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Exp Clin Endocrinol Diabetes 2016; 124(10): 597-601
DOI: 10.1055/s-0042-111044
Article
© Georg Thieme Verlag KG Stuttgart · New York

High Intensity Interval Training Reduces the Levels of Serum Inflammatory Cytokine on Women with Metabolic Syndrome

F. M. Steckling
1   Departamento de Métodos e Técnicas Desportivas, Centro de Educação Física e Desportos, Universidade Federal de Santa Maria, Brazil
3   Departamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Brazil
,
J. B. Farinha
1   Departamento de Métodos e Técnicas Desportivas, Centro de Educação Física e Desportos, Universidade Federal de Santa Maria, Brazil
7   Escola superior de Educação Física, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
,
D. L. D. Santos
1   Departamento de Métodos e Técnicas Desportivas, Centro de Educação Física e Desportos, Universidade Federal de Santa Maria, Brazil
,
G. Bresciani
2   Grupo de Investigación en Rendimiento Físico y Salud (IRyS), Escuela de Educación Física, Pontificia Universidad Católica de Valparaiso, Valparaiso, Chile
,
J. A. Mortari
1   Departamento de Métodos e Técnicas Desportivas, Centro de Educação Física e Desportos, Universidade Federal de Santa Maria, Brazil
,
S. T. Stefanello
3   Departamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Brazil
,
A. A. Courtes
3   Departamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Brazil
,
T. Duarte
5   Programa de Pós-Graduação em Farmacologia, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Santa Maria, Brazil
,
M. M. M. F. Duarte
6   Universidade Luterana do Brazil, Brazil
,
R. N. Moresco
4   Departamento de Análises Clinicas e Toxicológicas, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Brazil
,
M. S. Cardoso
4   Departamento de Análises Clinicas e Toxicológicas, Centro de Ciências da Saúde, Universidade Federal de Santa Maria, Brazil
,
F. A.A. Soares
3   Departamento de Bioquímica e Biologia Molecular, Centro de Ciências Naturais e Exatas, Universidade Federal de Santa Maria, Brazil
› Author Affiliations
Further Information

Publication History

received 02 February 2016
first decision 20 June 2016

accepted 22 June 2016

Publication Date:
22 September 2016 (online)

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Abstract

Objectives: This study investigate the effects of a high intensity interval training (HIIT) and 2 weeks of detraining in functional and body composition parameters, lipoproteins, glucose metabolismand inflammation markers in postmenopausal women with metabolic syndrome (MS).

Design: 17 untrained women with MS underwent a HIIT program for 12 weeks.

Methods: The training was performed in treadmills, 3 days per week, with intensity ranging from 70–90% of the maximum heart rate (HRmax) and 2 weeks untrained (inactive). Functional and body composition parameters were evaluated before and after the training, while maximal oxygen uptake, lipoprotein and inflammation markers were analyzed before, after training and also in detraining.

Results: The HITT program resulted in changesparameters as glucose, HbA1cand NOx after training. In addition, a reduction in pro-inflammatory interleukins and an increase in IL-10 after the HIIT program were found. However, an increase in plasma levels of lipoprotein was found and body composition parameters remain unaltered.Besides, only 2 weeks of detraining are able to revert the effects on inflammatory parameters afforded by the HIIT program.

Conclusions: The HIIT program used here positively affected inflammatory profile and other parameters, as glucose, HbA1cand NOx, on postmenopausal women with MS. Moreover, 2 weeks of detraining can reverse the beneficial effects of HIIT program. Our results point out the necessity to aply acontinuous HITT program, in order maintain the benefits detected, to post menopausal women with MS.

Key words

metabolic syndrome - inflammation - high intensity interval training - detraining
 

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