CC BY 4.0 · SynOpen 2024; 08(03): 138-152
DOI: 10.1055/s-0043-1775379
review

Microwave-Assisted Synthesis of Heterocyclic Scaffolds

Sanjeev Kumar
,
Anand Maurya
,

S.K. is grateful to the Council of Scientific and Industrial Research (CSIR), New Delhi, for the Junior Research Fellowship, file no. 09/0013(15307)2022-EMR-I. A.M. is grateful to the Indian Council of Medical Research (ICMR), New Delhi, for a Senior Research Fellowship (wide letter no. 45/33/2022-BIO/BMS), and A.A. thanks the Banaras Hindu University and Institute of Eminence (IoE no. Dev Scheme no. 6031) for financial support.


Abstract

In recent years, there has been a notable surge in the utilization of microwave energy, leading to the emergence of innovative and groundbreaking methods across various branches of chemistry, including organic synthesis, materials science, heterocyclic chemistry, and medicinal chemistry. This comprehensive literature review delves into the microwave-assisted organic synthesis of specific heterocycles, illuminating its effectiveness in producing diverse molecules with heightened efficiency and selectivity. The review highlights the significant role of microwave irradiation as a potent method for constructing a wide range of compounds. Particular emphasis is placed on the impact of the technique on synthesizing various hybrids such as 1,2,3-triazole hybrids, coumarin hybrids, imidazopyridine hybrids, phenanthridines hybrids, carbene hybrids, and oxazole hybrids. This article is valuable as it offers insights into current synthetic procedures and trends in developing innovative medications utilizing heterocyclic compounds.

1 Introduction

2 Synthesis of 1,2,3-Triazole Hybrids

3 Coumarin Hybrids

4 Imidazo Pyridine Hybrids

5 Phenanthridine Hybrids

6 Carbene Hybrids

7 Oxazole Hybrids

8 Conclusion



Publikationsverlauf

Eingereicht: 29. April 2024

Angenommen nach Revision: 12. Juni 2024

Artikel online veröffentlicht:
03. Juli 2024

© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by/4.0/)

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