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CC BY 4.0 · Indian J Med Paediatr Oncol 2023; 44(04): 445-448
DOI: 10.1055/s-0042-1759505
Case Report

Triple Trouble: Disseminated Penicilliosis in a Cancer patient with COVID-19

Sujeet Kamtalwar
1   Department of General Medicine, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
2   Homi Bhabha National Institute, Mumbai, India
,
Sumeet Mirgh 
2   Homi Bhabha National Institute, Mumbai, India
3   Department of Medical Oncology, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
,
Ashwini More
1   Department of General Medicine, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
2   Homi Bhabha National Institute, Mumbai, India
,
Anant Gokarn
2   Homi Bhabha National Institute, Mumbai, India
3   Department of Medical Oncology, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
,
Sachin Dhumal
2   Homi Bhabha National Institute, Mumbai, India
4   Department of Radiation Oncology, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
,
Palak Sharma
2   Homi Bhabha National Institute, Mumbai, India
5   Department of Medical Administration, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
,
Sujata Lall
2   Homi Bhabha National Institute, Mumbai, India
6   Department of Microbiology, Advanced Centre for Treatment, Research and Education in cancer, ACTREC, Kharghar, Maharashtra, India
,
Nikhil Patkar 
2   Homi Bhabha National Institute, Mumbai, India
7   Department of Hematolymphoid, Advanced Centre for Treatment, Research and Education in cancer, ACTREC, Kharghar, Maharashtra, India
,
Nitin Shetty
2   Homi Bhabha National Institute, Mumbai, India
8   Department of Radiodiagnosis, Advanced Centre for Treatment, Research and Education in cancer, ACTREC, Kharghar, Maharashtra, India
,
Gaurav Chatterjee
2   Homi Bhabha National Institute, Mumbai, India
9   Department of Hematopathology Laboratory, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
,
Sweta Rajpal 
2   Homi Bhabha National Institute, Mumbai, India
9   Department of Hematopathology Laboratory, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
,
Vivek Bhat
2   Homi Bhabha National Institute, Mumbai, India
6   Department of Microbiology, Advanced Centre for Treatment, Research and Education in cancer, ACTREC, Kharghar, Maharashtra, India
,
Navin Khattry
2   Homi Bhabha National Institute, Mumbai, India
3   Department of Medical Oncology, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
,
Sudeep Gupta 
2   Homi Bhabha National Institute, Mumbai, India
3   Department of Medical Oncology, Advanced Centre for Treatment, Research and Education in Cancer, ACTREC, Kharghar, Maharashtra, India
› Author Affiliations Funding None.
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Abstract

Penicilliosis is a fungal infection caused by the fungus Penicillium marneffei or Talaromyces marneffei. Penicillosis is commonly seen in immunocompromised patients such as in HIV(AIDS). Herein, we present a case of penicilliosis in an oral cavity cancer patient who was admitted for the management of SARS-CoV-2 infection at our hospital. A 50-year-old male patient operated on for squamous cell carcinoma of the oral cavity who completed his adjuvant chemoradiation 2 months ago, presented to our hospital with dry cough for more than 3 weeks. His nasopharyngeal swab was positive for the severe acute respiratory distress syndrome (SARS-CoV-2). During his hospital stay for SARS-CoV-2 infection, he was diagnosed with disseminated penicilliosis. The patient was treated with intravenous antifungals caspofungin and voriconazole. However, he succumbed to disseminated fungal sepsis. This case highlights the need to consider penicilliosis as a possible opportunistic pathogen, especially in immunocompromised patients such as cancer.

Keywords

penicilliosis - cancer - oral cavity - SARS-CoV-2 - COVID-19

Declaration of Patient Consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given his consent for his images and other clinical information to be reported in the journal. The patient understands that his name and initials will not be published and due efforts will be made to conceal his identity, but anonymity cannot be guaranteed.




Publication History

Article published online:
29 March 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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