RSS-Feed abonnieren

DOI: 10.1055/s-0041-1734354
Hydrogen Peroxide Poisoning—A Rare Cause of Portal Venous Gas

Abstract
Hydrogen peroxide is a clear and odorless liquid at room temperature that can easily be mistaken for water. Its ingestion results in varied clinical and radiological squeals depending on the volume and concentration of the liquid. We present a case of a 22-year-old lady who accidentally ingested 30 to 40 mL of 3% hydrogen peroxide and presented with hematemesis and abdominal pain. On further radiological evaluation, she was found to have portal venous gas and pneumatosis of the bowel wall. She was conservatively managed with 100% oxygen and nil per os for 2 days following which the portal venous gas resolved. Hydrogen peroxide ingestion causes a massive release of oxygen and when its volume exceeds its solubility in blood, gas embolism occurs that is responsible for portal venous gas and pneumatosis. Close monitoring with conservative management will suffice in mild cases without the need for any therapeutic intervention.
Publikationsverlauf
Artikel online veröffentlicht:
28. Juli 2021
© 2021. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India
-
References
- 1 Urban MV, Rath T, Radtke C. Hydrogen peroxide (H2O2): a review of its use in surgery. Wien Med Wochenschr 2019; 169 (9-10) 222-225
- 2 Youssef EW, Chukwueke VS, Elsamaloty L, Moawad S, Elsamaloty H. Accidental concentrated hydrogen peroxide ingestion associated with portal venous gas. J Radiol Case Rep 2018; 12 (08) 12-16
- 3 Papafragkou S, Gasparyan A, Batista R, Scott P. Treatment of portal venous gas embolism with hyperbaric oxygen after accidental ingestion of hydrogen peroxide: a case report and review of the literature. J Emerg Med 2012; 43 (01) e21-e23
- 4 Finnegan M, Linley E, Denyer SP, McDonnell G, Simons C, Maillard JY. Mode of action of hydrogen peroxide and other oxidizing agents: differences between liquid and gas forms. J Antimicrob Chemother 2010; 65 (10) 2108-2115
- 5 Watt BE, Proudfoot AT, Vale JA. Hydrogen peroxide poisoning. Toxicol Rev 2004; 23 (01) 51-57
- 6 Kesarwani V, Ghelani DR, Reece G. Hepatic portal venous gas: a case report and review of literature. Indian J Crit Care Med 2009; 13 (02) 99-102
- 7 Sebastià C, Quiroga S, Espin E, Boyé R, Alvarez-Castells A, Armengol M. Portomesenteric vein gas: pathologic mechanisms, CT findings, and prognosis. Radiographics 2000; 20 (05) 1213-1224
- 8 Dunbar EM, Fox R, Watson B, Akrill P. Successful late treatment of venous air embolism with hyperbaric oxygen. Postgrad Med J 1990; 66 (776) 469-470