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DOI: 10.1055/s-0042-1750311
The German Cardiosurgery Atrial Fibrillation Registry: 1-Year Follow-up Outcomes
Funding Statement This work was supported by a grant from AtriCure Europe BV, De I 260, 1101 EE Amsterdam Z. O.

Abstract
Objectives This study of German Cardiosurgery Atrial Fibrillation (CASE-AF) registry aims to describe the 1-year outcomes of patients undergoing ablative procedures for atrial fibrillation (AF) in a cardiosurgical setting.
Methods Between January 2017 and April 2020, 17 German cardiosurgical units enrolled 1,000 consecutive patients undergoing concomitant or stand-alone ablation for AF. In-hospital and 1-year follow-up data were collected on web-based electronic case report forms. The protocol mandated telephone-based follow-up contact after 1 year.
Results At 1-year follow-up (median, 14.5 months [12.6–18.2 months]), significant improvement (p < 0.0001) in baseline modified European Heart Rhythm Association Class I was reported in both concomitant and stand-alone patients. Follow-up examinations were completed in 97.9% of cases, and a sinus rhythm was reported in 60.2 and 63.6% of stand-alone and concomitant patients, respectively. Statistically significant factors determining late recurrence were female gender (p = 0.013), preoperative persistent AF (p < 0.0001), and presence of cardiac implantable electronic device (p = 0.011). All-cause mortality at 1 year was 1% (n = 1) in stand-alone patients and 6.7% (n = 58) in concomitant patients.
Conclusion Surgical ablation of AF is safe and provides satisfactory results at short-term follow-up, with significant improvement in patient symptoms. Adequate cardiac rhythm monitoring should be prioritized for higher quality data acquisition.
Note
ClinicalTrials.gov Identifier: NCT03091452. https://clinicaltrials.gov/ct2/show/NCT03091452.
Publikationsverlauf
Eingereicht: 13. März 2022
Angenommen: 12. Mai 2022
Artikel online veröffentlicht:
27. Juli 2022
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