Int J Angiol 2024; 33(01): 050-056
DOI: 10.1055/s-0043-1777257
Rapid Communication

Supervised Exercise Training May Improve Postural Control in Patients with Symptomatic Lower Extremity Peripheral Artery Disease

Francis Degache
1   Institute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
,
Willy Mak
1   Institute of Sport Sciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland
,
Luca Calanca
2   Angiology Department, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland
,
Lucia Mazzolai
2   Angiology Department, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland
,
2   Angiology Department, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland
› Author Affiliations
Funding None.

Abstract

Patients with symptomatic peripheral artery disease (PAD) have been shown to present balance disorders and a history of falling, which are associated with functional and daily life impairments. Although postural control improvement is an important outcome, the benefits of supervised exercise training (SET) on postural control have been seldom investigated in these patients. This article investigates the effects of SET on traditional measures of postural control and on stabilogram-diffusion analysis (SDA) parameters in patients with symptomatic PAD. Patients with symptomatic chronic lower limb claudication were investigated. All subjects who completed the 3-month multimodal SET program and postural control assessment before and after SET were included. Center of pressure trajectory analysis and SDA parameters were investigated using a posturographic platform. Patients were instructed to stand on the platform and maintain balance to their best ability. Treadmill pain-free (PFWD) and maximal (MWD) walking distances were also assessed prior and following SET. Forty-four patients with PAD (65.2 ± 9.8 years, 34% women) were investigated. All postural control parameters were unchanged following SET, except the length of center of pressure displacement as a function of the surface of center of pressure trajectory (LFS), which was significantly increased (before SET: 1.4 ± 0.4; after SET: 1.5 ± 0.5; p = 0.042). PFWD (before SET: 103.5 ± 77.9 m; after SET: 176.8 ± 130.6 m; p ≤ 0.001) and MWD (before SET: 383.6 ± 272.0 m; after SET: 686.4 ± 509.0 m; p ≤ 0.001) significantly improved following SET. The increased LFS suggests a better postural control accuracy following SET in patients with symptomatic PAD.



Publication History

Article published online:
27 November 2023

© 2023. International College of Angiology. This article is published by Thieme.

