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DOI: 10.1055/s-0043-1766122
Capsule Endoscopy in Inflammatory Bowel Disease: A Systematic Review
Funding None.![](https://www.thieme-connect.de/media/10.1055-s-00043283/202303/lookinside/thumbnails/10-1055-s-0043-1766122_22120004-1.jpg)
Abstract
The role of video capsule endoscopy (VCE) in inflammatory bowel disease (IBD) has evolved from small bowel to a panenteric evaluation tool over the past two decades. We systematically reviewed the techniques, applications, outcomes, and complications of VCE in IBD. A systematic literature search was performed using PubMed, Embase, and Medline. All relevant original articles involving VCE in IBD were included from 2003 to July 2022. After screening 3,089 citations, finally 201 references were included. The diagnostic yield of VCE in suspected Crohn's disease (CD) was highly variable (6–80%) with excellent sensitivity (77–93%) and specificity (80–89%). The diagnostic yield in known CD was 52 to 88.3% leading to a change in management (26–75%) and disease reclassification with variable retention rates. VCE was superior to small bowel series, computed tomography (CT) and could be better than magnetic resonance enterography (MRE), especially for proximal and superficial lesions. Colon or panenteric VCE has strong correlation to ileo-colonoscopy (IC) and combined magnetic resonance imaging and IC, respectively. The VCE retention rate in CD is higher in known CD which significantly decreases after the negative patency capsule test or CT/MRE. VCE can identify lesions beyond the reach of IC in postoperative CD. Colon Capsule Endoscopy is a noninvasive monitoring tool in ulcerative colitis (UC) having a strong correlation with IC and may uncover small bowel involvement. VCE is specifically useful in IBD-unclassified (IBD-U) which can lead to the diagnosis of CD in 16.7 to 61.5%. Various scoring systems have been established and validated for small bowel CD (Lewis score and capsule endoscopy CD activity index—CECDAI), UC (capsule scoring of UC: Capsule Scoring of Ulcerative Colitis), panenteric evaluation (Capsule Endoscopy Crohn's Disease Activity Index, Elaikim score), and flare prediction (APEX score). Technological advances include double head, three-dimensional reconstruction, sampling system, panoramic view (344 and 360 degree lateral), and panenteric capsule. Artificial intelligence and software like TOP100 and Quickview can help reduce capsule reading time with excellent sensitivity and specificity. VCE in IBD has widespread application in suspected and known small bowel CD, monitoring of UC, postoperative CD, IBD-U, and for panenteric evaluation. Patency capsule testing helps to reduce retention rates significantly. Artificial intelligence and technical advances can help evolve this novel technology.
Keywords
video capsule endoscopy - Crohn's disease - ulcerative colitis - inflammatory bowel disease - patency capsuleAuthors' Contribution
P.P. was responsible for conceptualization, literature review and writing original draft, and illustrations. P.P., R.G., and P.M.R. were responsible for images. M.T., R.B., R.G., P.M.R., and D.N.R. were responsible for proof reading and critical review. M.T., P.P., R.B., R.G., P.M.R., and D.N.R. were responsible for approving final manuscript.
Publikationsverlauf
Artikel online veröffentlicht:
23. Oktober 2023
© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
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References
- 1 Buisson A, Gonzalez F, Poullenot F. et al; ACCEPT study group. Comparative acceptability and perceived clinical utility of monitoring tools: a nationwide survey of patients with inflammatory bowel disease. Inflamm Bowel Dis 2017; 23 (08) 1425-1433
- 2 Goodsall TM, Noy R, Nguyen TM, Costello SP, Jairath V, Bryant RV. Systematic review: patient perceptions of monitoring tools in inflammatory bowel disease. J Can Assoc Gastroenterol 2020; 4 (02) e31-e41
- 3 Yamada K, Nakamura M, Yamamura T. et al. Diagnostic yield of colon capsule endoscopy for Crohn's disease lesions in the whole gastrointestinal tract. BMC Gastroenterol 2021; 21 (01) 75
- 4 Eliakim R, Magro F. Imaging techniques in IBD and their role in follow-up and surveillance. Nat Rev Gastroenterol Hepatol 2014; 11 (12) 722-736
- 5 Yau YY, Wasinger VC, Hirten RP. et al. Current trends in IBD-development of mucosal-based biomarkers and a novel minimally invasive recoverable sampling system. Inflamm Bowel Dis 2021; 27 (Suppl. 02) S17-S24
- 6 Pal P, Vishwakarma P, Singh AP. et al. Diagnostic yield and technical performance of the novel motorized spiral enteroscopy compared with single-balloon enteroscopy in suspected Crohn's disease: a prospective study (with video). Gastrointest Endosc 2022; (e-pub ahead of print). DOI: 10.1016/j.gie.2022.10.017.
- 7 Fireman Z, Mahajna E, Broide E. et al. Diagnosing small bowel Crohn's disease with wireless capsule endoscopy. Gut 2003; 52 (03) 390-392
- 8 Herrerías JM, Caunedo A, Rodríguez-Téllez M, Pellicer F, Herrerías Jr JM. Capsule endoscopy in patients with suspected Crohn's disease and negative endoscopy. Endoscopy 2003; 35 (07) 564-568
- 9 Argüelles-Arias F, Caunedo A, Romero J. et al. The value of capsule endoscopy in pediatric patients with a suspicion of Crohn's disease. Endoscopy 2004; 36 (10) 869-873
- 10 Ge ZZ, Hu YB, Xiao SD. Capsule endoscopy in diagnosis of small bowel Crohn's disease. World J Gastroenterol 2004; 10 (09) 1349-1352
- 11 Mow WS, Lo SK, Targan SR. et al. Initial experience with wireless capsule enteroscopy in the diagnosis and management of inflammatory bowel disease. Clin Gastroenterol Hepatol 2004; 2 (01) 31-40
- 12 De Bona M, Bellumat A, Cian E, Valiante F, Moschini A, De Boni M. Capsule endoscopy findings in patients with suspected Crohn's disease and biochemical markers of inflammation. Dig Liver Dis 2006; 38 (05) 331-335
- 13 van Tuyl SA, Van Noorden JT, Kuipers EJ, Stolk MF. Results of videocapsule endoscopy in 250 patients with suspected small bowel pathology. Dig Dis Sci 2006; 51 (05) 900-905
- 14 Girelli CM, Porta P, Malacrida V, Barzaghi F, Rocca F. Clinical outcome of patients examined by capsule endoscopy for suspected small bowel Crohn's disease. Dig Liver Dis 2007; 39 (02) 148-154
- 15 May A, Manner H, Schneider M, Ipsen A, Ell C. Prospective multicenter trial of capsule endoscopy in patients with chronic abdominal pain, diarrhea and other signs and symptoms (CEDAP-Plus Study). Endoscopy 2007; 39 (07) 606-612
- 16 van Tuyl SA, van Noorden JT, Stolk MF, Kuipers EJ. Clinical consequences of videocapsule endoscopy in GI bleeding and Crohn's disease. Gastrointest Endosc 2007; 66 (06) 1164-1170
- 17 Moy L, Levine J. Capsule endoscopy in the evaluation of patients with unexplained growth failure. J Pediatr Gastroenterol Nutr 2009; 48 (05) 647-650
- 18 Tukey M, Pleskow D, Legnani P, Cheifetz AS, Moss AC. The utility of capsule endoscopy in patients with suspected Crohn's disease. Am J Gastroenterol 2009; 104 (11) 2734-2739
- 19 Figueiredo P, Almeida N, Lopes S, Duque G, Freire P, Lérias C. et al. Small-bowel capsule endoscopy in patients with suspected Crohn's disease-diagnostic value and complications. Diagn Ther Endosc 2010; (e-pub ahead of print). DOI: 10.1155/2010/101284.
