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CC BY 4.0 · Journal of Digestive Endoscopy 2023; 14(01): 056-059
DOI: 10.1055/s-0042-1759511
Case Report

Extramedullary Plasmacytoma: A Rare Entity

Pastor Joaquín Ortiz Mendieta
1   Endoscopy Unit, Cancer Institute of São Paulo – ICESP, São Paulo, Brazil
,
Luciano Henrique Lenz Tolentino 
1   Endoscopy Unit, Cancer Institute of São Paulo – ICESP, São Paulo, Brazil
,
Deborah Marques Centeno
1   Endoscopy Unit, Cancer Institute of São Paulo – ICESP, São Paulo, Brazil
,
John Alexander Lata Guacho
1   Endoscopy Unit, Cancer Institute of São Paulo – ICESP, São Paulo, Brazil
,
Leika Miyahara Felipe
2   Anatomopathology Unit, Cancer Institute of São Paulo – ICESP, São Paulo, Brazil
,
Fauze Maluf-Filho
1   Endoscopy Unit, Cancer Institute of São Paulo – ICESP, São Paulo, Brazil
› Institutsangaben Funding None.
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Abstract

Extramedullary plasmacytoma is an immunoproliferative disease of mature B cell that produces immunoglobulins by clonal expansion. Plasma cell neoplasms are responsible for less than 0.1% of all pancreatic masses, they can be primary or secondary to multiple myeloma (MM). We present the case of a 56-year-old man with extramedullary solitary plasmacytoma located in the pancreas, presented with abdominal pain and jaundice. Imaging characteristics are similar to those of other pancreatic diseases, and the diagnosis is confirmed by immunohistochemistry due to the presence of a homogeneous infiltrate of monoclonal plasma cells, which typically express CD38 and CD 138 markers and the presence of kappa/lambda light chains.

Keywords

plasmacytoma - positron emission-tomography computed tomography - endosonography - endoscopic ultrasound-guided fine needle aspiration - immunohistochemistry


Publikationsverlauf

Artikel online veröffentlicht:
29. März 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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