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Clin Colon Rectal Surg 2021; 34(06): 426-430
DOI: 10.1055/s-0041-1735275
Review Article

Special Considerations of Anastomotic Leak in Patients with Rectal Cancer

Christy E. Cauley
1   Department of General and Gastrointestinal Surgery, Massachusetts General Hospital, Boston, Massachusetts
,
Matthew F. Kalady
2   Division of Colon and Rectal Surgery, The Ohio State University, Columbus, OH
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Abstract

Anastomotic leak in patients with rectal cancer has the potential to cause worse oncologic outcomes in addition to major morbidity and mortality risk of this dreaded complication. Anatomic location of the rectal cancer determines the ability to perform a restorative operation and the height of the anastomosis in relation to the anal canal. Clinical staging dictates the need for neoadjuvant treatment (such as chemotherapy and radiation) which may also contribute to anastomotic leak risk. In addition to oncologic outcomes, anastomotic leak can impact bowel function, the need for permanent stoma, and long-term quality of life. This study will discuss special considerations for anastomotic leak prevention and clinical implications of this complication in patients with rectal cancer.

Keywords

rectal cancer - anastomotic leak - function - oncologic outcome


Publication History

Article published online:
23 November 2021

© 2021. Thieme. All rights reserved.

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