Subscribe to RSS
![](/products/assets/desktop/img/oa-logo.png)
DOI: 10.1055/s-0043-1770349
Neuropsychology of epilepsy surgery and theory-based practice: an opinion review
Neuropsicologia da cirurgia de epilepsia e prática teórica: uma revisão de opinião![](https://www.thieme-connect.de/media/10.1055-s-00054595/202309/lookinside/thumbnails/10-1055-s-0043-1770349_220192-1.jpg)
Abstract
The present review attempts to discuss how some of the central concepts from the Lurian corpus of theories are relevant to the modern neuropsychology of epilepsy and epilepsy surgery. Through the lenses of the main Lurian concepts (such as the qualitative syndrome analysis), we discuss the barriers to clinical reasoning imposed by quadrant-based views of the brain, or even atheoretical, statistically-based and data-driven approaches. We further advice towards a systemic view inspired by Luria's clinical work and theorizing, given their importance towards our clinical practice, by contrasting it to the modular views when appropriate. Luria provided theory-guided methods of assessment and rehabilitation of higher cortical functions. Although his work did not specifically address epilepsy, his theory and clinical approaches actually apply to the whole neuropathology spectrum and accounting for the whole panorama of neurocognition. This holistic and systemic approach to the brain is consistent with the network approach of the neuroimaging era. As to epilepsy, the logic of cognitive functions organized into complex functional systems, contrary to modular views of the brain, heralds current knowledge of epilepsy as a network disease, as well as the concept of the functional deficit zone.
Resumo
A presente revisão tenta discutir como alguns dos conceitos centrais do corpus de teorias lurianas são relevantes para a moderna neuropsicologia da epilepsia e cirurgia da epilepsia. Através das lentes dos principais conceitos lurianos (como a análise qualitativa de síndromes), discutimos as barreiras ao raciocínio clínico impostas por visões do cérebro baseadas em quadrantes, ou mesmo abordagens ateóricas, baseadas em estatísticas e orientadas por dados. Aconselhamos ainda uma visão sistêmica inspirada na clínica e na teorização de Luria, dada sua importância para nossa prática clínica, contrastando-a com as visões modulares quando apropriado. Luria forneceu métodos teóricos de avaliação e reabilitação de funções corticais superiores. Embora seu trabalho não abordasse especificamente a epilepsia, sua teoria e abordagens clínicas na verdade se aplicam a todo o espectro da neuropatologia e respondem por todo o panorama da neurocognição. Essa abordagem holística e sistêmica do cérebro é consistente com a abordagem de rede da era da neuroimagem. Quanto à epilepsia, a lógica das funções cognitivas organizadas em sistemas funcionais complexos, ao contrário das visões modulares do cérebro, anuncia o conhecimento atual da epilepsia como uma doença em rede, bem como o conceito de zona de déficit funcional.
Keywords
Neuropsychology - Luria-Nebraska Neuropsychological Battery - Epilepsy - Neurosurgery - Information TheoryPalavras-chave
Neuropsicologia - Bateria Neuropsicológica de Luria-Nebraska - Epilepsia - Neurocirurgia - Teoria da InformaçãoAuthors' Contributions
PP, SG: conceived the presented idea; VK, LM, have focused mainly on bibliographic documentation of the present work; All authors contributed to the final manuscript.
