Digestive Disease Interventions 2022; 06(04): 317-322
DOI: 10.1055/s-0042-1757764
Review Article

Acute Mesenteric Ischemia: Evaluation, Management, and Interventions

1   Department of Interventional Radiology, Dotter Interventional Institute, Oregon Health Sciences University, Portland, Oregon
› Institutsangaben

Abstract

Acute mesenteric ischemia (AMI) is a dreaded, highly morbid pathology. Often this is due to acute occlusion of the superior mesenteric artery. This can be from thrombus or embolism; however, AMI can also be the result of mesenteric venous thrombus or nonocclusive mesenteric ischemia. There have been many recent advances in diagnosis and treatment including endovascular therapies. While there is increasing data to support an endovascular first approach, with improved 30-day mortality rates and in-hospital mortality, many patients will still require surgical intervention at some point. This article will review AMI for the interventional radiologist including etiologies, diagnosis, and management.



Publikationsverlauf

Eingereicht: 08. August 2022

Angenommen: 07. September 2022

Artikel online veröffentlicht:
20. Oktober 2022

© 2022. Thieme. All rights reserved.

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333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • References

  • 1 Tilsed JV, Casamassima A, Kurihara H. et al. ESTES guidelines: acute mesenteric ischaemia. Eur J Trauma Emerg Surg 2016; 42 (02) 253-270
  • 2 Erben Y, Protack CD, Jean RA. et al. Endovascular interventions decrease length of hospitalization and are cost-effective in acute mesenteric ischemia. J Vasc Surg 2018; 68 (02) 459-469
  • 3 Cokkinis AJ. Mesenteric Vascular Occlusion: Supplemented by an Appendix of 76 Original Cases. London: Bailliere, Tindall and Cox; 1926
  • 4 Björck M, Koelemay M, Acosta S. et al; ESVS Guidelines Committee. Editor's choice - management of the diseases of mesenteric arteries and veins: clinical practice guidelines of the European Society of Vascular Surgery (ESVS). Eur J Vasc Endovasc Surg 2017; 53 (04) 460-510
  • 5 Erben Y, Spaulding AC, Oderich GS. et al. Acute mesenteric ischemia remains a highly morbid diagnosis after initial hospitalization survival. Int J Angiol 2020; 29 (03) 189-195
  • 6 Schoots IG, Koffeman GI, Legemate DA, Levi M, van Gulik TM. Systematic review of survival after acute mesenteric ischaemia according to disease aetiology. Br J Surg 2004; 91 (01) 17-27
  • 7 Kärkkäinen JM. Acute mesenteric ischemia: a challenge for the acute care surgeon. Scand J Surg 2021; 110 (02) 150-158
  • 8 Kärkkäinen JM, Acosta S. Acute mesenteric ischemia (part I) - incidence, etiologies, and how to improve early diagnosis. Best Pract Res Clin Gastroenterol 2017; 31 (01) 15-25
  • 9 Oldenburg WA, Lau LL, Rodenberg TJ, Edmonds HJ, Burger CD. Acute mesenteric ischemia: a clinical review. Arch Intern Med 2004; 164 (10) 1054-1062
  • 10 Endean ED, Barnes SL, Kwolek CJ, Minion DJ, Schwarcz TH, Mentzer Jr RM. Surgical management of thrombotic acute intestinal ischemia. Ann Surg 2001; 233 (06) 801-808
  • 11 Bergqvist D, Svensson PJ. Treatment of mesenteric vein thrombosis. Semin Vasc Surg 2010; 23 (01) 65-68
  • 12 Patel SD, Constantinou J, Hamilton H, Davis M, Ivancev K. Editor's choice - a shaggy aorta is associated with mesenteric embolisation in patients undergoing fenestrated endografts to treat paravisceral aortic aneurysms. Eur J Vasc Endovasc Surg 2014; 47 (04) 374-379
  • 13 Bala M, Kashuk J, Moore EE. et al. Acute mesenteric ischemia: guidelines of the World Society of Emergency Surgery. World J Emerg Surg 2017; 12: 38
  • 14 Liao G, Chen S, Cao H, Wang W, Gao Q. Review: acute superior mesenteric artery embolism: a vascular emergency cannot be ignored by physicians. Medicine (Baltimore) 2019; 98 (06) e14446
  • 15 Klar E, Rahmanian PB, Bücker A, Hauenstein K, Jauch KW, Luther B. Acute mesenteric ischemia: a vascular emergency. Dtsch Arztebl Int 2012; 109 (14) 249-256
