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CC BY-NC-ND 4.0 · Revista Chilena de Ortopedia y Traumatología 2022; 63(03): e195-e204
DOI: 10.1055/s-0042-1759741
Artículo de Revisión | Review Article

Rheumatoid Arthritis of the Cervical Spine – Key Aspects for the Orthopedic Surgeon

Artikel in mehreren Sprachen: español | English
Pablo Enrique Krainz 
1   Departamento Ortopedia y Traumatología, Clínica Indisa, Providencia, Santiago, Chile
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Abstract

Rheumatoid arthritis is a chronic inflammatory autoimmune disease that frequently affects the cervical spine. The clinical diagnosis can be difficult; therefore, a systematic radiographic evaluation of all patients is recommended. The timely treatment of these lesions is important to preserve the self-reliance, the neurological function, and even the lives of the patients. The present article is an update of all the aspects pertaining to cervical spine rheumatoid arthritis that are relevant to the orthopedic surgeon.

Keywords

atlantoaxial instability - cervical spine - morbidity - rheumatoid arthritis - surgery


Publikationsverlauf

Eingereicht: 10. Dezember 2021

Angenommen: 28. September 2022

Artikel online veröffentlicht:
28. Dezember 2022

© 2022. Sociedad Chilena de Ortopedia y Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • Referencias