Publication History
Received: 19 August 2022
Accepted: 15 February 2023
Article published online:
04 October 2023
© 2023. Academia Brasileira de Neurologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil
-
References
- 1 Kwan P, Arzimanoglou A, Berg AT. et al. Definition of drug resistant epilepsy: consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies.Berg A. Efficacy of epilepsy surgery: what are the questions today?. Nat Rev Neurol 2011; 7 (06) 311-312
- 2 Téllez-Zenteno JF, Dhar R, Wiebe S. Long-term seizure outcomes following epilepsy surgery: a systematic review and meta-analysis. Brain 2005; 128 (Pt 5): 1188-1198
- 3 Helmstaedter C. Neuropsychological aspects of epilepsy surgery. Epilepsy Behav 2004; 5 (Suppl. 01) S45-S55
- 4 Rosenow F, Lüders H. Presurgical evaluation of epilepsy. Brain 2001; 124 (Pt 9): 1683-1700
- 5 Vogt VL, Äikiä M, Del Barrio A. et al; E-PILEPSY consortium. Current standards of neuropsychological assessment in epilepsy surgery centers across Europe. Epilepsia 2017; 58 (03) 343-355
- 6 Wilson SJ, Baxendale S, Barr W. et al. Indications and expectations for neuropsychological assessment in routine epilepsy care: Report of the ILAE Neuropsychology Task Force, Diagnostic Methods Commission, 2013-2017. Epilepsia 2015; 56 (05) 674-681
- 7 Beaumont JG. Introduction to Neuropsychology. Guilford Press; 2008
- 8 Poldrack RA. Can cognitive processes be inferred from neuroimaging data?. Trends Cogn Sci 2006; 10 (02) 59-63
- 9 Cagigas XE, Bilder RM. Where culture meets neuroimaging: the intersection of Luria's method with modern neuroimaging and cognitive neuroscience research. Luria's Legacy in the 21st Century, 2009: 23-29
- 10 Sawant N, Ravat S, Muzumdar D, Shah U. Is psychiatric assessment essential for better epilepsy surgery outcomes?. Int J Surg 2016; 36 (Pt B): 460-465
- 11 Witt JA, Coras R, Schramm J. et al. Relevance of hippocampal integrity for memory outcome after surgical treatment of mesial temporal lobe epilepsy. J Neurol 2015; 262 (10) 2214-2224
- 12 Kanner AM, Scharfman H, Jette N. et al. Epilepsy as a Network Disorder (1): What can we learn from other network disorders such as autistic spectrum disorder and mood disorders?. Epilepsy Behav 2017; 77: 106-113
- 13 Jones-Gotman M, Smith ML, Risse GL. et al. The contribution of neuropsychology to diagnostic assessment in epilepsy. Epilepsy Behav 2010; 18 (1-2): 3-12
- 14 Chelune GJ, Naugle RI, Lüders H, Awad IA. Prediction of cognitive change as a function of preoperative ability status among temporal lobectomy patients seen at 6-month follow-up. Neurology 1991; 41 (03) 399-404
- 15 Sawrie SM, Martin RC, Gilliam FG, Roth DL, Faught E, Kuzniecky R. Contribution of neuropsychological data to the prediction of temporal lobe epilepsy surgery outcome. Epilepsia 1998; 39 (03) 319-325
- 16 Patrikelis P, Lucci G, Alexoudi A, Verentzioti A, Gatzonis S. Reply to comment on “Indications and expectations for neuropsychological assessment in epilepsy surgery in children and adults”. Epileptic Disord 2020; 22 (03) 353-354
- 17 Jones-Gotman M, Harnadek MC, Kubu CS. Neuropsychological assessment for temporal lobe epilepsy surgery. Can J Neurol Sci 2000; 27 (Suppl. 01) S39-S43 , discussion S50–S52
- 18 Keary TA, Frazier TW, Busch RM, Kubu CS, Iampietro M. Multivariate neuropsychological prediction of seizure lateralization in temporal epilepsy surgical cases. Epilepsia 2007; 48 (08) 1438-1446
- 19 Wechsler D. WMS-III: Wechsler memory scale administration and scoring manual. Psychological Corporation; 1997
