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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2022; 12(02): 186-190
DOI: 10.1055/s-0041-1736269
Review Article

Clinical Application of Platelet-Rich Fibrin in Pediatric Dentistry

Sowndarya Gunasekaran 
1   Department of Paediatrics and Preventive Dentistry, Vinayaka Mission's Sankarachariyar Dental College, Vinayaka Mission's Research Foundation Deemed to be University, Ariyanoor, Salem, India
,
Soundarya Sakthivel 
2   Department of Oral Medicine and Radiology, AB Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, India
,
Shanthala B. M. 
3   Department of Paediatrics and Preventive Dentistry, Coorg Institute of Dental Sciences, Kodagu, Karnataka, India
,
George Babu 
3   Department of Paediatrics and Preventive Dentistry, Coorg Institute of Dental Sciences, Kodagu, Karnataka, India
,
Vidhya Vijayan 
3   Department of Paediatrics and Preventive Dentistry, Coorg Institute of Dental Sciences, Kodagu, Karnataka, India
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Abstract

Platelet-rich fibrin (PRF) is a fibrin matrix in which platelet cytokines, growth factors, and cells are trapped and may be released after a certain time and that can serve as a resorbable membrane. It can be obtained from blood with the help of a simple process. PRF is basically a concentrate of growth factors that promote wound healing and regeneration, which is used in various disciplines of dentistry to repair various lesions and regenerate dental and oral tissues. Although the use of PRF is well-documented, its use in pediatric dentistry remains unexplored, due to its restrictions and on account of the fact that it is a blood-derived product. PRF has been used globally to enhance tissue healing. This article provides an insight into the use of PRF in pediatric dentistry, its benefits, limitations, and recommendations.

Keywords

apexogenesis - direct pulp capping - regenerative endodontics - scaffolds - platelet-rich plasma

Authors' Contributions

All the authors contributed equally to the study. S.G. made substantial contributions to conception and design and was involved in drafting the manuscript and revising it critically for important intellectual content. S.S. made substantial contributions to conception and design, acquisition of data, and analysis and interpretation of data, besides providing the final approval of the version to be published. S.B.M. made substantial contributions to conception and design, acquisition of data, analysis and interpretation of data, besides providing the final approval of the version to be published. G.B. made substantial contributions to conception and design and revised it critically for important intellectual content. V.V. made substantial contributions to conception and design and revised it critically for important intellectual content.




Publication History

Article published online:
24 October 2021

© 2021. Nitte (Deemed to be University). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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