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CC BY-NC-ND 4.0 · J Lab Physicians 2023; 15(04): 602-607
DOI: 10.1055/s-0043-1770930
Case Report and Review

Edwardsiella tarda Causing Fishbone Injury Cellulitis Leading to Sepsis in a Case of Hematological Malignancy—A Rare Report and Review of Literature

Sushree Sarathi
1   Department of Microbiology, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India
,
Anupam Brahma
2   Department of Hematooncology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
,
Prabodha Kumar Das
2   Department of Hematooncology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
,
Ashoka Mahapatra 
3   Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
,
Bijayini Behera
3   Department of Microbiology, All India Institute of Medical Sciences, Bhubaneswar, Odisha, India
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Abstract

Edwardsiella tarda (E. tarda), a gram-negative bacillus, a member of order Enterobacterales, is typically a fish pathogen frequently isolated from fresh and brackish water environments. It is very rarely implicated in human infections such as gastroenteritis (most common), cellulitis, gas gangrene, hepatobiliary infections, peritonitis, empyema, and meningitis. Bacteremia/sepsis caused by E. tarda can be fatal in humans, although very rare (<5%). To date, very few cases of E. tarda sepsis have been reported worldwide including India. We report a rare case of cellulitis caused by E. tarda following fishbone injury in a patient with underlying hematological malignancy leading to sepsis.

Keywords

Edwardsiella tarda - cellulitis - fishbone injury - hematological malignancy - sepsis


