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CC BY-NC-ND 4.0 · South Asian J Cancer
DOI: 10.1055/s-0043-1771386
Original Article

Telangiectatic Osteosarcoma—A Single-Center Experience

Geetha Narayanan 
1   Department of Medical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India
,
Sugeeth M Thambi
1   Department of Medical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India
,
Jayasree Kattoor
2   Department of Pathology, Regional Cancer Centre, Trivandrum, Kerala, India
,
Bhaskar Subin Sugath
3   Department of Surgical Services, Regional Cancer Centre, Trivandrum, Kerala, India
,
Sreejith G. Nair
1   Department of Medical Oncology, Regional Cancer Centre, Trivandrum, Kerala, India
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Abstract

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Geetha Narayanan

Telangiectatic osteosarcoma is an uncommon subtype of osteosarcoma accounting for less than 4% of all cases of osteosarcoma. It is characterized by distinctive radiographic, pathologic features, and prognostic implications. Radiologically and microscopically, it mimics aneurysmal bone cyst. The objective of this study was to study the clinical profile and treatment outcome of patients with telangiectatic osteosarcoma. Thirteen patients were diagnosed with telangiectatic osteosarcoma in the department of medical oncology at a tertiary cancer center in India during a 12-year period. All patients were above 15 years of age. The median age at presentation was 20 years, males were predominant, and the commonest sites of involvement were lower end of femur and upper end of humerus. Ten patients underwent treatment that consisted of neoadjuvant and/or adjuvant chemotherapy with ifosfamide, doxorubicin, cisplatin regimen and limb sparing surgery or amputation. Currently, eight out of ten patients are alive in remission at a median follow-up of 50 months with survival ranging from 18 to 138 months.

Keywords

telangiectatic - osteosarcoma - bone tumor - chemotherapy - limb salvage surgery


Publication History

Article published online:
28 July 2023

© 2023. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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