- 20 Sawrie SM, Martin RC, Gilliam F, Knowlton R, Faught E, Kuzniecky R. Verbal retention lateralizes patients with unilateral temporal lobe epilepsy and bilateral hippocampal atrophy. Epilepsia 2001; 42 (05) 651-659
- 21 Loring DW, Hermann BP, Lee GP, Drane DL, Meador KJ. The Memory Assessment Scales and lateralized temporal lobe epilepsy. J Clin Psychol 2000; 56 (04) 563-570
- 22 Williams JM. Memory Assessment Scales. Odessa, FL: Psychological Assessment Resources; ;199(1) 1-127
- 23 Wilde N, Strauss E, Chelune GJ. et al. WMS-III performance in patients with temporal lobe epilepsy: group differences and individual classification. J Int Neuropsychol Soc 2001; 7 (07) 881-891
- 24 Chelune GJ, Najm IM. Risk factors associated with postsurgical decrements in memory. Epilepsy Surgery 2000; 2: 497-504
- 25 Patrikelis P, Lucci G, Siatouni A, Verentzioti A, Alexoudi A, Gatzonis S. Potential implications of Luria's work for the neuropsychology of epilepsy and epilepsy surgery: A perspective for re-examination. Epilepsy Behav 2017; 72: 161-172
- 26 Luria AR. The Working Brain, Harmondsworth. Penguin Books; 1973
- 27 Jokeit H, Schacher M. Neuropsychological aspects of type of epilepsy and etiological factors in adults. Epilepsy Behav 2004; 5 (Suppl. 01) S14-S20
- 28 Patrikelis P, Gatzonis S, Siatouni A. et al. Preoperative neuropsychological presentation of patients with refractory frontal lobe epilepsy. Acta Neurochir (Wien) 2016; 158 (06) 1139-1150
- 29 Patrikelis P, Angelakis E, Gatzonis S. Neurocognitive and behavioral functioning in frontal lobe epilepsy: a review. Epilepsy Behav 2009; 14 (01) 19-26
- 30 Lieb JP, Dasheiff RM, Engel Jr J, Genton P, Genton P. Role of the frontal lobes in the propagation of mesial temporal lobe seizures. Epilepsia 1991; 32 (06) 822-837
- 31 Stretton J, Thompson PJ. Frontal lobe function in temporal lobe epilepsy. Epilepsy Res 2012; 98 (01) 1-13
- 32 Milner B. Disorders of learning and memory after temporal lobe lesions in man. Clin Neurosurg 1972; 19 (CN_suppl_1): 421-446
- 33 Kennepohl S, Sziklas V, Garver KE, Wagner DD, Jones-Gotman M. Memory and the medial temporal lobe: hemispheric specialization reconsidered. Neuroimage 2007; 36 (03) 969-978
- 34 Burgess N, Maguire EA, O'Keefe J. The human hippocampus and spatial and episodic memory. Neuron 2002; 35 (04) 625-641
- 35 Law JR, Flanery MA, Wirth S. et al. Functional magnetic resonance imaging activity during the gradual acquisition and expression of paired-associate memory. J Neurosci 2005; 25 (24) 5720-5729
- 36 Nyberg L, Persson J, Habib R. et al. Large scale neurocognitive networks underlying episodic memory. J Cogn Neurosci 2000; 12 (01) 163-173
- 37 Sommer T, Rose M, Gläscher J, Wolbers T, Büchel C. Dissociable contributions within the medial temporal lobe to encoding of object-location associations. Learn Mem 2005; 12 (03) 343-351
- 38 Treyer V, Buck A, Schnider A. Processing content or location: distinct brain activation in a memory task. Hippocampus 2005; 15 (05) 684-689
- 39 Luria AR. Higher Cortical Functions in Man. New York: Consultants Bureau Enterprises. Inc. Diskussion; 1966
- 40 Chelune GJ. Evidence-based research and practice in clinical neuropsychology. Clin Neuropsychol 2010; 24 (03) 454-467
- 41 Barr WB, Nakhutina L. The neuropsychology of epilepsy: an application of Luria's concepts. Luria's legacy in the 21st century, 2009: 103
- 42 Saling MM. Verbal memory in mesial temporal lobe epilepsy: beyond material specificity. Brain 2009; 132 (Pt 3): 570-582
