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CC BY-NC-ND 4.0 · Journal of Digestive Endoscopy 2022; 13(03): 170-178
DOI: 10.1055/s-0042-1754335
Review Article

Future of Metabolic Endoscopy

Rabih Ghazi 
1   Division of Gastroenterology and Hepatology, Mayo Clinic, Minnesota, United States
,
Eric J. Vargas 
1   Division of Gastroenterology and Hepatology, Mayo Clinic, Minnesota, United States
,
Donna Abboud 
1   Division of Gastroenterology and Hepatology, Mayo Clinic, Minnesota, United States
,
Farah Abdul Razak
1   Division of Gastroenterology and Hepatology, Mayo Clinic, Minnesota, United States
,
Tala Mahmoud
1   Division of Gastroenterology and Hepatology, Mayo Clinic, Minnesota, United States
,
Andrew C. Storm
1   Division of Gastroenterology and Hepatology, Mayo Clinic, Minnesota, United States
,
Vinay Chandrasekhara
1   Division of Gastroenterology and Hepatology, Mayo Clinic, Minnesota, United States
,
Barham K. Abu Dayyeh
1   Division of Gastroenterology and Hepatology, Mayo Clinic, Minnesota, United States
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Abstract

Obesity has been escalating as one of the worst public health epidemics. Conservative therapies including lifestyle modifications and weight loss medications have limited efficacy and long-term sustainability. Bariatric surgeries, although effective, remain underutilized due to their cost, safety concerns, and patient acceptance. In the past two decades, endoscopic bariatric and metabolic therapies (EBMTs) have emerged as safe, effective, and less invasive options for the treatment of obesity and its comorbidities, with recent studies reporting favorable outcomes in terms of weight loss and metabolic parameters. This article reviews the major and newly developed EBMTs, with emphasis on their metabolic effects and potential use in the management of metabolic conditions.

Keywords

endoscopic bariatric and metabolic therapies (EBMT) - endoscopic obesity - endoscopic sleeve gastroplasty (ESG) - intragastric balloons (IGB) - metabolic endoscopy - primary obesity surgery endoluminal (POSE)

Authors' Contributions

BKA, RG, and EV were involved in manuscript concept and design.


RG, EV, DA, FA, and TM drafted the manuscript.


BKA, VC, ACS, RG, EV, DA, FA, and TM critically revised the manuscript.




Publication History

Article published online:
13 September 2022

© 2022. Society of Gastrointestinal Endoscopy of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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