Osteologie 2021; 30(04): 340
DOI: 10.1055/s-0041-1736726
Abstract

Involvement of tissue non-specific alkaline phosphatase in adipogenic program of bone marrow adipose tissue cells

A Schiminski
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
,
K Horas
3   Chair for Orthopedics, University of Würzburg
,
J Ilic
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
,
B Schlierf
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
,
M Rudert
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
3   Chair for Orthopedics, University of Würzburg
,
M Herrmann
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
,
D Trivanovic
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
› Author Affiliations
› Further Information
Also available at
 

Introduction

Accumulation of bone marrow adipose tissue (MAT) within bone during life interferes with bone health as well as systemic metabolism. We here investigated the implication of tissue non-specific alkaline phosphatase (TNAP) in MAT-derived cell differentiation.



Publication History

Article published online:
04 November 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag
Rüdigerstraße 14, 70469 Stuttgart, Germany