  • 1 Lipsky P. Harrison's Principles of Internal Medicine. 15th ed.. Mc Graw Hill; 1929
    Google Scholar
  • 2 Aletaha D, Neogi T, Silman AJ. et al. 2010 Rheumatoid arthritis classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum 2010; 62 (09) 2569-2581
    CrossrefPubMedGoogle Scholar
  • 3 Shlobin NA, Dahdaleh NS. Cervical spine manifestations of rheumatoid arthritis: a review. Neurosurg Rev 2021; 44 (04) 1957-1965
    CrossrefPubMedGoogle Scholar
  • 4 Oda T, Fujiwara K, Yonenobu K, Azuma B, Ochi T. Natural course of cervical spine lesions in rheumatoid arthritis. Spine 1995; 20 (10) 1128-1135
    CrossrefPubMedGoogle Scholar
  • 5 Mathews JA. Atlanto-axial subluxation in rheumatoid arthritis. Ann Rheum Dis 1969; 28 (03) 260-266
    CrossrefPubMedGoogle Scholar
  • 6 Collins DN, Barnes CL, FitzRandolph RL. Cervical spine instability in rheumatoid patients having total hip or knee arthroplasty. Clin Orthop Relat Res 1991; (272) 127-135
    PubMedGoogle Scholar
  • 7 Sharp J, Purser DW, Lawrence JS. Rheumatoid arthritis of the cervical spine in the adult. Ann Rheum Dis 1958; 17 (03) 303-313
    CrossrefPubMedGoogle Scholar
  • 8 Zhang T, Pope J. Cervical spine involvement in rheumatoid arthritis over time: results from a meta-analysis. Arthritis Res Ther 2015; 17: 148 DOI: 10.1186/s13075-015-0643-0.
    CrossrefPubMedGoogle Scholar
  • 9 Dreyer SJ, Boden SD. Natural history of rheumatoid arthritis of the cervical spine. Clin Orthop Relat Res 1999; (366) 98-106
    CrossrefPubMedGoogle Scholar
  • 10 Ranawat CS, O'Leary P, Pellicci P, Tsairis P, Marchisello P, Dorr L. Cervical spine fusion in rheumatoid arthritis. J Bone Joint Surg Am 1979; 61 (07) 1003-1010
    CrossrefPubMedGoogle Scholar
  • 11 Gillick JL, Wainwright J, Das K. Rheumatoid Arthritis and the Cervical Spine: A Review on the Role of Surgery. Int J Rheumatol 2015; 2015: 252456
    CrossrefPubMedGoogle Scholar
  • 12 Weissman BN, Aliabadi P, Weinfeld MS, Thomas WH, Sosman JL. Prognostic features of atlantoaxial subluxation in rheumatoid arthritis patients. Radiology 1982; 144 (04) 745-751
    CrossrefPubMedGoogle Scholar
  • 13 Rasker JJ, Cosh JA. Radiological study of cervical spine and hand in patients with rheumatoid arthritis of 15 years' duration: an assessment of the effects of corticosteroid treatment. Ann Rheum Dis 1978; 37 (06) 529-535
    CrossrefPubMedGoogle Scholar
  • 14 Winfield J, Young A, Williams P, Corbett M. Prospective study of the radiological changes in hands, feet, and cervical spine in adult rheumatoid disease. Ann Rheum Dis 1983; 42 (06) 613-618
    CrossrefPubMedGoogle Scholar
  • 15 Fujiwara K, Fujimoto M, Owaki H. et al. Cervical lesions related to the systemic progression in rheumatoid arthritis. Spine 1998; 23 (19) 2052-2056
    CrossrefPubMedGoogle Scholar
  • 16 Neva MH, Häkkinen A, Mäkinen H, Hannonen P, Kauppi M, Sokka T. High prevalence of asymptomatic cervical spine subluxation in patients with rheumatoid arthritis waiting for orthopaedic surgery. Ann Rheum Dis 2006; 65 (07) 884-888
    CrossrefPubMedGoogle Scholar
  • 17 Pellicci PM, Ranawat CS, Tsairis P, Bryan WJ. A prospective study of the progression of rheumatoid arthritis of the cervical spine. J Bone Joint Surg Am 1981; 63 (03) 342-350
    CrossrefPubMedGoogle Scholar
  • 18 Dedmon LE. The genetics of rheumatoid arthritis. Rheumatology (Oxford) 2020; 59 (10) 2661-2670
    CrossrefPubMedGoogle Scholar
  • 19 Ruiz-Esquide V, Sanmartí R. Tobacco and other environmental risk factors in rheumatoid arthritis. Reumatol Clin 2012; 8 (06) 342-350
    PubMedGoogle Scholar
  • 20 Rana NA, Hancock DO, Taylor AR, Hill AG. Upward translocation of the dens in rheumatoid arthritis. J Bone Joint Surg Br 1973; 55 (03) 471-477
    CrossrefPubMedGoogle Scholar
  • 21 Sunahara N, Matsunaga S, Mori T, Ijiri K, Sakou T. Clinical course of conservatively managed rheumatoid arthritis patients with myelopathy. Spine 1997; 22 (22) 2603-2607 , discussion 2608
    CrossrefPubMedGoogle Scholar
  • 22 Riise T, Jacobsen BK, Gran JT. High mortality in patients with rheumatoid arthritis and atlantoaxial subluxation. J Rheumatol 2001; 28 (11) 2425-2429
    PubMedGoogle Scholar
  • 23 Mikulowski P, Wollheim FA, Rotmil P, Olsen I. Sudden death in rheumatoid arthritis with atlanto-axial dislocation. Acta Med Scand 1975; 198 (06) 445-451
