanasi-221005, India
,
B. Sanyal
4   Reader, Department of Radiotherapy, Institute of Medical Scicnces, Banaras Hindu University Varanasi-221005, India
,
S. Khanna
5   Reader, Department of Pathology, Institute of Medical Scicnces, Banaras Hindu University Varanasi-221005, India
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Summary

A combination of three drugs, cyclophosphamide, methotrexate and 5-Fluorouracil was tried in 50 consecutive cases of advanced oral cancer. The overall response rate was 66%, and the incidence of toxicity 18%. The response was better in primary cases as compared to those who had received prior radiotherapy. However the response was shortlived.



Publication History

Article published online:
19 February 2024

© 2024. Association of Plastic Surgeons of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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