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CC BY-NC-ND 4.0 · World J Nucl Med 2022; 21(04): 325-328
DOI: 10.1055/s-0042-1750394
Case Report

Positive 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography 20 Years after Talc Pleurodesis

Supriya A. Bhupathy
1   Department of Medical Education, California University of Science and Medicine, Colton, California, United States
,
Tung V. Huynh
2   Department of Medical Imaging, Arrowhead Regional Medical Center, Colton, California, United States
› Institutsangaben Funding None.
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Abstract

Talc pleurodesis, a frequently performed procedure for refractory pneumothorax or pleural effusion, induces chronic granulomatous inflammation. It can present years later with pleural thickening and markedly increased uptake on positron emission tomography/computed tomography (PET/CT), mimicking the presentation of malignancies. We present the case of a 63-year-old female with positive 18F-fluorodeoxyglucose PET/CT 20 years after talc pleurodesis. Malignancy such as mesothelioma could not initially be ruled out. CT-guided biopsy confirmed an extensive foreign-body giant-cell reaction consistent with talc-related inflammatory change. This case highlights the need for the consideration of talcoma in the differential diagnosis of patients who undergo talc pleurodesis, and is unique in the significant timespan of 20 years between pleurodesis and positive imaging findings.

Keywords

positron emission tomography - computed tomography - 18F-fluorodeoxyglucose - talc pleurodesis - pneumothorax


Publikationsverlauf

Artikel online veröffentlicht:
02. September 2022

© 2022. World Association of Radiopharmaceutical and Molecular Therapy (WARMTH). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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