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Semin Musculoskelet Radiol 2023; 27(01): 030-044
DOI: 10.1055/s-0043-1761495
Review Article

Normal Bone Marrow and Non-neoplastic Systemic Hematopoietic Disorders in the Adult

Philippa Anne Tyler
1   Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, United Kingdom
,
Ramanan Rajakulasingam
1   Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, United Kingdom
,
Asif Saifuddin
1   Royal National Orthopaedic Hospital, Brockley Hill, Stanmore, United Kingdom
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Abstract

This article provides an overview of the imaging appearances of normal adult bone marrow with an emphasis on magnetic resonance imaging. We also review the cellular processes and imaging features of normal developmental yellow-to-red marrow conversion and compensatory physiologic or pathologic red marrow reconversion. Key imaging features that differentiate between normal adult marrow, normal variants, non-neoplastic hematopoietic disorders, and malignant marrow disease are discussed, as well as posttreatment changes.

Keywords

marrow reconversion - magnetic resonance imaging - hematopoietic - red and yellow bone marrow


Publication History

Article published online:
03 March 2023

© 2023. Thieme. All rights reserved.

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