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Semin intervent Radiol 2022; 39(03): 304-311
DOI: 10.1055/s-0042-1753481
Review Article

Subclavian Effort Thrombosis: Pathophysiology, Diagnosis, and Management

Matthew Schwenke
1   Department of Radiology, UC Davis School of Medicine, Sacramento, California
,
Roger E. Goldman
1   Department of Radiology, UC Davis School of Medicine, Sacramento, California
,
Amir A. Sarkeshik
2   Department of Surgery, UC Davis School of Medicine, Sacramento, California
,
Eric C. King
1   Department of Radiology, UC Davis School of Medicine, Sacramento, California
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Subclavian Effort Thrombosis: Pathophysiology, Diagnosis, and ManagementSemin intervent Radiol 2022; 39(03): e1-e1
DOI: 10.1055/s-0042-1756698

Abstract

Subclavian vein (SCV) effort thrombosis, also known as Paget-Schroetter syndrome or venous thoracic outlet syndrome, is an uncommon condition that affects individuals with an irregularly narrow thoracic outlet who engage in repetitive overhead motions of the affected arm. Venous injury arises from microtraumas that occur from the repetitive compression of the SCV between the first rib and the overlying clavicle. Additional sources of extrinsic compression can be due to the anterior scalene muscle, subclavius muscle, and costoclavicular ligament. SCV effort thrombosis is a distinct entity from other forms of deep venous thrombosis and requires unique diagnostic and treatment considerations. Early catheter-directed therapy in the form of pharmacomechanical or catheter-directed thrombolysis combined with prompt surgical thoracic outlet decompression offers patients the best chances for early and durable symptom relief.

Keywords

effort thrombosis - Paget-Schroetter - thoracic outlet syndrome - venous thrombosis - chest - thrombolysis - angioplasty - interventional radiology


Publication History

Article published online:
31 August 2022

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