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DOI: 10.1055/s-0043-1771170
Chorea secondary to human immunodeficiency virus infection
Coreia secundária à infecção pelo vírus da imunodeficiência humana![](https://www.thieme-connect.de/media/10.1055-s-00054595/202309/lookinside/thumbnails/10-1055-s-0043-1771170_220305-1.jpg)
A 55-year-old woman presented with facial and cervical chorea for 3 months (video). She had a previous history of traumatic right facial nerve palsy but no comorbidities or current medication use. Brain magnetic resonance imaging (MRI) was performed ([Figure 1]). Cerebrospinal fluid analysis was unremarkable. Serum tests were positive for human immunodeficiency virus (HIV) type 1 with 1.877.056 viral copies and T-CD4 lymphocyte count of 35/mm3. Darunavir, ritonavir, dolutegravir, and lamivudine were initiated. After 4 months, chorea showed resolution ([Video 1]). Chorea is a rare manifestation of HIV infection.[1] [2] Differential diagnoses like neurosyphilis, Huntington disease, and Wilson disease should be ruled out.[2]
Video 1 Patient with chorea before treatment for HIV and without chorea after treatment with antiviral therapy.
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Authors' Contributions
AEAF: conceptualization, data curation, formal analysis, investigation, validation, writing – original draft; AM: investigation, writing – original draft; CCDD, HAGT: investigation, supervision. All authors read and approved the final manuscript.
Support
The authors did not receive support from any organization for the submitted work.
Publication History
Received: 11 December 2022
Accepted: 15 March 2023
Article published online:
04 October 2023
© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
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References
- 1 Cardoso F. HIV-related movement disorders: epidemiology, pathogenesis and management. CNS Drugs 2002; 16 (10) 663-668 DOI: 10.2165/00023210-200216100-00002.
- 2 Rajan S, Kaas B, Moukheiber E. Movement Disorders Emergencies. Semin Neurol 2019; 39 (01) 125-136 DOI: 10.1055/s-0038-1677050.