    CrossrefPubMedGoogle Scholar
  • 24 Meijers KA, Cats A, Kremer HP, Luyendijk W, Onvlee GJ, Thomeer RT. Cervical myelopathy in rheumatoid arthritis. Clin Exp Rheumatol 1984; 2 (03) 239-245
    PubMedGoogle Scholar
  • 25 Zoma A, Sturrock RD, Fisher WD, Freeman PA, Hamblen DL. Surgical stabilisation of the rheumatoid cervical spine. A review of indications and results. J Bone Joint Surg Br 1987; 69 (01) 8-12
    CrossrefPubMedGoogle Scholar
  • 26 Neva MH, Kauppi MJ, Kautiainen H. et al; FIN-RACo Trail Group. Combination drug therapy retards the development of rheumatoid atlantoaxial subluxations. Arthritis Rheum 2000; 43 (11) 2397-2401
    CrossrefPubMedGoogle Scholar
  • 27 Kaito T, Hosono N, Ohshima S. et al. Effect of biological agents on cervical spine lesions in rheumatoid arthritis. Spine 2012; 37 (20) 1742-1746
    CrossrefPubMedGoogle Scholar
  • 28 Harrington R, Al Nokhatha SA, Conway R. JAK Inhibitors in Rheumatoid Arthritis: An Evidence-Based Review on the Emerging Clinical Data. J Inflamm Res 2020; 13: 519-531
    CrossrefPubMedGoogle Scholar
  • 29 Angelini J, Talotta R, Roncato R. et al. JAK-Inhibitors for the Treatment of Rheumatoid Arthritis: A Focus on the Present and an Outlook on the Future. Biomolecules 2020; 10 (07) E1002 DOI: 10.3390/biom10071002.
    CrossrefPubMedGoogle Scholar
  • 30 Riew KD, Hilibrand AS, Palumbo MA, Sethi N, Bohlman HH. Diagnosing basilar invagination in the rheumatoid patient. The reliability of radiographic criteria. J Bone Joint Surg Am 2001; 83 (02) 194-200
    CrossrefPubMedGoogle Scholar
  • 31 Boden SD, Dodge LD, Bohlman HH, Rechtine GR. Rheumatoid arthritis of the cervical spine. A long-term analysis with predictors of paralysis and recovery. J Bone Joint Surg Am 1993; 75 (09) 1282-1297
    CrossrefPubMedGoogle Scholar
  • 32 Joaquim AF, Ghizoni E, Tedeschi H, Appenzeller S, Riew KD. Radiological evaluation of cervical spine involvement in rheumatoid arthritis. Neurosurg Focus 2015; 38 (04) E4
    CrossrefPubMedGoogle Scholar
  • 33 Ellatif M, Sharif B, Baxter D, Saifuddin A. Update on imaging of the cervical spine in rheumatoid arthritis. Skeletal Radiol 2022; 51 (08) 1535-1551 DOI: 10.1007/s00256-022-04012-w.
    CrossrefPubMedGoogle Scholar
  • 34 Reijnierse M, Breedveld FC, Kroon HM, Hansen B, Pope TL, Bloem JL. Are magnetic resonance flexion views useful in evaluating the cervical spine of patients with rheumatoid arthritis?. Skeletal Radiol 2000; 29 (02) 85-89
    CrossrefPubMedGoogle Scholar
  • 35 Dvorak J, Grob D, Baumgartner H, Gschwend N, Grauer W, Larsson S. Functional evaluation of the spinal cord by magnetic resonance imaging in patients with rheumatoid arthritis and instability of upper cervical spine. Spine 1989; 14 (10) 1057-1064
    CrossrefPubMedGoogle Scholar
  • 36 Kawaida H, Sakou T, Morizono Y, Yoshikuni N. Magnetic resonance imaging of upper cervical disorders in rheumatoid arthritis. Spine 1989; 14 (11) 1144-1148
    CrossrefPubMedGoogle Scholar
  • 37 Bundschuh C, Modic MT, Kearney F, Morris R, Deal C. Rheumatoid arthritis of the cervical spine: surface-coil MR imaging. AJR Am J Roentgenol 1988; 151 (01) 181-187
    CrossrefPubMedGoogle Scholar
  • 38 Beaulieu LL, Vial S, Delgado J. et al. Artritis Reumatoídea en Columna Cervical: Algoritmos de Tratamiento. Coluna/Columna 2005; 4 (01) 42-49
    PubMedGoogle Scholar
  • 39 Mallory GW, Halasz SR, Clarke MJ. Advances in the treatment of cervical rheumatoid: Less surgery and less morbidity. World J Orthop 2014; 5 (03) 292-303
    CrossrefPubMedGoogle Scholar
  • 40 Coyne TJ, Fehlings MG, Wallace MC, Bernstein M, Tator CH. C1-C2 posterior cervical fusion: long-term evaluation of results and efficacy. Neurosurgery 1995; 37 (04) 688-692 , discussion 692–693
    CrossrefPubMedGoogle Scholar
  • 41 Chan DP, Ngian KS, Cohen L. Posterior upper cervical fusion in rheumatoid arthritis. Spine 1992; 17 (03) 268-272
    CrossrefPubMedGoogle Scholar
  • 42 Goel A, Laheri V. Plate and screw fixation for atlanto-axial subluxation. Acta Neurochir (Wien) 1994; 129 (1-2): 47-53
    CrossrefPubMedGoogle Scholar
  • 43 Goel A, Desai KI, Muzumdar DP. Atlantoaxial fixation using plate and screw method: a report of 160 treated patients. Neurosurgery 2002; 51 (06) 1351-1356 , discussion 1356–1357
