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CC BY-NC-ND 4.0 · International Journal of Epilepsy 2022; 08(01): 035-042
DOI: 10.1055/s-0043-1764397
Case Report

Extreme Sleep Spindles in Children with Autism Spectrum Disorder and Related Disorders—A Case Series

Sowmyashree Mayur Kaku 
1   Centre for Advanced Research and Excellence in Autism and Developmental Disorders, St. John's Medical College Hospital, Bengaluru, Karnataka, India
,
Manjula William James
1   Centre for Advanced Research and Excellence in Autism and Developmental Disorders, St. John's Medical College Hospital, Bengaluru, Karnataka, India
,
Gosala R. K. Sarma 
1   Centre for Advanced Research and Excellence in Autism and Developmental Disorders, St. John's Medical College Hospital, Bengaluru, Karnataka, India
2   Department of Neurology, St. John's Medical College Hospital, Bengaluru, Karnataka, India
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Abstract

Extreme sleep spindles have fast activity and high amplitude, unlike normal sleep spindles. We report a case series of six children with autism and related disorders who had extreme spindles as noted on the sleep electroencephalogram recording at our center. We examine the types of extreme spindles, describe the clinical profiles of the 6 children, and discuss similar clinical and neurophysiological conditions.

Keywords

autism - EEG - extreme spindles - neurodevelopmental disorders - sleep spindles

Note

This series is part of a larger ongoing study with ethics approval (IEC.No.379/2021).




Publication History

Article published online:
10 April 2023

© 2023. Indian Epilepsy Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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