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CC BY 4.0 · Chinese medicine and natural products 2023; 03(03): e108-e116
DOI: 10.1055/s-0043-1774414
Review Article

Research Progress of Intestinal Flora and Related Diseases

Yaping Sun
1   Periodical Press, Henan University of Chinese Medicine, Zhengzhou, Henan, China
,
Xindi Zhang
2   College of Pediatric Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan, China
,
Yanli Zhang
3   College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, China
,
Yanpo Si
3   College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, China
,
Bing Cao
3   College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, China
,
Zengfu Shan
3   College of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, Henan, China
› Author Affiliations Funding This work was supported by the Henan University of Chinese Medicine Doctoral Research Initiation Fund Project (RSBSJJ2020-17) and National Key R&D Program - Modernization of Chinese Medicine (2019YFC1708802).
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Abstract

The intestinal tract is an important digestive organ and detoxification organ of the human body, and its circling structure is vividly called the “second brain” of the human body. There are hundreds of millions of bacterium in the intestinal tract. These bacteria live in mutual benefit with the body, provide energy and nutrients for the host and themselves through fermented food, participate in the metabolism of the body, and form a metabolic mode of cometabolism between the host and the symbiotic flora. In addition, intestinal flora can also help the body resist the invasion of pathogens, promote human health, and resist diseases. More and more studies have shown that when the body is subjected to exogenous or endogenous stimuli, the microbial flora in the intestinal will change, and the disturbance of intestinal flora is closely related to the occurrence and development of inflammatory bowel diseases, metabolic diseases, immune system diseases, mental system diseases, and tumors. This article reviews the research progress of the intestinal flora affecting the pathogenesis of various diseases, aiming to provide new references and ideas for the clinical treatment of diseases.

Keywords

intestinal flora - metabolic diseases - bowel diseases - mental system diseases - immune diseases - tumors

CRediT Authorship Contribution Statement

Y.S. was responsible for conceptualization, funding acquisition, and writing-review & editing. X.Z. was responsible for investigation, and writing—original draft. Y.Z. was responsible for supervision. Y.S., B.C. and Z.S. were responsible for investigation.




Publication History

Received: 06 April 2023

Accepted: 24 May 2023

Article published online:
27 September 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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