Semin Neurol 2024; 44(01): 074-089
DOI: 10.1055/s-0043-1777423
Review Article

Headache Management in Individuals with Brain Tumor

Ami Cuneo
1   Department of Neurology, University of Washington, Seattle, Washington
,
Natalia Murinova
1   Department of Neurology, University of Washington, Seattle, Washington
› Author Affiliations

Abstract

Headache occurs commonly in individuals diagnosed with cerebral neoplasm. Though the features of a brain tumor-associated headache may vary, a progressive nature of headache and a change in headache phenotype from a prior primary headache disorder often are identified. Pathophysiologic mechanisms proposed for headache associated with brain tumor include headache related to traction on pain-sensitive structures, activation of central and peripheral pain processes, and complications from surgical, chemotherapeutic and/or radiotherapy treatment(s). Optimization of headache management is important for an individual's quality of life. Treatments are based upon patient-specific goals of care and may include tumor-targeted medical and surgical interventions, as well as a multimodal headache treatment approach incorporating acute and preventive medications, nutraceuticals, neuromodulation devices, behavioral interventions, anesthetic nerve blocks, and lifestyles changes.



Publication History

Article published online:
06 January 2024

© 2024. Thieme. All rights reserved.

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