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Synlett 2024; 35(14): 1728-1732
DOI: 10.1055/s-0042-1751550
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Synthesis of Heterodiarylmethanes via Metallaphotoredox Decarboxylative Arylation

Amanda Yanez
a   University of Ottawa, 75 Laurier Ave. E., Ottawa, Ontario, K1N 6N5, Canada
,
Alexandria D. M. Jeanneret∗
b   Paraza Pharma Inc., 2525 Ave. Marie-Curie, Saint Laurent, Québec, H4S 2E1, Canada
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Abstract

A metallaphotoredox-catalyzed synthesis of heterodiarylmethanes using mild reaction conditions, commercially available substrates, and bench-stable catalysts is demonstrated. Moderate yields are obtained, and further derivatization of the newly formed benzylic position is shown.

Key words

metallaphotoredox - decarboxylative arylation - heterodiarylmethanes - photochemistry

Supporting Information

    Supporting information for this article is available online at https://doi.org/10.1055/s-0042-1751550.
  • Supporting Information


Publication History

Received: 04 December 2023

Accepted after revision: 28 December 2023

Article published online:
26 January 2024

© 2024. Thieme. All rights reserved

Georg Thieme Verlag KG
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