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  • References

  • 1 Criqui MH, Matsushita K, Aboyans V. et al; American Heart Association Council on Epidemiology and Prevention; Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Radiology and Intervention; Council on Lifestyle and Cardiometabolic Health; Council on Peripheral Vascular Disease; and Stroke Council. Lower extremity peripheral artery disease: contemporary epidemiology, management gaps, and future directions: a scientific statement from the American Heart Association. Circulation 2021; 144 (09) e171-e191
  • 2 McDermott MM, Liu K, Greenland P. et al. Functional decline in peripheral arterial disease: associations with the ankle brachial index and leg symptoms. JAMA 2004; 292 (04) 453-461
  • 3 McDermott MM, Guralnik JM, Tian L. et al. Baseline functional performance predicts the rate of mobility loss in persons with peripheral arterial disease. J Am Coll Cardiol 2007; 50 (10) 974-982
  • 4 Morris DR, Rodriguez AJ, Moxon JV. et al. Association of lower extremity performance with cardiovascular and all-cause mortality in patients with peripheral artery disease: a systematic review and meta-analysis. J Am Heart Assoc 2014; 3 (04) 3
  • 5 Gardner AW, Montgomery PS. Impaired balance and higher prevalence of falls in subjects with intermittent claudication. J Gerontol A Biol Sci Med Sci 2001; 56 (07) M454-M458
  • 6 Gardner AW, Montgomery PS. The relationship between history of falling and physical function in subjects with peripheral arterial disease. Vasc Med 2001; 6 (04) 223-227
  • 7 Gohil RA, Mockford KA, Mazari F. et al. Balance impairment, physical ability, and its link with disease severity in patients with intermittent claudication. Ann Vasc Surg 2013; 27 (01) 68-74
  • 8 Lanzarin M, Parizoto P, Santos GM. Analysis of isokinetic muscle function and postural control in individuals with intermittent claudication. Braz J Phys Ther 2016; 20 (01) 48-57
  • 9 Mockford KA, Mazari FA, Jordan AR, Vanicek N, Chetter IC, Coughlin PA. Computerized dynamic posturography in the objective assessment of balance in patients with intermittent claudication. Ann Vasc Surg 2011; 25 (02) 182-190
  • 10 Alexandrov AV, Frolov AA. Closed-loop and open-loop control of posture and movement during human trunk bending. Biol Cybern 2011; 104 (06) 425-438
  • 11 Caron O, Gelat T, Rougier P, Blanchi JP. A comparative analysis of the center of gravity and center of pressure trajectory path lengths in standing posture: an estimation of active stiffness. J Appl Biomech 2000; 16 (03) 234-247
  • 12 Winter DA, Prince F, Frank JS, Powell C, Zabjek KF. Unified theory regarding A/P and M/L balance in quiet stance. J Neurophysiol 1996; 75 (06) 2334-2343
  • 13 Collins JJ, De Luca CJ. Open-loop and closed-loop control of posture: a random-walk analysis of center-of-pressure trajectories. Exp Brain Res 1993; 95 (02) 308-318
  • 14 Peterka RJ. Postural control model interpretation of stabilogram diffusion analysis. Biol Cybern 2000; 82 (04) 335-343
  • 15 Chung CM, Shin S, Lee Y, Lee DY. Determination of the predictors with the greatest influence on walking in the elderly. Medicina (Kaunas) 2022; 58 (11) 58
  • 16 Treat-Jacobson D, McDermott MM, Bronas UG. et al; American Heart Association Council on Peripheral Vascular Disease; Council on Quality of Care and Outcomes Research; and Council on Cardiovascular and Stroke Nursing. Optimal exercise programs for patients with peripheral artery disease: a scientific statement from the American Heart Association. Circulation 2019; 139 (04) e10-e33
  • 17 Whayne TF, Mukherjee D. Increased exercise favorably modifies coronary artery disease and peripheral arterial disease outcomes. Curr Vasc Pharmacol 2016; 14 (05) 458-465
  • 18 Vieira L, Leite da Cruz J, Razuk M, Rinaldi N. Analysis of postural control and muscle function performance of older adults participating in a multicomponent exercise program in primary health care. Geriatr Gerontol Aging 2022; 16: e0220007
  • 19 Paillard T. Effects of general and local fatigue on postural control: a review. Neurosci Biobehav Rev 2012; 36 (01) 162-176
  • 20 Lanzi S, Boichat J, Calanca L, Aubertin P, Malatesta D, Mazzolai L. Gait changes after supervised exercise training in patients with symptomatic lower extremity peripheral artery disease. Vasc Med 2021; 26 (03) 259-266
  • 21 Lanzi S, Boichat J, Calanca L, Mazzolai L, Malatesta D. Supervised exercise training improves 6 min walking distance and modifies gait pattern during pain-free walking condition in patients with symptomatic lower extremity peripheral artery disease. Sensors (Basel) 2021; 21 (23) 7989
  • 22 Lanzi S, Calanca L, Berchtold A, Mazzolai L. Improvement in 6-minute walking distance after supervised exercise training is related to changes in quality of life in patients with lower extremity peripheral artery disease. J Clin Med 2021; 10 (15) 3330
  • 23 Lanzi S, Pousaz A, Calanca L, Mazzolai L. Sex-based differences in supervised exercise therapy outcomes for symptomatic peripheral artery disease. Vasc Med 2023; 28 (02) 147-149
  • 24 Lanzi S, Pousaz A, Calanca L, Mazzolai L. Sit to stand muscle power is related to functional performance at baseline and after supervised exercise training in patients with lower extremity peripheral artery disease. Eur J Vasc Endovasc Surg 2023; 65 (04) 521-527
  • 25 Aboyans V, Ricco JB, Bartelink MEL. et al; ESC Scientific Document Group. 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries. Endorsed by: the European Stroke Organization (ESO)The Task Force for the Diagnosis and Treatment of Peripheral Arterial Diseases of the European Society of Cardiology (ESC) and of the European Society for Vascular Surgery (ESVS). Eur Heart J 2018; 39 (09) 763-816
  • 26 Fassora M, Calanca L, Jaques C, Mazzolai L, Kayser B, Lanzi S. Intensity-dependent effects of exercise therapy on walking performance and aerobic fitness in symptomatic patients with lower-extremity peripheral artery disease: a systematic review and meta-analysis. Vasc Med 2022; 27 (02) 158-170
  • 27 Degache F, Van Zaen J, Oehen L, Guex K, Trabucchi P, Millet G. Alterations in postural control during the world's most challenging mountain ultra-marathon. PLoS One 2014; 9 (01) e84554
  • 28 Bizzo G, Guillet N, Patat A, Gagey PM. Specifications for building a vertical force platform designed for clinical stabilometry. Med Biol Eng Comput 1985; 23 (05) 474-476
  • 29 Lion A, Spada RS, Bosser G. et al. “Postural first” principle when balance is challenged in elderly people. Int J Neurosci 2014; 124 (08) 558-566
  • 30 Aufauvre V, Kemoun G, Carette P, Bergeal E. Home postural evaluation in the elderly: comparison between fallers and non fallers [in French]. Ann Readapt Med Phys 2005; 48 (04) 165-171
  • 31 Gagey PM, Weber B. Posturologie: Régulation et dérèglements de la station debout. 3ème ed. Paris: Masson; 1999: 29-82
  • 32 Quijoux F, Nicolaï A, Chairi I. et al. A review of center of pressure (COP) variables to quantify standing balance in elderly people: algorithms and open-access code. Physiol Rep 2021; 9 (22) e15067
  • 33 Mockford KA, Gohil RA, Mazari F. et al. Effect of supervised exercise on physical function and balance in patients with intermittent claudication. Br J Surg 2014; 101 (04) 356-362