- 43 Cole M, Levitin K, Luria A. The autobiography of Alexander Luria: A dialogue with the making of mind. Psychology Press; 2014
- 44 Silverstein ML, McDonald C, Fogg L. Intelligence and neuropsychological functioning in psychiatric disorders. Arch Clin Neuropsychol 1990; 5 (03) 317-323
- 45 Poldrack RA. Inferring mental states from neuroimaging data: from reverse inference to large-scale decoding. Neuron 2011; 72 (05) 692-697
- 46 Glozman JM. Quantitative and qualitative integration of Lurian procedures. Neuropsychol Rev 1999; 9 (01) 23-32
- 47 Goldberg E. The Executive Control Battery. PsychPress; 1999
- 48 Upton D, Thompson PJ. Epilepsy in the frontal lobes: neuropsychological characteristics. J Epilepsy 1996; 9 (03) 215-222
- 49 Exner C, Boucsein K, Lange C. et al. Neuropsychological performance in frontal lobe epilepsy. Seizure 2002; 11 (01) 20-32
- 50 Goldberg E. Gradiental approach to neocortical functional organization. J Clin Exp Neuropsychol 1989; 11 (04) 489-517
- 51 Goldberg E. Higher cortical functions in humans: The gradiental approach. In: Contemporary neuropsychology and the legacy of Luria. Psychology Press; 2019: 229-276
- 52 Goldberg E, Costa LD. Hemisphere differences in the acquisition and use of descriptive systems. Brain Lang 1981; 14 (01) 144-173
- 53 Fuster JM. Cortex and mind: Unifying cognition. Oxford University Press; 2005
- 54 Halsband U. Bilingual and multilingual language processing. J Physiol Paris 2006; 99 (4-6): 355-369
- 55 Elbert T, Pantev C, Wienbruch C, Rockstroh B, Taub E. Increased cortical representation of the fingers of the left hand in string players. Science 1995; 270 (5234): 305-307
- 56 Landau SM, D'esposito M. Sequence learning in pianists and nonpianists: an fMRI study of motor expertise. Cogn Affect Behav Neurosci 2006; 6 (03) 246-259
- 57 Hanakawa T, Honda M, Okada T, Fukuyama H, Shibasaki H. Neural correlates underlying mental calculation in abacus experts: a functional magnetic resonance imaging study. Neuroimage 2003; 19 (2 Pt 1): 296-307
- 58 Grön G, Schul D, Bretschneider V, Wunderlich AP, Riepe MW. Alike performance during nonverbal episodic learning from diversely imprinted neural networks. Eur J Neurosci 2003; 18 (11) 3112-3120
- 59 Chua HF, Boland JE, Nisbett RE. Cultural variation in eye movements during scene perception. Proc Natl Acad Sci U S A 2005; 102 (35) 12629-12633
- 60 Gutchess AH, Welsh RC, Boduroĝlu A, Park DC. Cultural differences in neural function associated with object processing. Cogn Affect Behav Neurosci 2006; 6 (02) 102-109
- 61 Goh JO, Chee MW, Tan JC. et al. Age and culture modulate object processing and object-scene binding in the ventral visual area. Cogn Affect Behav Neurosci 2007; 7 (01) 44-52
- 62 Han S, Northoff G. Culture-sensitive neural substrates of human cognition: a transcultural neuroimaging approach. Nat Rev Neurosci 2008; 9 (08) 646-654
- 63 Aversi-Ferreira TA, Tamaishi-Watanabe BH, Magri MPF, Aversi-Ferreira RAGMF. Neuropsychology of the temporal lobe: Luria's and contemporary conceptions. Dement Neuropsychol 2019; 13 (03) 251-258
- 64 Rogers BP, Morgan VL, Newton AT, Gore JC. Assessing functional connectivity in the human brain by fMRI. Magn Reson Imaging 2007; 25 (10) 1347-1357
- 65 Sabb FW, Bearden CE, Glahn DC, Parker DS, Freimer N, Bilder RM. A collaborative knowledge base for cognitive phenomics. Mol Psychiatry 2008; 13 (04) 350-360
- 66 Zaytseva Y, Chan RC, Pöppel E, Heinz A. Luria revisited: cognitive research in schizophrenia, past implications and future challenges. Philos Ethics Humanit Med 2015; 10 (01) 4