  • 16 Bourcier S, Klug J, Nguyen LS. Non-occlusive mesenteric ischemia: diagnostic challenges and perspectives in the era of artificial intelligence. World J Gastroenterol 2021; 27 (26) 4088-4103
  • 17 Al-Diery H, Phillips A, Evennett N, Pandanaboyana S, Gilham M, Windsor JA. The pathogenesis of nonocclusive mesenteric ischemia: implications for research and clinical practice. J Intensive Care Med 2019; 34 (10) 771-781
  • 18 Kolkman JJ, Mensink PB. Non-occlusive mesenteric ischaemia: a common disorder in gastroenterology and intensive care. Best Pract Res Clin Gastroenterol 2003; 17 (03) 457-473
  • 19 Björck M, Wanhainen A. Nonocclusive mesenteric hypoperfusion syndromes: recognition and treatment. Semin Vasc Surg 2010; 23 (01) 54-64
  • 20 Montagnana M, Danese E, Lippi G. Biochemical markers of acute intestinal ischemia: possibilities and limitations. Ann Transl Med 2018; 6 (17) 341
  • 21 van den Heijkant TC, Aerts BA, Teijink JA, Buurman WA, Luyer MD. Challenges in diagnosing mesenteric ischemia. World J Gastroenterol 2013; 19 (09) 1338-1341
  • 22 Pérez-García C, de Miguel Campos E, Fernández Gonzalo A. et al. Non-occlusive mesenteric ischaemia: CT findings, clinical outcomes and assessment of the diameter of the superior mesenteric artery. Br J Radiol 2018; 91 (1081): 20170492
  • 23 Brandt LJ, Boley SJ. American Gastrointestinal Association. AGA technical review on intestinal ischemia. Gastroenterology 2000; 118 (05) 954-968
  • 24 Donaldson JK, Stout BF. Mesenteric thrombosis: (arterial and venous types as separate clinical entities) a clinical and experimental study. Am J Surg 1935; 29: 208-217
  • 25 Dewitte A, Biais M, Coquin J. et al. [Diagnosis and management of acute mesenteric ischemia]. Ann Fr Anesth Reanim 2011; 30 (05) 410-420
  • 26 Aschoff AJ, Stuber G, Becker BW. et al. Evaluation of acute mesenteric ischemia: accuracy of biphasic mesenteric multi-detector CT angiography. Abdom Imaging 2009; 34 (03) 345-357
  • 27 Hawthorn BR, Ratnam LA. Acute mesenteric ischaemia: imaging and intervention. Clin Radiol 2020; 75 (05) 398.e19-398.e28
  • 28 Saranteas T, Kostopanagiotou G, Panou F. Transesophageal echocardiographic examination in the diagnosis of bowel ischemia due to thoracic aorta thrombosis. J Cardiothorac Vasc Anesth 2012; 26 (02) e14-e15
  • 29 Oliva IB, Davarpanah AH, Rybicki FJ. et al. ACR Appropriateness Criteria® imaging of mesenteric ischemia. Abdom Imaging 2013; 38 (04) 714-719
  • 30 Morasch MD, Ebaugh JL, Chiou AC, Matsumura JS, Pearce WH, Yao JS. Mesenteric venous thrombosis: a changing clinical entity. J Vasc Surg 2001; 34 (04) 680-684
  • 31 Cenedese A, Monneuse O, Gruner L, Tissot E, Mennesson N, Barth X. Initial management of extensive mesenteric venous thrombosis: retrospective study of nine cases. World J Surg 2009; 33 (10) 2203-2208
  • 32 Wang MQ, Liu FY, Duan F, Wang ZJ, Song P, Fan QS. Acute symptomatic mesenteric venous thrombosis: treatment by catheter-directed thrombolysis with transjugular intrahepatic route. Abdom Imaging 2011; 36 (04) 390-398
  • 33 Corcos O, Nuzzo A. Gastro-intestinal vascular emergencies. Best Pract Res Clin Gastroenterol 2013; 27 (05) 709-725
  • 34 Sise MJ. Mesenteric ischemia: the whole spectrum. Scand J Surg 2010; 99 (02) 106-110
  • 35 Zettervall SL, Lo RC, Soden PA. et al. Trends in treatment and mortality for mesenteric ischemia in the United States from 2000 to 2012. Ann Vasc Surg 2017; 42: 111-119
  • 36 Najdawi M, Garzelli L, Nuzzo A. et al. Endovascular revascularization of acute arterial mesenteric ischemia: report of a 3-year experience from an intestinal stroke center unit. Eur Radiol 2022; 32 (08) 5606-5615
  • 37 Kärkkäinen JM, Acosta S. Acute mesenteric ischemia (Part II) - vascular and endovascular surgical approaches. Best Pract Res Clin Gastroenterol 2017; 31 (01) 27-38
  • 38 Kärkkäinen JM, Lehtimäki TT, Saari P. et al. Endovascular therapy as a primary revascularization modality in acute mesenteric ischemia. Cardiovasc Intervent Radiol 2015; 38 (05) 1119-1129
