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Semin Thromb Hemost 2023; 49(03): 234-241
DOI: 10.1055/s-0042-1758060
Review Article

Hemostasis from Bench to Bedside: The History of Three Successful Stories of Translational Medicine

Armando Tripodi
1   Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Fondazione Luigi Villa, Milano, Italy
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Abstract

Looking at the history of hemostasis, one can easily conclude that most of the achievements we see today have been done through the ingenuity and dedication of scientists, who devoted their efforts to translate the basic concepts behind their hypotheses from the laboratory to the patient bedside. I am personally excited by three of these stories. This article aims to review the history on the development of D-dimer, heparin, and coagulometers, which have been chosen as paradigmatic examples of diagnostic testing, drugs, and measuring devices, respectively. They should be considered among the most successful histories of translational medicine.

Keywords

D-dimer - heparin - coagulometers - history


Publication History

Article published online:
17 October 2022

© 2022. Thieme. All rights reserved.

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