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DOI: 10.1055/s-0043-109425
Transgastric retrograde endoscopic ultrasound sampling of a mediastinal mass in a patient with radiation-induced trismus
Publikationsverlauf
Publikationsdatum:
30. Mai 2017 (online)
![](https://www.thieme-connect.de/media/endoscopy/201707/lookinside/thumbnails/0133_10-1055-s-0043-109425-1.jpg)
Endoscopic ultrasound (EUS) guidance is a safe and effective technique for sampling mediastinal lesions [1] [2] [3]. We report a case where an EUS was done in retrograde fashion through a gastrostomy because of the patient’s limited degree of mouth opening due to trismus.
We present the case of a 42-year-old man with oropharyngeal squamous cell carcinoma (SCC) who had had a suboptimal response to chemoradiation and was therefore undergoing evaluation for surgery. A positron emission tomography (PET) scan showed a hypermetabolic mediastinal lesion. If this mediastinal lesion was a metastatic focus, the patient would not benefit from surgery and therefore sampling was required. An initial EUS-guided fine needle aspiration (FNA) failed as the echoendoscope could not be passed through the patient’s mouth because of his radiation-induced trismus. After multidisciplinary discussion, we proceeded with retrograde EUS-FNA of the mediastinal mass performed through the patient’s pre-existing gastrostomy ([Video 1]).
Video 1 Video demonstrating retrograde endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) through an existing gastrostomy for sampling of a mediastinal mass in a patient with radiation-induced trismus.
Qualität:
The procedure was performed with the patient under general anesthesia. The existing gastrostomy tube was removed and, after serial dilation of the gastrostomy tract, was replaced with a 15-mm laparoscopic trocar. A standard gastroscope was passed through the trocar and two hemoclips were placed in the gastric cardia to aid identification of the gastroesophageal junction (GEJ) during echoendoscope passage. A radial echoendoscope (GF-UE160-AL5; Olympus, Tokyo, Japan) was inserted through the trocar and advanced in retrograde fashion through the GEJ until the mediastinal mass was identified ([Fig. 1]). The radial echoendoscope was then exchanged for a linear echoendoscope (UC140P-AL5; Olympus) to perform the EUS-FNA ([Fig. 2]). Two passes with a 22G needle were diagnostic for carcinoma by on-site cytology. The linear echoendoscope and trocar were removed and a balloon-type gastrostomy tube was placed.
![](https://www.thieme-connect.de/media/endoscopy/201707/thumbnails/10-1055-s-0043-109425-i0133cl1.jpg)
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![](https://www.thieme-connect.de/media/endoscopy/201707/thumbnails/10-1055-s-0043-109425-i0133cl2.gif)
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Final pathology confirmed metastasis of the SCC. The patient was discharged on the same day without complications and was later started on palliative immunotherapy.
Retrograde EUS-FNA through a gastrostomy for mediastinal mass sampling seems to be safe and feasible, and offers a novel solution for patients in whom the antegrade route is not available.
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References
- 1 Fritscher-Ravens A, Sriram PVJ, Bobrowski C. et al. Mediastinal lymphadenopathy in patients with or without previous malignancy: EUS-FNA-based differential cytodiagnosis in 153 patients. Am J Gastroenterol 2000; 95: 2278-2284
- 2 Powers CN, Silverman JF, Geisinger KR. et al. Fine-needle aspiration biopsy of the mediastinum. A multi-institutional analysis. Am J Clin Pathol 1996; 105: 168-173
- 3 Pedersen BH, Vilmann P, Folke K. et al. Endoscopic ultrasonography and real-time guided fine-needle aspiration biopsy of solid lesions of the mediastinum suspected of malignancy. Chest 1996; 110: 539-544