Der Einfluss intraokularer Druckschwankungen auf die Glaukomerkrankung

Zusammenfassung

Als derzeit einzig zu behandelnder Risikofaktor spielt der Augeninnendruck für das Fortschreiten der Glaukomerkrankung immer noch eine große Rolle. Zwei große klinische Studien (Schweden und USA) haben den Einfluss des Augeninnendrucks und seiner Schwankungen – definiert als Standardabweichung des Mittelwerts – auf die Glaukomprogression untersucht. Neben diesen großen randomisierten klinischen Studien gibt es eine Reihe von kleineren Untersuchungen zu diesem Zusammenhang. In dieser Übersichtsarbeit sind die wichtigsten Studien zusammengefasst.

Abstract

Intraocular pressure fluctuation has been discussed as a risk factor for glaucoma development and glaucoma progression. Two clinical trials (Sweden and USA) have evaluated the relationship between IOP and glaucoma progression. Both studies will be discussed in this review. Additionally, some smaller studies exist that are mentioned and discussed as well. This review summarizes the most important studies.

Schlüsselwörter

Glaukom - Risikofaktoren - Progression Glaukom - Glaukomdiagnostik - Augeninnendruck

Key words

glaucoma - risk factors - glaucoma progression - IOP - glaucoma diagnostics

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