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Semin Respir Crit Care Med 2022; 43(04): 541-551
DOI: 10.1055/s-0042-1747938
Review Article

Bronchoscopic Lung Volume Reduction for Emphysema: Review and Update

Theodoor David Koster
1   Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
,
Marlies Van Dijk
1   Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
,
Dirk-Jan Slebos
1   Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Abstract

In carefully selected patients with severe chronic obstructive pulmonary disease, characterized by emphysema and hyperinflation, lung volume reduction is an option to reduce lung hyperinflation, improve lung function, quality of life, and exercise capacity. Currently, there are several bronchoscopic and surgical treatment options to achieve lung volume reduction. It is important to carefully phenotype these patients, to select the optimal treatment option, with consideration of possible adverse events or contraindications, and it is highly recommended to discuss these treatment strategies in a multidisciplinary team. The treatment with one-way endobronchial valves has been investigated most extensively and more data are available regarding the treatment of more “marginal cases,” or subsequent lung volume reduction surgery. Other bronchoscopic lung volume reduction options include treatment with coils, thermal vapor ablation, and sclerosant agents. In this review, we aim to summarize the current clinical evidence on the bronchoscopic lung volume reduction therapies and important aspects regarding optimal patient selection.

Keywords

bronchoscopic lung volume reduction - lung volume reduction surgery - emphysema - COPD - endobronchial valves - patient selection


Publication History

Article published online:
13 May 2022

© 2021. Thieme. All rights reserved.

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