- 20 Nuutinen H, Kolho KL, Salminen P. et al. Capsule endoscopy in pediatric patients: technique and results in our first 100 consecutive children. Scand J Gastroenterol 2011; 46 (09) 1138-1143
- 21 Adler SN, Yoav M, Eitan S, Yehuda C, Eliakim R. Does capsule endoscopy have an added value in patients with perianal disease and a negative work up for Crohn's disease?. World J Gastrointest Endosc 2012; 4 (05) 185-188
- 22 Cohen SA, Ephrath H, Lewis JD. et al. Pediatric capsule endoscopy: review of the small bowel and patency capsules. J Pediatr Gastroenterol Nutr 2012; 54 (03) 409-413
- 23 Gralnek IM, Cohen SA, Ephrath H. et al. Small bowel capsule endoscopy impacts diagnosis and management of pediatric inflammatory bowel disease: a prospective study. Dig Dis Sci 2012; 57 (02) 465-471
- 24 Kalla R, McAlindon ME, Drew K, Sidhu R. Clinical utility of capsule endoscopy in patients with Crohn's disease and inflammatory bowel disease unclassified. Eur J Gastroenterol Hepatol 2013; 25 (06) 706-713
- 25 Min SB, Le-Carlson M, Singh N. et al. Video capsule endoscopy impacts decision making in pediatric IBD: a single tertiary care center experience. Inflamm Bowel Dis 2013; 19 (10) 2139-2145
- 26 Esaki M, Matsumoto T, Watanabe K. et al. Use of capsule endoscopy in patients with Crohn's disease in Japan: a multicenter survey. J Gastroenterol Hepatol 2014; 29 (01) 96-101
- 27 Egnatios J, Kaushal K, Kalmaz D, Zarrinpar A. Video capsule endoscopy in patients with chronic abdominal pain with or without associated symptoms: a retrospective study. PLoS One 2015; 10 (04) e0126509
- 28 Lee HS, Lim YJ. Capsule endoscopy for ileitis with potential involvement of other sections of the small bowel. Gastroenterol Res Pract 2016; 2016: 9804783
- 29 Mitselos IV, Christodoulou DK, Katsanos KH. et al. The role of small bowel capsule endoscopy and ileocolonoscopy in patients with nonspecific but suggestive symptoms of Crohn's disease. Eur J Gastroenterol Hepatol 2016; 28 (08) 882-889
- 30 Song HJ, Moon JS, Jeon SR. et al; Korean Gut Image Study Group. Diagnostic yield and clinical impact of video capsule endoscopy in patients with chronic diarrhea: A Korean Multicenter CAPENTRY Study. Gut Liver 2017; 11 (02) 253-260
- 31 Eliakim R, Spada C, Lapidus A. et al. Evaluation of a new pan-enteric video capsule endoscopy system in patients with suspected or established inflammatory bowel disease—feasibility study. Endosc Int Open 2018; 6 (10) E1235-E1246
- 32 Huang L, Huang Z, Tai Y, Wang P, Hu B, Tang C. The small bowel diseases detected by capsule endoscopy in patients with chronic abdominal pain: a retrospective study. Medicine (Baltimore) 2018; 97 (08) e0025
- 33 de Sousa Magalhães R, Rosa B, Marques M. et al. How should we select suspected Crohn's disease patients for capsule enteroscopy?. Scand J Gastroenterol 2019; 54 (08) 991-997
- 34 Wu J, Huang Z, Wang Y. et al. Clinical features of capsule endoscopy in 825 children: a single-center, retrospective cohort study. Medicine (Baltimore) 2020; 99 (43) e22864
- 35 Tai FWD, Ellul P, Elosua A. et al. Panenteric capsule endoscopy identifies proximal small bowel disease guiding upstaging and treatment intensification in Crohn's disease: a European multicentre observational cohort study. United European Gastroenterol J 2021; 9 (02) 248-255
- 36 Brodersen JB, Andersen KW, Jensen MD. Adherence to the bowel cleansing regimen for pan-enteric capsule endoscopy in patients with suspected Crohn's disease and factors affecting the image quality. Scand J Gastroenterol 2022; 57 (04) 501-506
- 37 Elosua González A, Nantes Castillejo Ó, Fernández-Urién Sainz I, López-García A, Murcia Pomares Ó, Zabana Y. en nombre de Grupo Joven GETECCU y del Grupo Joven de AEG. Use of capsule endoscopy in inflammatory bowel disease in clinical practice in Spain. Results from a national survey. Gastroenterol Hepatol 2021; 44 (10) 696-703
- 38 Dionisio PM, Gurudu SR, Leighton JA. et al. Capsule endoscopy has a significantly higher diagnostic yield in patients with suspected and established small-bowel Crohn's disease: a meta-analysis. Am J Gastroenterol 2010; 105 (06) 1240-1248 , quiz 1249
- 39 Choi M, Lim S, Choi MG, Shim KN, Lee SH. Effectiveness of capsule endoscopy compared with other diagnostic modalities in patients with small bowel Crohn's disease: a meta-analysis. Gut Liver 2017; 11 (01) 62-72
- 40 Sihag S, Tan B, Semenov S. et al. Development of significant disease in a cohort of patients with non-specific enteritis on capsule endoscopy: clinical suspicion and a high base line Lewis score are predictive of Crohn's disease. BMC Gastroenterol 2020; 20 (01) 341
- 41 Rana SS, Sharma V, Sharma R, Nada R, Gupta R, Bhasin DK. Capsule endoscopy in small bowel Crohn's disease and tuberculosis. Trop Doct 2017; 47 (02) 113-118
- 42 Fidder HH, Nadler M, Lahat A. et al. The utility of capsule endoscopy in the diagnosis of Crohn's disease based on patient's symptoms. J Clin Gastroenterol 2007; 41 (04) 384-387
- 43 Xue M, Chen X, Shi L, Si J, Wang L, Chen S. Small-bowel capsule endoscopy in patients with unexplained chronic abdominal pain: a systematic review. Gastrointest Endosc 2015; 81 (01) 186-193
- 44 Rodrigues-Pinto E, Cardoso H, Rosa B. et al. Development of a predictive model of Crohn's disease proximal small bowel involvement in capsule endoscopy evaluation. Endosc Int Open 2016; 4 (06) E631-E636
- 45 Valle J, Alcántara M, Pérez-Grueso MJ. et al. Clinical features of patients with negative results from traditional diagnostic work-up and Crohn's disease findings from capsule endoscopy. J Clin Gastroenterol 2006; 40 (08) 692-696
