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DOI: 10.1055/s-0043-1770994
Common Causes and Risk Factors for Neonatal Death in NICU in Tobruk Medical Center between July 2018 and July 2019, Libya
Funding None.
Abstract
Background Of the 130 million babies born worldwide each year, an estimated 4 million die during the neonatal period. Of the total global neonatal mortality, 99% occurs in low- and middle-income countries, particularly in Africa and South Asia. The current study was designed to calculate the neonatal mortality rate (NMR), analyze the causes of neonatal deaths, and examine risk factors contributing to neonatal deaths in the neonatal unit of Tobruk Medical Center (TMC).
Methods A case-control study was conducted on 180 newborns divided into two groups admitted to the neonatal intensive care unit (NICU) on the same day of delivery. The first group included 90 newborns who died before day 28 and the second group included 90 newborns who survived until the time of discharge and were selected randomly. The data of the patients were collected from the medical records of newborns admitted to the neonatal unit at TMC between July 2018 and July 2019. All data in this study were statistically analyzed using SPSS 23.0 for Windows (SPSS Inc., Chicago, IL, United States).
Results The NMR among the studied neonates was 12.3 per 1,000 live births, and the death rate was 16.36% per 1,000 admissions. The most common causes of mortality were premature birth (55, 61%), birth asphyxia (18, 20%), and congenital anomalies (10, 11.2%). Less than 50% of the dead patients were on a mechanical ventilator. Premature birth and low birth weight patients are strong predictors of neonatal mortality; normal vaginal delivery had a higher risk of mortality than the other methods of delivery. Gender, maternal blood group, maternal age, and past obstetrical and medical history had no positive correlation with mortality except for antepartum hemorrhage.
Conclusions The study found that the rate of neonatal mortality is similar to that of other hospitals in developing countries and the most common cause of neonatal death was premature birth, and premature birth and low birth weight were the main risk factors for death.


Availability of Data and Materials
Some of the data that support the findings of this study are provided in the charts included in the manuscript. Other data may be available on request from the corresponding author concerning the ethical and legal restrictions, while some patient-sensitive data are not publicly available due to participant privacy/consent restrictions.
Publikationsverlauf
Artikel online veröffentlicht:
19. Juli 2023
© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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References
- 1 World Health Organization. Newborn health epidemiology [Internet]. 2013 . Accessed March 20, 2023 at: http://www.who.int/maternal_child_adolescent/epidemiology/newborn/en/index.html#content and https://apps.who.int/iris/bitstream/handle/10665/259269/WHO-MCA-17.07-eng.pdf;sequence=1
- 2 World Health Organization. Newborn death and illness [Internet]. [Updated September 2011; cited February 2, 2013]. Accessed March 20, 2023 at: http://www.who.int/pmnch/media/press_materials/fs/fs_newborndealth_illness/en/ and https://www.who.int/news-room/fact-sheets/detail/levels-and-trends-in-child-mortality-report-2021
- 3 Shiffman J. Issue attention in global health: the case of newborn survival. Lancet 2010; 375 (9730): 2045-2049
- 4 United Nations Children's Fund. Levels & Trends in Child Mortality. New York: UNICEF; 2012. Accessed March 20, 2023 at: http://www.unicef.org.uk/Documents/Publications/UNICEF_2012_IGME_child_mortality_report.pdf and https://www.who.int/publications/m/item/levels-and-trends-in-child-mortality-report-2021
- 5 World Health Organization. Global Health Observatory (GHO) data: child mortality and causes of death [Online]. . Accessed July 31, 2018 at: http://www.who.int/gho/child_health/mortality/neonatal_text/en/ and accessed March 20, 2023 at: https://www.who.int/data/gho/data/themes/topics/indicator-groups/indicator-group-details/GHO/causes-of-child-death
- 6 Kliegman R, Behrman RE, Jenson HBHB. Neonates. In: Nelson Textbook of Pediatrics. 19th ed. Philadelphia, PA: Elsevier/Saunders; 2011: 519-630
- 7 World Health Organization. Care of the preterm and/or low-birth-weight newborn [Internet]. 2013 . Accessed March 20, 2023 at: http://www.who.int/maternal_child_adolescent/topics/newborn/care_of_preterm/en/ and https://www.who.int/publications-detail-redirect/9789240058262
- 8 Debelew GT, Afework MF, Yalew AW. Determinants and causes of neonatal mortality in Jimma Zone, Southwest Ethiopia: a multilevel analysis of prospective follow up study. PLoS One 2014; 9 (09) e107184
- 9 Li C, Yan H, Zeng L, Dibley MJ, Wang D. Predictors for neonatal death in the rural areas of Shaanxi Province of Northwestern China: a cross-sectional study. BMC Public Health 2015; 15 (01) 387
- 10 Rajab A, Elnasfi SF, Elfakhri A. et al. Characteristics and causes of neonatal mortality in hospitalized cases at Benghazi Children's Hospital 2013–2014. Asian Journal of Pediatric Research 2020; 3: 37-42
- 11 Batieha AM, Khader YS, Berdzuli N. et al. Level, causes and risk factors of neonatal mortality, in Jordan: results of a national prospective study. Matern Child Health J 2016; 20 (05) 1061-1071
- 12 Orsido TT, Asseffa NA, Berheto TM. Predictors of neonatal mortality in neonatal intensive care unit at referral hospital in Southern Ethiopia: a retrospective cohort study. BMC Pregnancy Childbirth 2019; 19 (01) 83
- 13 Moundzika-Kibamba JC, Nakwa FL. Neonatal mortality at Leratong Hospital. SAJCH 2018; 12 (01) 24-28
- 14 Lawn JE, Mwansa-Kambafwile J, Horta BL, Barros FC, Cousens S. “Kangaroo mother care” to prevent neonatal deaths due to preterm birth complications. Int J Epidemiol 2010; 39 (Suppl. 01) i144-i154
- 15 Hoque M, Haaq S, Islam R. Causes of neonatal admissions and deaths at a rural hospital in KwaZulu-Natal, South Africa. South Afr J Epidemiol Infect 2011; 26 (01) 26-29
- 16 Alharam ZM, Elsaeti I, Alferjani M. Neonatal mortality in the neonatal intensive care unit at Benghazi Pediatric Hospital– Libya. Al-Mukhtar Journal of Sciences 2020; 35 (04) 284-293