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Clin Colon Rectal Surg 2021; 34(06): 379-384
DOI: 10.1055/s-0041-1735268
Review Article

New Technologies to Prevent Anastomotic Leak

Abhineet Uppal
1   Division of Colorectal Surgery, Department of Surgery, University of California at Irvine Medical Center, Orange, California
,
Alessio Pigazzi
1   Division of Colorectal Surgery, Department of Surgery, University of California at Irvine Medical Center, Orange, California
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Abstract

Leaks from anastomoses can be a serious complication of any gastrointestinal resection. Leaks lead to increased morbidity, delayed postoperative recovery, and potential delays in adjuvant treatment in cancer cases. Prevention of anastomotic leak has been an area of ongoing research for decades. Methods of assessing bowel perfusion have been developed that may provide forewarning of anastomotic compromise. Physical reinforcement of the anastomosis with buttressing material is an available method employed with the goal of preventing leaks. Liquid-based sealants have also been explored. Lastly, interactions between the gut microbiome and anastomotic healing have been investigated as a mean of manipulating the microenvironment to reduce leak rates. Though no single technology has been successful in eliminating leaks, an understanding of these developing fields will be important for all surgeons who operate on the gastrointestinal tract.

Keywords

anastomosis - colorectal surgery - anastomotic leak - bowel perfusion - endoscopy


Publication History

Article published online:
23 November 2021

© 2021. Thieme. All rights reserved.

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