- 46 Hale MF, Drew K, McAlindon ME, Sidhu R. The diagnostic accuracy of faecal calprotectin and small bowel capsule endoscopy and their correlation in suspected isolated small bowel Crohn's disease. Eur J Gastroenterol Hepatol 2016; 28 (10) 1145-1150
- 47 Aggarwal V, Day AS, Connor S. et al. Role of capsule endoscopy and fecal biomarkers in small-bowel Crohn's disease to assess remission and predict relapse. Gastrointest Endosc 2017; 86 (06) 1070-1078
- 48 Sipponen T, Haapamäki J, Savilahti E. et al. Fecal calprotectin and S100A12 have low utility in prediction of small bowel Crohn's disease detected by wireless capsule endoscopy. Scand J Gastroenterol 2012; 47 (07) 778-784
- 49 Yang L, Ge ZZ, Gao YJ. et al. Assessment of capsule endoscopy scoring index, clinical disease activity, and C-reactive protein in small bowel Crohn's disease. J Gastroenterol Hepatol 2013; 28 (05) 829-833
- 50 Höög CM, Bark LÅ, Broström O, Sjöqvist U. Capsule endoscopic findings correlate with fecal calprotectin and C-reactive protein in patients with suspected small-bowel Crohn's disease. Scand J Gastroenterol 2014; 49 (09) 1084-1090
- 51 Egea Valenzuela J, Pereñíguez López A, Pérez Fernández V, Alberca de Las Parras F, Carballo Álvarez F. Fecal calprotectin and C-reactive protein are associated with positive findings in capsule endoscopy in suspected small bowel Crohn's disease. Rev Esp Enferm Dig 2016; 108 (07) 394-400
- 52 Kopylov U, Yung DE, Engel T. et al. Fecal calprotectin for the prediction of small-bowel Crohn's disease by capsule endoscopy: a systematic review and meta-analysis. Eur J Gastroenterol Hepatol 2016; 28 (10) 1137-1144
- 53 Koulaouzidis A, Sipponen T, Nemeth A. et al. Association between fecal calprotectin levels and small-bowel inflammation score in capsule endoscopy: a multicenter retrospective study. Dig Dis Sci 2016; 61 (07) 2033-2040
- 54 Bar-Gil Shitrit A, Koslowsky B, Livovsky DM. et al. A prospective study of fecal calprotectin and lactoferrin as predictors of small bowel Crohn's disease in patients undergoing capsule endoscopy. Scand J Gastroenterol 2017; 52 (03) 328-333
- 55 Mitselos IV, Katsanos KH, Tatsioni A. et al. Association of clinical and inflammatory markers with small bowel capsule endoscopy findings in Crohn's disease. Eur J Gastroenterol Hepatol 2018; 30 (08) 861-867
- 56 Monteiro S, Barbosa M, Cúrdia Gonçalves T. et al. Fecal calprotectin as a selection tool for small bowel capsule endoscopy in suspected Crohn's disease. Inflamm Bowel Dis 2018; 24 (09) 2033-2038
- 57 Yousuf H, Aleem U, Egan R, Maheshwari P, Mohamad J, McNamara D. Elevated faecal calprotectin levels are a reliable non-invasive screening tool for small bowel Crohn's disease in patients undergoing capsule endoscopy. Dig Dis 2018; 36 (03) 202-208
- 58 Omori T, Kambayashi H, Murasugi S. et al. Comparison of Lewis Score and Capsule Endoscopy Crohn's Disease Activity Index in patients with Crohn's Disease. Dig Dis Sci 2020; 65 (04) 1180-1188
- 59 Jung ES, Lee SP, Kae SH, Kim JH, Kim HS, Jang HJ. Diagnostic accuracy of fecal calprotectin for the detection of small bowel Crohn's disease through capsule endoscopy: an updated meta-analysis and systematic review. Gut Liver 2021; 15 (05) 732-741
- 60 Xiang B, Dong Z, Dai C. The diagnostic and predictive value of fecal calprotectin and capsule endoscopy for small-bowel Crohn's disease: a systematic review and meta-analysis. Rev Esp Enferm Dig 2021; 113 (03) 193-201
- 61 Egea-Valenzuela J, González Suárez B, Sierra Bernal C. et al. Development and validation of a scoring index to predict the presence of lesions in capsule endoscopy in patients with suspected Crohn's disease of the small bowel: a Spanish multicenter study. Eur J Gastroenterol Hepatol 2018; 30 (05) 499-505
- 62 Rosa B, Moreira MJ, Rebelo A, Cotter J. Lewis Score: a useful clinical tool for patients with suspected Crohn's Disease submitted to capsule endoscopy. J Crohn's Colitis 2012; 6 (06) 692-697
- 63 Robertson AR, Yung DE, Arnott ID, Plevris JN, Koulaouzidis A. Capsule endoscopy in suspected small bowel Crohn's disease—is it worth repeating a negative study?. Dig Liver Dis 2019; 51 (01) 174-176
- 64 Teshima CW, Goodman KJ, El-Kalla M. et al. Increased intestinal permeability in relatives of patients with Crohn's disease is not associated with small bowel ulcerations. Clin Gastroenterol Hepatol 2017; 15 (09) 1413-1418.e1
- 65 Taylor KM, Hanscombe KB, Prescott NJ. et al. Genetic and inflammatory biomarkers classify small intestine inflammation in asymptomatic first-degree relatives of patients with Crohn's disease. Clin Gastroenterol Hepatol 2020; 18 (04) 908-916.e13
- 66 Eliakim R, Karban A, Markovits D. et al. Comparison of capsule endoscopy with ileocolonoscopy for detecting small-bowel lesions in patients with seronegative spondyloarthropathies. Endoscopy 2005; 37 (12) 1165-1169
- 67 Gheorghe A, Zahiu DCM, Voiosu TA, Mateescu BR, Voiosu MR, Rimbaş M. Is the use of AGILE patency capsule prior to videocapsule endoscopy useful in all patients with spondyloarthritis?. Rom J Intern Med 2017; 55 (02) 82-88
- 68 Kopylov U, Starr M, Watts C, Dionne S, Girardin M, Seidman EG. Detection of Crohn disease in patients with spondyloarthropathy: the SpACE capsule study. J Rheumatol 2018; 45 (04) 498-505
- 69 Taddio A, Simonini G, Lionetti P. et al. Usefulness of wireless capsule endoscopy for detecting inflammatory bowel disease in children presenting with arthropathy. Eur J Pediatr 2011; 170 (10) 1343-1347