  • 39 Fidelman N, AbuRahma AF, Cash BD. et al; Expert Panel on Interventional Radiology. ACR Appropriateness Criteria® radiologic management of mesenteric ischemia. J Am Coll Radiol 2017; 14 (5S): S266-S271
  • 40 Stahl K, Busch M, Maschke SK. et al. A retrospective analysis of nonocclusive mesenteric ischemia in medical and surgical ICU patients: clinical data on demography, clinical signs, and survival. J Intensive Care Med 2020; 35 (11) 1162-1172
  • 41 Clark RA, Gallant TE. Acute mesenteric ischemia: angiographic spectrum. AJR Am J Roentgenol 1984; 142 (03) 555-562
  • 42 Klotz S, Vestring T, Rötker J, Schmidt C, Scheld HH, Schmid C. Diagnosis and treatment of nonocclusive mesenteric ischemia after open heart surgery. Ann Thorac Surg 2001; 72 (05) 1583-1586
  • 43 Ernst S, Luther B, Zimmermann N. et al. [Current diagnosis and therapy of non-occlusive mesenteric ischemia]. Röfo Fortschr Geb Röntgenstr Neuen Bildgeb Verfahr 2003; 175 (04) 515-523
  • 44 Winzer R, Fedders D, Backes M. et al. Local intra-arterial vasodilator infusion in non-occlusive mesenteric ischemia significantly increases survival rate. Cardiovasc Intervent Radiol 2020; 43 (08) 1148-1155
  • 45 Rebelo A, Mammadov M, Partsakhashvili J. et al. Acute and chronic mesenteric ischemia: single center analysis of open, endovascular, and hybrid surgery. BMC Surg 2022; 22 (01) 56
  • 46 Björck M, Acosta S, Lindberg F, Troëng T, Bergqvist D. Revascularization of the superior mesenteric artery after acute thromboembolic occlusion. Br J Surg 2002; 89 (07) 923-927
  • 47 Kougias P, Lau D, El Sayed HF, Zhou W, Huynh TT, Lin PH. Determinants of mortality and treatment outcome following surgical interventions for acute mesenteric ischemia. J Vasc Surg 2007; 46 (03) 467-474
  • 48 Yun WS, Lee KK, Cho J, Kim HK, Huh S. Treatment outcome in patients with acute superior mesenteric artery embolism. Ann Vasc Surg 2013; 27 (05) 613-620
  • 49 Park WM, Gloviczki P, Cherry Jr KJ. et al. Contemporary management of acute mesenteric ischemia: factors associated with survival. J Vasc Surg 2002; 35 (03) 445-452
  • 50 Acosta S, Wadman M, Syk I, Elmståhl S, Ekberg O. Epidemiology and prognostic factors in acute superior mesenteric artery occlusion. J Gastrointest Surg 2010; 14 (04) 628-635
  • 51 Gagnière J, Favrolt G, Alfidja A. et al. Acute thrombotic mesenteric ischemia: primary endovascular treatment in eight patients. Cardiovasc Intervent Radiol 2011; 34 (05) 942-948
  • 52 Blauw JT, Meerwaldt R, Brusse-Keizer M, Kolkman JJ, Gerrits D, Geelkerken RH. Multidisciplinary Study Group of Mesenteric Ischemia. Retrograde open mesenteric stenting for acute mesenteric ischemia. J Vasc Surg 2014; 60 (03) 726-734
  • 53 Hawkins BM, Khan Z, Abu-Fadel MS, Exaire JE, Saucedo JF, Hennebry TA. Endovascular treatment of mesenteric ischemia. Catheter Cardiovasc Interv 2011; 78 (06) 948-952
  • 54 Block TA, Acosta S, Björck M. Endovascular and open surgery for acute occlusion of the superior mesenteric artery. J Vasc Surg 2010; 52 (04) 959-966
  • 55 Swerdlow NJ, Varkevisser RRB, Soden PA. et al. Thirty-day outcomes after open revascularization for acute mesenteric ischemia from the American College of Surgeons National Surgical Quality Improvement Program. Ann Vasc Surg 2019; 61: 148-155
  • 56 Arthurs ZM, Titus J, Bannazadeh M. et al. A comparison of endovascular revascularization with traditional therapy for the treatment of acute mesenteric ischemia. J Vasc Surg 2011; 53 (03) 698-704 , discussion 704–705
  • 57 Salsano G, Salsano A, Sportelli E. et al. What is the best revascularization strategy for acute occlusive arterial mesenteric ischemia: systematic review and meta-analysis. Cardiovasc Intervent Radiol 2018; 41 (01) 27-36
  • 58 Beaulieu RJ, Arnaoutakis KD, Abularrage CJ, Efron DT, Schneider E, Black III JH. Comparison of open and endovascular treatment of acute mesenteric ischemia. J Vasc Surg 2014; 59 (01) 159-164