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Semin intervent Radiol 2023; 40(05): 461-466
DOI: 10.1055/s-0043-1772814
Back to Basics

Transarterial Radioembolization: Overview of Radioembolic Devices

Muhamad Serhal
1   Section of Interventional Radiology, Department of Radiology, Northwestern Memorial Hospital, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois
,
Andrew C. Gordon
1   Section of Interventional Radiology, Department of Radiology, Northwestern Memorial Hospital, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois
,
Daniel B. Brown
2   Division of Interventional Radiology, Vanderbilt University Medical Center, Nashville, Tennessee
,
Beau B. Toskich
3   Division of Interventional Radiology, Mayo Clinic Florida, Jacksonville, Florida
,
Robert J. Lewandowski
1   Section of Interventional Radiology, Department of Radiology, Northwestern Memorial Hospital, Robert H. Lurie Comprehensive Cancer Center, Chicago, Illinois
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Transarterial radioembolization (TARE) is an intra-arterial radiation therapy for patients with primary and secondary hepatic malignancies, and its role outside the liver is evolving. The principle of radioembolization is the transcatheter, intra-arterial delivery of a radioisotope via tumor feeding arteries and treating the perfused tissue with brachytherapy. Hypervascular tumors preferentially receive the radioisotope-carrying microspheres compared to the normal hepatic parenchyma.[1] Because of this, knowledge of hepatic arterial anatomy, principles of transcatheter intra-arterial embolization, and radioisotope (radionuclide or radioactive isotope) characteristics is important to optimize treatment strategies. This article provides a general, back-to-the-basics, overview of available radioembolic devices and an update on radioembolic devices in development.



Publikationsverlauf

Artikel online veröffentlicht:
02. November 2023

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