Subscribe to RSS
DOI: 10.1055/s-0042-103271
Klinische Präsentation des Lungenkarzinoms – Epidemiologie, Komorbidität, funktionelle und bildgebende Diagnostik
Clinical presentation of lung cancer – Epidemiology, co-morbidities, functional evaluation, diagnostic imagingPublication History
Publication Date:
08 April 2016 (online)
![](https://www.thieme-connect.de/media/klinikarzt/201603/lookinside/thumbnails/ka_03_2016_05_10-1055-s-0042-103271-1.jpg)
Das Lungenkarzinom ist in Deutschland bei den Männern der häufigste Tumor. Ca. 40 000 Menschen sterben pro Jahr in Deutschland daran. Da das Lungenkarzinom in den frühen Stadien häufig asymptomatisch verläuft, wird es häufig erst in fortgeschrittenen Stadien diagnostiziert. Das Zigarettenrauchen stellt den größten Risikofaktor dar. Neben anderen Kanzerogenen stellen die COPD und die Lungenfibrose einen Risikofaktor für die Entwicklung eines Lungenkarzinoms dar. Es werden die bildgebenden Verfahren in der Diagnostik des Lungenkarzinoms dargestellt und im Rahmen der funktionellen Diagnostik wird beschrieben, wie eine präoperative Evaluation durchgeführt wird.
Lung cancer is the major site of cancer in men in Germany. Lung cancer is by far the leading cause of cancer-related death worldwide. The mortality is about 40 000 people in Germany per year. Symptoms usually reflect a manifestation of advanced disease. Lung cancer is related to smoking. The incidence rate of lung cancer in smokers with COPD is higher compared in smokers without COPD. Fibrosis of the lung seems to be as well a comorbidity. The article describes diagnostic imaging in lung cancer and the pre-operative pulmonary evaluation of lung cancer patients.
-
Literatur
- 1 Alberts WM. Introduction: Diagnosis and Management of Lung Cancer. ACCP Guidelines. Chest 2007; 132: 205-225
- 2 Köhler D, Schönhofer B, Voshaar T. Thorakale Tumoren. Pneumologie, Ein Leitfaden für rationales Handeln in Klinik und Praxis. Thieme Verlag 2015; 288-328
- 3 Alberg AJ, Ford JG, Samet JM. Epidemiology of Lung Cancer. ACCP Guidelines. Chest 2007; 132: 29-35
- 4 Lin H, Huang Y, Yan H et al. A family history pf cancer and lung cancer rick in never-smokers: clinic-based case-control study. Lung Cancer 2015; 89: 94-98
- 5 Vansteenkiste J, Derijcke S, Hantson I. Lung cancer: diagnosis and staging. In: Palange P, Simonds AK. ERS Handbook, Respiratory Medicine: The European Respiratory Society. 2013: 455-459
- 6 Navani N, Spiro SG. Symptoms and signs of lung cancer. In: Spiro SG, Huber RM, Janes SM, eds. Thoracic Malignancies. Eur Respir Monogr; 2009. 45. 71-87
- 7 Spiro SG, Gould MK, Colice GL. Initial Evaluation of the Patient With Lung Cancer: Symptoms, Signs, Laboratory Tests, and Paraneoplastic Syndromes. ACCP Guidelines. Chest 2007; 132: 1495-1605
- 8 de-Torres JP, Zulueta JJ. The association with COPD. European Respiratory Monograph: Lung Cancer. The European Respiratory Society 2015; 45-56
- 9 Durham AL, Adcock LM. The relationship between COPD and lung cancer. Lung Cancer 2015; 90: 121-127
- 10 Cordeiro CR, Alfaro TM, Freitas A, Cemlyn-Jones J. Idiopathic pulmonary fibrosis. European Respiratory Monograph: Lung Cancer. The European Respiratory Society 2015; 57-70
- 11 Zanwjk van N. Aetiology and prevention of lung cancer. European Respiratory Monograph 17: Lung Cancer. The European Respiratory Society 2001; 13-33
- 12 Van Tilburg PMB, Stam H, Hoogsteden HC, van Klaveren RJ. Pre-operative pulmonary evaluation of lung cancer patients: a review of the literature. Eur Respir J 2009; 33: 1206-1215
- 13 Charloux A. Fitness for radical treatment of lung cancer patients. Breathe 2011; 3: 221-228
- 14 Brunelle A, Charloux A, Bolliger CT et al. ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemotherapy). Eur Respir J 2009; 34: 17-41
- 15 Bolliger CT, Perruchoud AP. Functional evaluation of the lung resection candidate. Eur Respir J 1998; 11: 198-212
- 16 Goeckenjan G et al. Prevention, Diagnosis, Therapy, and Follow-up of Lung Cancer. Pneumologie 2011; 65: 39-59
- 17 Dietrich CF, Annema JT, Clementsen P et al. Ultrasound techniques in the evaluation of the mediastinum, part I: endoscopic ultrasound (EUS), endobronchial ultrasound (EBUS) and transcutaneous mediastinal ultrasound (TMUS), introduction into ultrasound techniques. J Thorac Dis 2015; 7
- 18 Poullis M, McShane J, Shaw M et al. Lung cancer staging: a physiological update. Interactive CardioVascular and Thoracic Surgery 2012; 14: 743-749
- 19 De Leyn P, Dooms C, Kuzdzal J et al. Preoperative mediastinal lymph node staging for non-small cell lung cancer: 2014 update of the 2007 ESTS guidelines. Transl Lung Cancer Rv 2014; 3: 225-233