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Int J Angiol 2023; 32(03): 158-164
DOI: 10.1055/s-0043-1761290
Original Article

Acute Limb Ischemia after Cardiovascular Surgery: A Deadly Duo Combination with High Mortality

Suci Indriani 
1   Department of Cardiology and Vascular Medicine, Universitas Indonesia/Harapan Kita National Cardiovascular Center, Jakarta, Indonesia
,
Raditya Dewangga 
2   Department of Emergency Medicine, Gunung Jati General Hospital, Cirebon, Indonesia
,
Suko Adiarto 
1   Department of Cardiology and Vascular Medicine, Universitas Indonesia/Harapan Kita National Cardiovascular Center, Jakarta, Indonesia
,
Taofan Siddiq 
1   Department of Cardiology and Vascular Medicine, Universitas Indonesia/Harapan Kita National Cardiovascular Center, Jakarta, Indonesia
,
Iwan Dakota
1   Department of Cardiology and Vascular Medicine, Universitas Indonesia/Harapan Kita National Cardiovascular Center, Jakarta, Indonesia
,
Hananto Andriantoro
1   Department of Cardiology and Vascular Medicine, Universitas Indonesia/Harapan Kita National Cardiovascular Center, Jakarta, Indonesia
,
Marc Vuylsteke
3   Department of Vascular Surgery, Sint-Andriesziekenhuis, Tielt, Belgium
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Abstract

Acute limb ischemia (ALI) is a predictor of high morbidity and mortality. Previous studies showed that ALI developed after cardiac surgery may increase mortality.

This study aimed to elucidate the clinical course and identify risk factors contributing to mortality in patients with ALI after cardiovascular surgery.

This is a single-center retrospective cohort study. We analyzed data from 52 patients with ALI after cardiovascular surgery between 2016 and 2020. We evaluated the risk factors for 1-year mortality using Cox proportional hazards regression analysis.

Most of the patients with ALI were male and the median age was 56 years (23–72 years). Most of the patients with ALI had coronary artery diseases. The 1-year mortality rate was 55.8% (n = 29 patients). Multivariable analysis revealed that cardiopulmonary bypass (CPB) time ≥ 100 minutes (hazard ratio [HR]: 3.067, 95% confidence interval [CI]: 1.158–8.120) and postoperative acute kidney injury (HR: 2.927, 95% CI: 1.358–6.305) were significantly increasing the risk of mortality in patients with ALI after an operation. ALI after cardiovascular surgery was associated with high 1-year mortality in our study and long CPB time and postoperative acute kidney injury contributed to the mortality.

Keywords

acute limb ischemia - cardiovascular surgery - mortality


Publication History

Article published online:
13 February 2023

© 2023. International College of Angiology. This article is published by Thieme.

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