Osteologie 2021; 30(04): 340
DOI: 10.1055/s-0041-1736726
Abstract

Involvement of tissue non-specific alkaline phosphatase in adipogenic program of bone marrow adipose tissue cells

A Schiminski
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
,
K Horas
3   Chair for Orthopedics, University of Würzburg
,
J Ilic
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
,
B Schlierf
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
,
M Rudert
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
3   Chair for Orthopedics, University of Würzburg
,
M Herrmann
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
,
D Trivanovic
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Bernhard-Heine-Center for Locomotion Research, University of Würzburg
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Introduction

Accumulation of bone marrow adipose tissue (MAT) within bone during life interferes with bone health as well as systemic metabolism. We here investigated the implication of tissue non-specific alkaline phosphatase (TNAP) in MAT-derived cell differentiation.



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Artikel online veröffentlicht:
04. November 2021

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