- 70 Park CH, Kim JO, Choi MG. et al. Utility of capsule endoscopy for the classification of Crohn's disease: a multicenter study in Korea. Dig Dis Sci 2007; 52 (06) 1405-1409
- 71 Cohen SA, Gralnek IM, Ephrath H. et al. Capsule endoscopy may reclassify pediatric inflammatory bowel disease: a historical analysis. J Pediatr Gastroenterol Nutr 2008; 47 (01) 31-36
- 72 Lorenzo-Zúñiga V, de Vega VM, Domènech E, Cabré E, Mañosa M, Boix J. Impact of capsule endoscopy findings in the management of Crohn's Disease. Dig Dis Sci 2010; 55 (02) 411-414
- 73 Mehdizadeh S, Chen GC, Barkodar L. et al. Capsule endoscopy in patients with Crohn's disease: diagnostic yield and safety. Gastrointest Endosc 2010; 71 (01) 121-127
- 74 Petruzziello C, Onali S, Calabrese E. et al. Wireless capsule endoscopy and proximal small bowel lesions in Crohn's disease. World J Gastroenterol 2010; 16 (26) 3299-3304
- 75 Di Nardo G, Oliva S, Ferrari F. et al. Usefulness of wireless capsule endoscopy in paediatric inflammatory bowel disease. Dig Liver Dis 2011; 43 (03) 220-224
- 76 Long MD, Barnes E, Isaacs K, Morgan D, Herfarth HH. Impact of capsule endoscopy on management of inflammatory bowel disease: a single tertiary care center experience. Inflamm Bowel Dis 2011; 17 (09) 1855-1862
- 77 Dussault C, Gower-Rousseau C, Salleron J. et al. Small bowel capsule endoscopy for management of Crohn's disease: a retrospective tertiary care centre experience. Dig Liver Dis 2013; 45 (07) 558-561
- 78 Flamant M, Trang C, Maillard O. et al. The prevalence and outcome of jejunal lesions visualized by small bowel capsule endoscopy in Crohn's disease. Inflamm Bowel Dis 2013; 19 (07) 1390-1396
- 79 Cotter J, Dias de Castro F, Moreira MJ, Rosa B. Tailoring Crohn's disease treatment: the impact of small bowel capsule endoscopy. J Crohn's Colitis 2014; 8 (12) 1610-1615
- 80 Niv E, Fishman S, Kachman H, Arnon R, Dotan I. Sequential capsule endoscopy of the small bowel for follow-up of patients with known Crohn's disease. J Crohn's Colitis 2014; 8 (12) 1616-1623
- 81 Kopylov U, Ben-Horin S, Seidman EG, Eliakim R. Video capsule endoscopy of the small bowel for monitoring of Crohn's disease. Inflamm Bowel Dis 2015; 21 (11) 2726-2735
- 82 Kopylov U, Yablecovitch D, Lahat A. et al. Detection of small bowel mucosal healing and deep remission in patients with known small bowel Crohn's disease using biomarkers, capsule endoscopy, and imaging. Am J Gastroenterol 2015; 110 (09) 1316-1323
- 83 Santos-Antunes J, Cardoso H, Lopes S, Marques M, Nunes AC, Macedo G. Capsule enteroscopy is useful for the therapeutic management of Crohn's disease. World J Gastroenterol 2015; 21 (44) 12660-12666
- 84 Greener T, Klang E, Yablecovitch D. et al; Israeli IBD Research Nucleus (IIRN). The impact of magnetic resonance enterography and capsule endoscopy on the re-classification of disease in patients with known Crohn's disease: a prospective Israeli IBD Research Nucleus (IIRN) Study. J Crohn's Colitis 2016; 10 (05) 525-531
- 85 Hansel SL, McCurdy JD, Barlow JM. et al. Clinical benefit of capsule endoscopy in Crohn's disease: impact on patient management and prevalence of proximal small bowel involvement. Inflamm Bowel Dis 2018; 24 (07) 1582-1588
- 86 Melmed GY, Dubinsky MC, Rubin DT. et al. Utility of video capsule endoscopy for longitudinal monitoring of Crohn's disease activity in the small bowel: a prospective study. Gastrointest Endosc 2018; 88 (06) 947-955.e2
- 87 Oliva S, Aloi M, Viola F. et al. A treat to target strategy using panenteric capsule endoscopy in pediatric patients with Crohn's disease. Clin Gastroenterol Hepatol 2019; 17 (10) 2060-2067.e1
- 88 Elosua A, Rullan M, Rubio S. et al. Does capsule endoscopy impact clinical management in established Crohn's disease?. Dig Liver Dis 2022; 54 (01) 118-124
- 89 Tsibouris P, Periklis A, Chrissostomos K. et al. When Crohn's disease is in remission, more patients complete capsule endoscopy study but less lesions are identified. Saudi J Gastroenterol 2013; 19 (02) 63-68
- 90 Hall BJ, Holleran GE, Smith SM, Mahmud N, McNamara DA. A prospective 12-week mucosal healing assessment of small bowel Crohn's disease as detected by capsule endoscopy. Eur J Gastroenterol Hepatol 2014; 26 (11) 1253-1259
- 91 Hall B, Holleran G, Chin JL. et al. A prospective 52 week mucosal healing assessment of small bowel Crohn's disease as detected by capsule endoscopy. J Crohn's Colitis 2014; 8 (12) 1601-1609
- 92 Eliakim R, Fischer D, Suissa A. et al. Wireless capsule video endoscopy is a superior diagnostic tool in comparison to barium follow-through and computerized tomography in patients with suspected Crohn's disease. Eur J Gastroenterol Hepatol 2003; 15 (04) 363-367
- 93 Eliakim R, Suissa A, Yassin K, Katz D, Fischer D. Wireless capsule video endoscopy compared to barium follow-through and computerised tomography in patients with suspected Crohn's disease—final report. Dig Liver Dis 2004; 36 (08) 519-522
- 94 Hara AK, Leighton JA, Heigh RI. et al. Crohn disease of the small bowel: preliminary comparison among CT enterography, capsule endoscopy, small-bowel follow-through, and ileoscopy. Radiology 2006; 238 (01) 128-134
- 95 Casciani E, Masselli G, Di Nardo G. et al. MR enterography versus capsule endoscopy in paediatric patients with suspected Crohn's disease. Eur Radiol 2011; 21 (04) 823-831
- 96 Petruzziello C, Calabrese E, Onali S. et al. Small bowel capsule endoscopy vs conventional techniques in patients with symptoms highly compatible with Crohn's disease. J Crohn's Colitis 2011; 5 (02) 139-147