Publication History

Received: 27 March 2023

Accepted: 18 May 2023

Article published online:
13 July 2023

© 2023. The Indian Association of Laboratory Physicians. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Bakirova GH, Alharthy A, Corcione S. et al. Fulminant septic shock due to Edwardsiella tarda infection associated with multiple liver abscesses: a case report and review of the literature. J Med Case Reports 2020; 14 (01) 144
    CrossrefPubMedGoogle Scholar
  • 2 Hirai Y, Asahata-Tago S, Ainoda Y, Fujita T, Kikuchi K. Edwardsiella tarda bacteremia. A rare but fatal water- and foodborne infection: review of the literature and clinical cases from a single centre. Can J Infect Dis Med Microbiol 2015; 26 (06) 313-318
    CrossrefPubMedGoogle Scholar
  • 3 Janda JM, Abbott SL, Kroske-Bystrom S. et al. Pathogenic properties of Edwardsiella species. J Clin Microbiol 1991; 29 (09) 1997-2001
    CrossrefPubMedGoogle Scholar
  • 4 Suzuki K, Yanai M, Hayashi Y, Otsuka H, Kato K, Soma M. Edwardsiella tarda bacteremia with psoas and epidural abscess as a food-borne infection: a case report and literature review. Intern Med 2018; 57 (06) 893-897
    CrossrefPubMedGoogle Scholar
  • 5 Morrisette T, Hewgley WP, Hewgley H. Edwardsiella tarda bacteremia in untreated hepatitis C: alterations in antimicrobial therapy for a pan-susceptible pathogen in a critically ill patient. Am J Ther 2019; 26 (04) e530-e533
    CrossrefPubMedGoogle Scholar
  • 6 Manabe M, Matsumoto Y, Uchida T, Momose D, Sugano Y, Koh KR. [Bacteremia due to Edwardsiella tarda emerging after chemotherapy for recurrent pH-positive acute lymphoblastic leukemia]. Gan To Kagaku Ryoho 2019; 46 (12) 1903-1905
    PubMedGoogle Scholar
  • 7 LeBlond L. Catfish bite case report. Wilderness Environ Med 2019; 30 (03) 291-294
    CrossrefPubMedGoogle Scholar
  • 8 Tonosaki K, Yonenaga K, Mikami T, Mizuno T, Oyama S. Acute cholecystitis, sepsis, and disseminated intravascular coagulation caused by Edwardsiella tarda in an elderly woman. Tokai J Exp Clin Med 2021; 46 (01) 51-53
    PubMedGoogle Scholar
  • 9 Healey KD, Rifai SM, Rifai AO, Edmond M, Baker DS, Rifai K. Edwardsiella tarda: a classic presentation of a rare fatal infection, with possible new background risk factors. Am J Case Rep 2021; 22: e934347
    CrossrefPubMedGoogle Scholar
  • 10 Miyazawa Y, Murakami K, Kizaki Y, Itaya Y, Takai Y, Seki H. Maternal peripartum septic shock caused by intrauterine infection with Edwardsiella tarda: a case report and review of the literature. J Obstet Gynaecol Res 2018; 44 (01) 171-174
    CrossrefPubMedGoogle Scholar
  • 11 Egashira M, Higuchi N, Shichijo A, Egashira T, Takayanagi T. Early-onset Edwardsiella tarda septicemia in an extremely preterm infant. Pediatr Int 2020; 62 (07) 860-861
    CrossrefPubMedGoogle Scholar
  • 12 Peravali R, Muddassir K. A rare but fatal waterborne infection. Am J Med 2021; 134 (05) e329-e330
    CrossrefPubMedGoogle Scholar
  • 13 Ebisawa KF, Nishimura S, Yamamoto S, Ohji G, Iwata K. Mycotic aneurysm caused by Edwardsiella tarda successfully treated with stenting and suppressive antibiotic therapy: a case report and systematic review. Ann Clin Microbiol Antimicrob 2018; 17 (01) 21
    CrossrefPubMedGoogle Scholar
  • 14 Taguchi H, Tamai T, Numata M. et al. Endoscopic ultrasonography-guided transmural drainage of an infected hepatic cyst due to Edwardsiella tarda: a case report. Clin J Gastroenterol 2014; 7 (05) 422-428
    CrossrefPubMedGoogle Scholar
  • 15 Pham K, Wu Y, Turett G. et al. Edwardsiella tarda, a rare human pathogen isolated from a perihepatic abscess: implications of transient versus long term colonization of the gastrointestinal tract. IDCases 2021; 26: e01283
    CrossrefPubMedGoogle Scholar
  • 16 Miyajima S, Yamakawa G, Ohana M. Edwardsiella tarda-associated cholangitis associated with Lemmel syndrome. IDCases 2018; 11: 94-96
    CrossrefPubMedGoogle Scholar
  • 17 Bui A, Cortese C, Libertin CR, Porter II IE. Minimal change disease and subacute interstitial nephritis in association with Edwardsiella tarda gastroenteritis following oyster consumption. IDCases 2021; 25: e01236
    CrossrefPubMedGoogle Scholar
  • 18 Sydorchuk AS, Bogachyk NA, Venhlovska YV. Clinical case of Edwardsiellosis in Ukraine. Wiad Lek 2021; 74 (01) 165-167
    CrossrefPubMedGoogle Scholar
  • 19 Koike M, Doi T, Iba Y, Yuda S. Edwardsiella tarda native valve infective endocarditis in a young and non-immunocompromised host: a case report. Am J Case Rep 2021; 22: e932387
    CrossrefPubMedGoogle Scholar
  • 20 Sundaram K, Ohliger E, Hoban C, Gurd DP. Treatment of an abscess of the leg in a febrile child after incidental trauma from the barb of a freshwater fish: a case report. JBJS Case Connect 2020; 10 (02) e0464
    CrossrefPubMedGoogle Scholar
  • 21 Crosby SN, Snoddy MC, Atkinson CT, Lee DH, Weikert DR. Upper extremity myonecrosis caused by Edwardsiella tarda resulting in transhumeral amputation: case report. J Hand Surg Am 2013; 38 (01) 129-132
    CrossrefPubMedGoogle Scholar
  • 22 Yamamuro T, Fukuhara A, Kang J, Takamatsu J. A case of necrotizing fasciitis following Edwardsiella tarda septicemia with gastroenteritis. J Infect Chemother 2019; 25 (12) 1053-1056
    CrossrefPubMedGoogle Scholar
  • 23 Ota K, Yamanoue H, Aizawa N, Suzuki N, Ota K, Takasu A. Gastric submucosal abscess caused by Edwardsiella tarda infection: a case report. BMC Gastroenterol 2020; 20 (01) 299
    CrossrefPubMedGoogle Scholar
  • 24 Ng QX, Seng C, Chan FZY, Yeo WS. Zoonosis: an unusual case of chronic osteomyelitis. Singapore Med J 2019; 60 (07) 379-381
    CrossrefPubMedGoogle Scholar
  • 25 Tai CH, Kuo SF, Lee CH. Concurrency of splenomegaly and numerous enlarged mesenteric and retroperitoneal lymph nodes in a patient with pelvic inflammatory disease caused by Edwardsiella tarda: mimicking lymphoma. Kaohsiung J Med Sci 2019; 35 (07) 446-447
    CrossrefPubMedGoogle Scholar
  • 26 Koido S, Ohkusa T, Kato K. et al. Edwardsiella tarda superinfection in relapse of ulcerative colitis. J Clin Gastroenterol 2014; 48 (02) 191-193
    CrossrefPubMedGoogle Scholar
  • 27 Verjan N, Hirono I, Aoki T. Genetic loci of major antigenic protein genes of Edwardsiella tarda. Appl Environ Microbiol 2005; 71 (09) 5654-5658
    CrossrefPubMedGoogle Scholar
  • 28 Du M, Chen J, Zhang X, Li A, Li Y, Wang Y. Retention of virulence in a viable but nonculturable Edwardsiella tarda isolate. Appl Environ Microbiol 2007; 73 (04) 1349-1354
    CrossrefPubMedGoogle Scholar
  • 29 Sakai T, Kanai K, Osatomi K, Yoshikoshi K. Identification of a 19.3-kDa protein in MRHA-positive Edwardsiella tarda: putative fimbrial major subunit. FEMS Microbiol Lett 2003; 226 (01) 127-133
    CrossrefPubMedGoogle Scholar
  • 30 Xu T, Su Y, Xu Y. et al. Mutations of flagellar genes fliC12, fliA and flhDC of Edwardsiella tarda attenuated bacterial motility, biofilm formation and virulence to fish. J Appl Microbiol 2014; 116 (02) 236-244
    CrossrefPubMedGoogle Scholar
  • 31 John AM, Prakash JA, Simon EG, Thomas N. Edwardsiella tarda sepsis with multiple liver abscesses in a patient with Cushing's syndrome. Indian J Med Microbiol 2012; 30 (03) 352-354
    CrossrefPubMedGoogle Scholar