    CrossrefPubMedGoogle Scholar
  • 44 Magerl F, Seemann P-S. Stable Posterior Fusion of the Atlas and Axis by Transarticular Screw Fixation BT - Cervical Spine I: Strasbourg. In: Kehr P, Weidner A. eds. Vienna: Springer Vienna; 1985: 322-327
    Google Scholar
  • 45 Sawin PD, Traynelis VC, Menezes AH. A comparative analysis of fusion rates and donor-site morbidity for autogeneic rib and iliac crest bone grafts in posterior cervical fusions. J Neurosurg 1998; 88 (02) 255-265
    CrossrefPubMedGoogle Scholar
  • 46 Harms J, Melcher RP. Posterior C1-C2 fusion with polyaxial screw and rod fixation. Spine 2001; 26 (22) 2467-2471
    CrossrefPubMedGoogle Scholar
  • 47 Elliott RE, Tanweer O, Boah A. et al. Outcome comparison of atlantoaxial fusion with transarticular screws and screw-rod constructs: meta-analysis and review of literature. J Spinal Disord Tech 2014; 27 (01) 11-28
    CrossrefPubMedGoogle Scholar
  • 48 Meyer B, Kuhlen D. Atlantoaxial fusion: transarticular screws versus screw-rod constructs. World Neurosurg 2013; 80 (05) 516-517
    CrossrefPubMedGoogle Scholar
  • 49 Elliott RE, Tanweer O, Boah A. et al. Atlantoaxial fusion with transarticular screws: meta-analysis and review of the literature. World Neurosurg 2013; 80 (05) 627-641
    CrossrefPubMedGoogle Scholar
  • 50 Elliott RE, Tanweer O, Boah A. et al. Atlantoaxial fusion with screw-rod constructs: meta-analysis and review of literature. World Neurosurg 2014; 81 (02) 411-421
    CrossrefPubMedGoogle Scholar
  • 51 Arslan D, Ozer MA, Govsa F, Kıtıs O. The Ponticulus Posticus as Risk Factor for Screw Insertion into the First Cervical Lateral Mass. World Neurosurg 2018; 113: e579-e585
    CrossrefPubMedGoogle Scholar
  • 52 Alosh H, Parker SL, McGirt MJ. et al. Preoperative radiographic factors and surgeon experience are associated with cortical breach of C2 pedicle screws. J Spinal Disord Tech 2010; 23 (01) 9-14
    CrossrefPubMedGoogle Scholar
  • 53 Elliott RE, Tanweer O, Boah A, Smith ML, Frempong-Boadu A. Comparison of safety and stability of C-2 pars and pedicle screws for atlantoaxial fusion: meta-analysis and review of the literature. J Neurosurg Spine 2012; 17 (06) 577-593
    CrossrefPubMedGoogle Scholar
  • 54 Wright NM. Posterior C2 fixation using bilateral, crossing C2 laminar screws: case series and technical note. J Spinal Disord Tech 2004; 17 (02) 158-162
    Google Scholar
  • 55 Cassinelli EH, Lee M, Skalak A, Ahn NU, Wright NM. Anatomic considerations for the placement of C2 laminar screws. Spine 2006; 31 (24) 2767-2771
    CrossrefPubMedGoogle Scholar
  • 56 Cristante AF, Torelli AG, Kohlmann RB. et al. Feasibility of intralaminar, lateral mass, or pedicle axis vertebra screws in children under 10 years of age: a tomographic study. Neurosurgery 2012; 70 (04) 835-838 , discussion 838–839
    CrossrefPubMedGoogle Scholar
  • 57 Sakuraba K, Omori Y, Kai K. et al. Risk factor analysis of perioperative complications in patients with rheumatoid arthritis undergoing primary cervical spine surgery. Arthritis Res Ther 2022; 24 (01) 79 DOI: 10.1186/s13075-022-02767-0.
    CrossrefPubMedGoogle Scholar
  • 58 Bernstein DN, Kurucan E, Menga EN, Molinari RW, Rubery PT, Mesfin A. Comparison of adult spinal deformity patients with and without rheumatoid arthritis undergoing primary non-cervical spinal fusion surgery: a nationwide analysis of 52,818 patients. Spine J 2018; 18 (10) 1861-1866
    CrossrefPubMedGoogle Scholar
  • 59 Schmitt-Sody M, Kirchhoff C, Buhmann S. et al. Timing of cervical spine stabilisation and outcome in patients with rheumatoid arthritis. Int Orthop 2008; 32 (04) 511-516
    CrossrefPubMedGoogle Scholar
  • 60 Wolfs JFC, Kloppenburg M, Fehlings MG, van Tulder MW, Boers M, Peul WC. Neurologic outcome of surgical and conservative treatment of rheumatoid cervical spine subluxation: a systematic review. Arthritis Rheum 2009; 61 (12) 1743-1752
    CrossrefPubMedGoogle Scholar
  • 61 Clarke MJ, Cohen-Gadol AA, Ebersold MJ, Cabanela ME. Long-term incidence of subaxial cervical spine instability following cervical arthrodesis surgery in patients with rheumatoid arthritis. Surg Neurol 2006; 66 (02) 136-140 , discussion 140
    CrossrefPubMedGoogle Scholar