- 97 Leighton JA, Gralnek IM, Cohen SA. et al. Capsule endoscopy is superior to small-bowel follow-through and equivalent to ileocolonoscopy in suspected Crohn's disease. Clin Gastroenterol Hepatol 2014; 12 (04) 609-615
- 98 Carter D, Katz LH, Bardan E. et al. The accuracy of intestinal ultrasound compared with small bowel capsule endoscopy in assessment of suspected Crohn's disease in patients with negative ileocolonoscopy. Therap Adv Gastroenterol 2018; 11: 1756284818765908
- 99 Marmo R, Rotondano G, Piscopo R. et al. Capsule endoscopy versus enteroclysis in the detection of small-bowel involvement in Crohn's disease: a prospective trial. Clin Gastroenterol Hepatol 2005; 3 (08) 772-776
- 100 Voderholzer WA, Beinhoelzl J, Rogalla P. et al. Small bowel involvement in Crohn's disease: a prospective comparison of wireless capsule endoscopy and computed tomography enteroclysis. Gut 2005; 54 (03) 369-373
- 101 D'Haens G, Löwenberg M, Samaan MA. et al. Safety and feasibility of using the Second-Generation Pillcam Colon Capsule to assess active colonic Crohn's disease. Clin Gastroenterol Hepatol 2015; 13 (08) 1480-6.e3
- 102 Oliva S, Cucchiara S, Civitelli F. et al. Colon capsule endoscopy compared with other modalities in the evaluation of pediatric Crohn's disease of the small bowel and colon. Gastrointest Endosc 2016; 83 (05) 975-983
- 103 Leighton JA, Helper DJ, Gralnek IM. et al. Comparing diagnostic yield of a novel pan-enteric video capsule endoscope with ileocolonoscopy in patients with active Crohn's disease: a feasibility study. Gastrointest Endosc 2017; 85 (01) 196-205.e1
- 104 Ben-Horin S, Lahat A, Amitai MM. et al; Israeli IBD Research Nucleus (IIRN). Assessment of small bowel mucosal healing by video capsule endoscopy for the prediction of short-term and long-term risk of Crohn's disease flare: a prospective cohort study. Lancet Gastroenterol Hepatol 2019; 4 (07) 519-528
- 105 Hijaz NM, Attard TM, Colombo JM, Mardis NJ, Friesen CA. Comparison of the use of wireless capsule endoscopy with magnetic resonance enterography in children with inflammatory bowel disease. World J Gastroenterol 2019; 25 (28) 3808-3822
- 106 Bruining DH, Oliva S, Fleisher MR, Fischer M, Fletcher JG. BLINK study group. Panenteric capsule endoscopy versus ileocolonoscopy plus magnetic resonance enterography in Crohn's disease: a multicentre, prospective study. BMJ Open Gastroenterol 2020; 7 (01) e000365
- 107 Papalia I, Tjandra D, Quah S. et al. Colon capsule endoscopy in the assessment of mucosal healing in Crohn's disease. Inflamm Bowel Dis 2021; 27 (Supplement_2): S25-S32
- 108 Albert JG, Martiny F, Krummenerl A. et al. Diagnosis of small bowel Crohn's disease: a prospective comparison of capsule endoscopy with magnetic resonance imaging and fluoroscopic enteroclysis. Gut 2005; 54 (12) 1721-1727
- 109 Chong AK, Taylor A, Miller A, Hennessy O, Connell W, Desmond P. Capsule endoscopy vs. push enteroscopy and enteroclysis in suspected small-bowel Crohn's disease. Gastrointest Endosc 2005; 61 (02) 255-261
- 110 Dubcenco E, Jeejeebhoy KN, Petroniene R. et al. Capsule endoscopy findings in patients with established and suspected small-bowel Crohn's disease: correlation with radiologic, endoscopic, and histologic findings. Gastrointest Endosc 2005; 62 (04) 538-544
- 111 Efthymiou A, Viazis N, Mantzaris G. et al. Does clinical response correlate with mucosal healing in patients with Crohn's disease of the small bowel? A prospective, case-series study using wireless capsule endoscopy. Inflamm Bowel Dis 2008; 14 (11) 1542-1547
- 112 Solem CA, Loftus Jr EV, Fletcher JG. et al. Small-bowel imaging in Crohn's disease: a prospective, blinded, 4-way comparison trial. Gastrointest Endosc 2008; 68 (02) 255-266
- 113 Böcker U, Dinter D, Litterer C. et al. Comparison of magnetic resonance imaging and video capsule enteroscopy in diagnosing small-bowel pathology: localization-dependent diagnostic yield. Scand J Gastroenterol 2010; 45 (04) 490-500
- 114 Jensen MD, Nathan T, Rafaelsen SR, Kjeldsen J. Diagnostic accuracy of capsule endoscopy for small bowel Crohn's disease is superior to that of MR enterography or CT enterography. Clin Gastroenterol Hepatol 2011; 9 (02) 124-129
- 115 Wiarda BM, Mensink PB, Heine DG. et al. Small bowel Crohn's disease: MR enteroclysis and capsule endoscopy compared to balloon-assisted enteroscopy. Abdom Imaging 2012; 37 (03) 397-403
- 116 Kovanlikaya A, Watson E, Hayward J. et al. Magnetic resonance enterography and wireless capsule endoscopy in the evaluation of patients with inflammatory bowel disease. Clin Imaging 2013; 37 (01) 77-82
- 117 Aloi M, Di Nardo G, Romano G. et al. Magnetic resonance enterography, small-intestine contrast US, and capsule endoscopy to evaluate the small bowel in pediatric Crohn's disease: a prospective, blinded, comparison study. Gastrointest Endosc 2015; 81 (02) 420-427
- 118 González-Suárez B, Rodriguez S, Ricart E. et al. Comparison of capsule endoscopy and magnetic resonance enterography for the assessment of small bowel lesions in Crohn's disease. Inflamm Bowel Dis 2018; 24 (04) 775-780
- 119 Cheifetz AS, Kornbluth AA, Legnani P. et al. The risk of retention of the capsule endoscope in patients with known or suspected Crohn's disease. Am J Gastroenterol 2006; 101 (10) 2218-2222
- 120 Pasha SF, Pennazio M, Rondonotti E. et al. Capsule retention in Crohn's disease: a meta-analysis. Inflamm Bowel Dis 2020; 26 (01) 33-42
