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DOI: 10.1055/s-0043-122301
Das Mikrobiom – die unplanbare Größe zukünftiger Therapien
Article in several languages: deutsch | EnglishPublication History
Publication Date:
22 March 2018 (online)
![](https://www.thieme-connect.de/media/lro/2018S01/lookinside/thumbnails/5045327_10-1055-s-0043-122301_de-1.jpg)
Zusammenfassung
Unter Mikrobiom versteht man die Gesamtheit der bakteriellen, parasitären, viralen oder anderen zellulären Mikroorganismen, die den menschlichen Körper oder ein anderes Lebewesen besiedeln. Das Mikrobiom zeigt in den anatomischen Bereichen der Hals-Nasen-Ohrenheilkunde eine deutliche regionale Varianz. Für die Bereiche von Ohr, Nase, Rachen, Larynx und Haut sind jeweils verschiedene Interaktionen des Mikrobiomes mit allgemeinen Faktoren wie Alter, Diät und Lebensstilfaktoren (z. B. Rauchen) in den letzten Jahren bekannt geworden. Zudem liegen eine Reihe von Erkenntnissen vor, dass das Mikrobiom an der Pathogenese verschiedener Erkrankungen auch im HNO-Bereich beteiligt ist. Der vorgestellte Übersichtsartikel fasst die wesentlichen Erkenntnisse dieses sich aktuell äußerst rasch entwickelnden Forschungsgebietes überblickartig zusammen.
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