- 121 Albuquerque A, Cardoso H, Marques M. et al. Predictive factors of small bowel patency in Crohn's disease patients. Rev Esp Enferm Dig 2016; 108 (02) 65-70
- 122 Rozendorn N, Klang E, Lahat A. et al. Prediction of patency capsule retention in known Crohn's disease patients by using magnetic resonance imaging. Gastrointest Endosc 2016; 83 (01) 182-187
- 123 Nemeth A, Kopylov U, Koulaouzidis A. et al. Use of patency capsule in patients with established Crohn's disease. Endoscopy 2016; 48 (04) 373-379
- 124 Delvaux M, Ben Soussan E, Laurent V, Lerebours E, Gay G. Clinical evaluation of the use of the M2A patency capsule system before a capsule endoscopy procedure, in patients with known or suspected intestinal stenosis. Endoscopy 2005; 37 (09) 801-807
- 125 Signorelli C, Rondonotti E, Villa F. et al. Use of the given patency system for the screening of patients at high risk for capsule retention. Dig Liver Dis 2006; 38 (05) 326-330
- 126 Spada C, Shah SK, Riccioni ME. et al. Video capsule endoscopy in patients with known or suspected small bowel stricture previously tested with the dissolving patency capsule. J Clin Gastroenterol 2007; 41 (06) 576-582
- 127 Atay O, Mahajan L, Kay M, Mohr F, Kaplan B, Wyllie R. Risk of capsule endoscope retention in pediatric patients: a large single-center experience and review of the literature. J Pediatr Gastroenterol Nutr 2009; 49 (02) 196-201
- 128 Cohen SA, Gralnek IM, Ephrath H, Stallworth A, Wakhisi T. The use of a patency capsule in pediatric Crohn's disease: a prospective evaluation. Dig Dis Sci 2011; 56 (03) 860-865
- 129 Singeap AM, Trifan A, Cojocariu C, Sfarti C, Stanciu C. Outcomes after symptomatic capsule retention in suspected small bowel obstruction. Eur J Gastroenterol Hepatol 2011; 23 (10) 886-890
- 130 Fork FT, Karlsson N, Kadhem S, Ohlsson B. Small bowel enteroclysis with magnetic resonance imaging and computed tomography in patients with failed and uncertain passage of a patency capsule. BMC Med Imaging 2012; 12: 3
- 131 Kono T, Hida N, Nogami K. et al. Prospective postsurgical capsule endoscopy in patients with Crohn's disease. World J Gastrointest Endosc 2014; 6 (03) 88-98
- 132 Nakano M, Oka S, Tanaka S. et al. Clinical usefulness of transabdominal ultrasonography prior to patency capsule for suspected small-bowel strictures. Scand J Gastroenterol 2016; 51 (03) 281-287
- 133 Klang E, Kopylov U, Ben-Horin S. et al. Assessment of patency capsule retention using MR diffusion-weighted imaging. Eur Radiol 2017; 27 (12) 4979-4985
- 134 Yoshimura T, Hirooka Y, Nakamura M. et al. Clinical significance of gastrointestinal patency evaluation by using patency capsule in Crohn's disease. Nagoya J Med Sci 2018; 80 (01) 121-128
- 135 Silva M, Cardoso H, Cunha R. et al. Evaluation of small-bowel patency in Crohn's disease: prospective study with a patency capsule and computed tomography. GE Port J Gastroenterol 2019; 26 (06) 396-403
- 136 Otsuka H, Nakamura M, Yamamura T. et al. Feasibility of patency capsule and colon capsule endoscopy in patients with suspected gastrointestinal stenosis: a prospective study. Nagoya J Med Sci 2021; 83 (03) 419-430
- 137 Makipour K, Modiri AN, Ehrlich A. et al. Double balloon enteroscopy: effective and minimally invasive method for removal of retained video capsules. Dig Endosc 2014; 26 (05) 646-649
- 138 Mitsui K, Fujimori S, Tanaka S. et al. Retrieval of retained capsule endoscopy at small bowel stricture by double-balloon endoscopy significantly decreases surgical treatment. J Clin Gastroenterol 2016; 50 (02) 141-146
- 139 Inavolu P, Singh AP, Kanakagiri H, Reddy DN, Ramchandani M. Motorized spiral enteroscope-assisted retrieval of video capsule in a patient with Crohn's disease. VideoGIE 2020; 5 (10) 488-491
- 140 Wang YC, Pan J, Liu YW. et al. Adverse events of video capsule endoscopy over the past two decades: a systematic review and proportion meta-analysis. BMC Gastroenterol 2020; 20 (01) 364
- 141 Han ZM, Qiao WG, Ai XY. et al. Impact of capsule endoscopy on prevention of postoperative recurrence of Crohn's disease. Gastrointest Endosc 2018; 87 (06) 1489-1498
- 142 Bourreille A, Jarry M, D'Halluin PN. et al. Wireless capsule endoscopy versus ileocolonoscopy for the diagnosis of postoperative recurrence of Crohn's disease: a prospective study. Gut 2006; 55 (07) 978-983
- 143 Biancone L, Calabrese E, Petruzziello C. et al. Wireless capsule endoscopy and small intestine contrast ultrasonography in recurrence of Crohn's disease. Inflamm Bowel Dis 2007; 13 (10) 1256-1265
- 144 Pons Beltrán V, Nos P, Bastida G. et al. Evaluation of postsurgical recurrence in Crohn's disease: a new indication for capsule endoscopy?. Gastrointest Endosc 2007; 66 (03) 533-540
- 145 Hausmann J, Schmelz R, Walldorf J, Filmann N, Zeuzem S, Albert JG. Pan-intestinal capsule endoscopy in patients with postoperative Crohn's disease: a pilot study. Scand J Gastroenterol 2017; 52 (08) 840-845
- 146 Kusaka J, Shiga H, Kuroha M. et al. Residual lesions on capsule endoscopy is associated with postoperative clinical recurrence in patients with Crohn's disease. Dig Dis Sci 2018; 63 (03) 768-774
- 147 Shiga H, Abe I, Kusaka J. et al. Capsule endoscopy is useful for postoperative tight control management in patients with Crohn's disease. Dig Dis Sci 2022; 67 (01) 263-272
- 148 Cohen SA, Klevens AI. Use of capsule endoscopy in diagnosis and management of pediatric patients, based on meta-analysis. Clin Gastroenterol Hepatol 2011; 9 (06) 490-496
- 149 Higurashi T, Endo H, Yoneda M. et al. Capsule-endoscopic findings of ulcerative colitis patients. Digestion 2011; 84 (04) 306-314
- 150 Hisabe T, Ninomiya K, Matsui T. et al. Small bowel lesions detected with wireless capsule endoscopy in patients with active ulcerative colitis and with post-proctocolectomy. Dig Endosc 2011; 23 (04) 302-309
- 151 Sung J, Ho KY, Chiu HM, Ching J, Travis S, Peled R. The use of Pillcam Colon in assessing mucosal inflammation in ulcerative colitis: a multicenter study. Endoscopy 2012; 44 (08) 754-758
- 152 Hosoe N, Matsuoka K, Naganuma M. et al. Applicability of second-generation colon capsule endoscope to ulcerative colitis: a clinical feasibility study. J Gastroenterol Hepatol 2013; 28 (07) 1174-1179
- 153 Meister T, Heinzow HS, Domagk D. et al. Colon capsule endoscopy versus standard colonoscopy in assessing disease activity of ulcerative colitis: a prospective trial. Tech Coloproctol 2013; 17 (06) 641-646
- 154 Ye CA, Gao YJ, Ge ZZ. et al. PillCam colon capsule endoscopy versus conventional colonoscopy for the detection of severity and extent of ulcerative colitis. J Dig Dis 2013; 14 (03) 117-124
- 155 Oliva S, Di Nardo G, Hassan C. et al. Second-generation colon capsule endoscopy vs. colonoscopy in pediatric ulcerative colitis: a pilot study. Endoscopy 2014; 46 (06) 485-492
- 156 San Juan-Acosta M, Caunedo-Álvarez A, Argüelles-Arias F. et al. Colon capsule endoscopy is a safe and useful tool to assess disease parameters in patients with ulcerative colitis. Eur J Gastroenterol Hepatol 2014; 26 (08) 894-901
- 157 Shi HY, Chan FKL, Higashimori A. et al. A prospective study on second-generation colon capsule endoscopy to detect mucosal lesions and disease activity in ulcerative colitis (with video). Gastrointest Endosc 2017; 86 (06) 1139-1146.e6
- 158 Okabayashi S, Kobayashi T, Nakano M. et al. A simple 1-day colon capsule endoscopy procedure demonstrated to be a highly acceptable monitoring tool for ulcerative colitis. Inflamm Bowel Dis 2018; 24 (11) 2404-2412
- 159 Matsubayashi M, Kobayashi T, Okabayashi S. et al. Determining the usefulness of Capsule Scoring Of Ulcerative Colitis in predicting relapse of inactive ulcerative colitis. J Gastroenterol Hepatol 2021; 36 (04) 943-950
- 160 Calabrese C, Fabbri A, Gionchetti P. et al. Controlled study using wireless capsule endoscopy for the evaluation of the small intestine in chronic refractory pouchitis. Aliment Pharmacol Ther 2007; 25 (11) 1311-1316
- 161 Maunoury V, Savoye G, Bourreille A. et al. Value of wireless capsule endoscopy in patients with indeterminate colitis (inflammatory bowel disease type unclassified). Inflamm Bowel Dis 2007; 13 (02) 152-155
- 162 Lopes S, Figueiredo P, Portela F. et al. Capsule endoscopy in inflammatory bowel disease type unclassified and indeterminate colitis serologically negative. Inflamm Bowel Dis 2010; 16 (10) 1663-1668
- 163 Ouahed J, Shagrani M, Sant'Anna A. Role of wireless capsule endoscopy in reclassifying inflammatory bowel disease in children. J Pediatr (Rio J) 2013; 89 (02) 204-209
- 164 Monteiro S, Dias de Castro F, Boal Carvalho P. et al. Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified. World J Gastrointest Endosc 2017; 9 (01) 34-40
- 165 Gralnek IM, Defranchis R, Seidman E, Leighton JA, Legnani P, Lewis BS. Development of a capsule endoscopy scoring index for small bowel mucosal inflammatory change. Aliment Pharmacol Ther 2008; 27 (02) 146-154
- 166 Cotter J, Dias de Castro F, Magalhães J, Moreira MJ, Rosa B. Validation of the Lewis score for the evaluation of small-bowel Crohn's disease activity. Endoscopy 2015; 47 (04) 330-335
- 167 Dias de Castro F, Boal Carvalho P, Monteiro S. et al. Lewis Score—prognostic value in patients with isolated small bowel Crohn's disease. J Crohn's Colitis 2015; 9 (12) 1146-1151
- 168 Monteiro S, Boal Carvalho P, Dias de Castro F. et al. Capsule endoscopy: diagnostic accuracy of Lewis score in patients with suspected Crohn's disease. Inflamm Bowel Dis 2015; 21 (10) 2241-2246
- 169 He C, Zhang J, Chen Z. et al. Relationships of capsule endoscopy Lewis score with clinical disease activity indices, C-reactive protein, and small bowel transit time in pediatric and adult patients with small bowel Crohn's disease. Medicine (Baltimore) 2017; 96 (33) e7780
- 170 Klang E, Amitai MM, Lahat A. et al; Israeli IBD research Nucleus [IIRN). Capsule endoscopy validation of the magnetic enterography global score in patients with established Crohn's disease. J Crohn's Colitis 2018; 12 (03) 313-320
- 171 Nishikawa T, Nakamura M, Yamamura T. et al. Lewis score on capsule endoscopy as a predictor of the risk for Crohn's disease-related emergency hospitalization and clinical relapse in patients with small bowel Crohn's disease. Gastroenterol Res Pract 2019; 2019: 4274257
- 172 Nishikawa T, Nakamura M, Yamamura T. et al. Lewis score on capsule endoscopy can predict the prognosis in patients with small bowel lesions of Crohn's disease. J Gastroenterol Hepatol 2021; 36 (07) 1851-1858
- 173 Gal E, Geller A, Fraser G, Levi Z, Niv Y. Assessment and validation of the new capsule endoscopy Crohn's disease activity index (CECDAI). Dig Dis Sci 2008; 53 (07) 1933-1937
- 174 Niv Y, Ilani S, Levi Z. et al. Validation of the Capsule Endoscopy Crohn's Disease Activity Index (CECDAI or Niv score): a multicenter prospective study. Endoscopy 2012; 44 (01) 21-26
- 175 Ponte A, Pinho R, Rodrigues A. et al. Evaluation and comparison of capsule endoscopy scores for assessment of inflammatory activity of small-bowel in Crohn's disease. Gastroenterol Hepatol 2018; 41 (04) 245-250
- 176 Koulaouzidis A, Douglas S, Plevris JN. Lewis score correlates more closely with fecal calprotectin than Capsule Endoscopy Crohn's Disease Activity Index. Dig Dis Sci 2012; 57 (04) 987-993
- 177 Miyazu T, Ishida N, Takano R. et al. Usefulness of the capsule endoscopy Crohn's disease activity index in assessing the necessity of early additional treatment in patients with Crohn's disease in clinical remission. Medicine (Baltimore) 2021; 100 (29) e26550
- 178 Niv Y, Gal E, Gabovitz V, Hershkovitz M, Lichtenstein L, Avni I. Capsule Endoscopy Crohn's Disease Activity Index (CECDAIic or Niv Score) for the Small Bowel and Colon. J Clin Gastroenterol 2018; 52 (01) 45-49
- 179 Arieira C, Magalhães R, Dias de Castro F. et al. CECDAIic - a new useful tool in pan-intestinal evaluation of Crohn's disease patients in the era of mucosal healing. Scand J Gastroenterol 2019; 54 (11) 1326-1330
- 180 Eliakim R, Yablecovitch D, Lahat A. et al. A novel PillCam Crohn's capsule score (Eliakim score) for quantification of mucosal inflammation in Crohn's disease. United European Gastroenterol J 2020; 8 (05) 544-551
- 181 Hosoe N, Nakano M, Takeuchi K. et al. Establishment of a novel scoring system for colon capsule endoscopy to assess the severity of Ulcerative Colitis-Capsule Scoring Of Ulcerative Colitis. Inflamm Bowel Dis 2018; 24 (12) 2641-2647
- 182 Macedo Silva V, Freitas M, Boal Carvalho P. et al. Apex Score: predicting flares in small-bowel Crohn's disease after mucosal healing. Dig Dis Sci 2022; 67 (04) 1278-1286
- 183 Jensen MD, Nathan T, Kjeldsen J. Inter-observer agreement for detection of small bowel Crohn's disease with capsule endoscopy. Scand J Gastroenterol 2010; 45 (7-8): 878-884
- 184 Kumar R, Zhao Q, Seshamani S, Mullin G, Hager G, Dassopoulos T. Assessment of Crohn's disease lesions in wireless capsule endoscopy images. IEEE Trans Biomed Eng 2012; 59 (02) 355-362
- 185 Charisis VS, Hadjileontiadis LJ. Potential of hybrid adaptive filtering in inflammatory lesion detection from capsule endoscopy images. World J Gastroenterol 2016; 22 (39) 8641-8657
- 186 Klang E, Barash Y, Margalit RY. et al. Deep learning algorithms for automated detection of Crohn's disease ulcers by video capsule endoscopy. Gastrointest Endosc 2020; 91 (03) 606-613.e2
- 187 Barash Y, Azaria L, Soffer S. et al. Ulcer severity grading in video capsule images of patients with Crohn's disease: an ordinal neural network solution. Gastrointest Endosc 2021; 93 (01) 187-192
- 188 Klang E, Grinman A, Soffer S. et al. Automated detection of Crohn's disease intestinal strictures on capsule endoscopy images using deep neural networks. J Crohn's Colitis 2021; 15 (05) 749-756
- 189 Klang E, Kopylov U, Mortensen B. et al. A convolutional neural network deep learning model trained on CD ulcers images accurately identifies NSAID ulcers. Front Med (Lausanne) 2021; 8: 656493
- 190 de Maissin A, Vallée R, Flamant M. et al. Multi-expert annotation of Crohn's disease images of the small bowel for automatic detection using a convolutional recurrent attention neural network. Endosc Int Open 2021; 9 (07) E1136-E1144
- 191 Ferreira JPS, de Mascarenhas Saraiva MJDQEC, Afonso JPL. et al. Identification of ulcers and erosions by the novel Pillcam™ Crohn's capsule using a convolutional neural network: a multicentre pilot study. J Crohn's Colitis 2022; 16 (01) 169-172
- 192 Higuchi N, Hiraga H, Sasaki Y. et al. Automated evaluation of colon capsule endoscopic severity of ulcerative colitis using ResNet50. PLoS One 2022; 17 (06) e0269728
- 193 Koulaouzidis A, Smirnidis A, Douglas S, Plevris JN. QuickView in small-bowel capsule endoscopy is useful in certain clinical settings, but QuickView with Blue Mode is of no additional benefit. Eur J Gastroenterol Hepatol 2012; 24 (09) 1099-1104
- 194 Halling ML, Nathan T, Kjeldsen J, Jensen MD. High sensitivity of quick view capsule endoscopy for detection of small bowel Crohn's disease. J Gastroenterol Hepatol 2014; 29 (05) 992-996
- 195 Tontini GE, Cavallaro F, Neumann H, Pastorelli L, Neurath MF, Spina L. et al. Extensive small-bowel Crohn's disease detected by the newly introduced 360° panoramic viewing capsule endoscopy system. Endoscopy 2014; 46 (Suppl 1 UCTN): E353-E354
- 196 Freitas M, Arieira C, Carvalho PB, Rosa B, Moreira MJ, Cotter J. Simplify to improve in capsule endoscopy—TOP 100 is a swift and reliable evaluation tool for the small bowel inflammatory activity in Crohn's disease. Scand J Gastroenterol 2020; 55 (04) 408-413
- 197 Nam SJ, Lim YJ, Nam JH. et al. 3D reconstruction of small bowel lesions using stereo camera-based capsule endoscopy. Sci Rep 2020; 10 (01) 6025
- 198 Tontini GE, Rizzello F, Cavallaro F. et al. Usefulness of panoramic 344°-viewing in Crohn's disease capsule endoscopy: a proof of concept pilot study with the novel PillCam™ Crohn's system. BMC Gastroenterol 2020; 20 (01) 97
- 199 Yung DE, Robertson AR, Davie M. et al. Double-headed small-bowel capsule endoscopy: real-world experience from a multi-centre British study. Dig Liver Dis 2021; 53 (04) 461-466
- 200 Oliva S, Cucchiara S, Spada C. et al. Small bowel cleansing for capsule endoscopy in paediatric patients: a prospective randomized single-blind study. Dig Liver Dis 2014; 46 (01) 51-55
- 201 Semenov S, Ismail MS, O'Hara F. et al. Addition of castor oil as a booster in colon capsule regimens significantly improves completion rates and polyp detection. World J Gastrointest Pharmacol Ther 2021; 12 (06) 103-112