CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2021; 31(02): 391-399
DOI: 10.1055/s-0041-1734223
Review Article

Image-Guided Breast Interventions: Biopsy and Beyond

1   Department of Radiodiagnosis, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
,
Rashmi Singh
1   Department of Radiodiagnosis, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
,
Seema Mishra
2   Department of Oncoanaesthesia & Palliative Medicine, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
,
Smriti Hari
1   Department of Radiodiagnosis, Dr. B.R.A. Institute Rotary Cancer Hospital, All India Institute of Medical Sciences, New Delhi, India
› Author Affiliations

Abstract

Breast interventions primarily comprise of biopsy of the suspicious breast lesions to obtain accurate pathological diagnosis. Generally, image-guided breast biopsy is required for nonpalpable lesions, however, even in palpable lesions, image-guided biopsy should be performed as it improves the accuracy of diagnosis. Image-guided breast interventions have progressed well beyond biopsy, making the radiologist an important part of the multidisciplinary management of breast cancer. Preoperative localization of nonpalpable abnormalities guides optimal surgical excision to obtain negative margins without sacrificing the normal tissue. Ablative procedures for breast cancer treatment such as radiofrequency ablation (RFA) and high-intensity focused ultrasound ablation can sometimes replace surgery in older patients with comorbidities. This article enumerates and describes the expanding spectrum of image-guided interventions performed by breast radiologist.



Publication History

Article published online:
28 July 2021

© 2021. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 
  • References

  • 1 GLOBACON 2020. Global Health Observatory. Geneva: World Health Organization. Available at: https://gco.iarc.fr/today/data/factsheets/populations/356-india-fact-sheets.pdf. Accessed July 23, 2021
  • 2 Bray F, McCarron P, Parkin DM. The changing global patterns of female breast cancer incidence and mortality. Breast Cancer Res 2004; 6 (06) 229-239
  • 3 Hari S, Kumari S, Srivastava A, Thulkar S, Mathur S, Veedu PT. Image guided versus palpation guided core needle biopsy of palpable breast masses: a prospective study. Indian J Med Res 2016; 143 (05) 597-604
  • 4 Teshome M, Hunt KK. Neoadjuvant therapy in the treatment of breast cancer. Surg Oncol Clin N Am 2014; 23 (03) 505-523
  • 5 Collaço LM, de Lima RS, Werner B, Torres LF. Value of fine needle aspiration in the diagnosis of breast lesions. Acta Cytol 1999; 43 (04) 587-592
  • 6 Parker SH, Jobe WE, Dennis MA. et al. US-guided automated large-core breast biopsy. Radiology 1993; 187 (02) 507-511
  • 7 Burbank F, Parker SH, Fogarty TJ. Stereotactic breast biopsy: improved tissue harvesting with the Mammotome. Am Surg 1996; 62 (09) 738-744
  • 8 Jackman RJ, Marzoni Jr FA, Rosenberg J. False-negative diagnoses at stereotactic vacuum-assisted needle breast biopsy: long-term follow-up of 1,280 lesions and review of the literature. AJR Am J Roentgenol 2009; 192 (02) 341-351
  • 9 Zhang C, Lewis DR, Nasute P, Hayes M, Warren LJ, Gordon PB. The negative predictive value of ultrasound-guided 14-gauge core needle biopsy of breast masses: a validation study of 339 cases. Cancer Imaging 2012; 12: 488-496
  • 10 Lee SH, Kim E-K, Kim MJ, Moon HJ, Yoon JH. Vacuum-assisted breast biopsy under ultrasonographic guidance: analysis of a 10-year experience. Ultrasonography 2014; 33 (04) 259-266
  • 11 Huang ML, Adrada BE, Candelaria R, Thames D, Dawson D, Yang WT. Stereotactic breast biopsy: pitfalls and pearls. Tech Vasc Interv Radiol 2014; 17 (01) 32-39
  • 12 Schrading S, Distelmaier M, Dirrichs T. et al. Digital breast tomosynthesis-guided vacuum-assisted breast biopsy: initial experiences and comparison with prone stereotactic vacuum-assisted biopsy. Radiology 2015; 274 (03) 654-662
  • 13 Rochat CJ, Baird GL, Lourenco AP. Digital mammography stereotactic biopsy versus digital breast tomosynthesis-guided biopsy: differences in biopsy targets, pathologic results, and discordance rates. Radiology 2020; 294 (03) 518-527
  • 14 Bahl M, Maunglay M, D’Alessandro HA, Lehman CD. Comparison of upright digital breast tomosynthesis-guided versus prone stereotactic vacuum-assisted breast biopsy. Radiology 2019; 290 (02) 298-304
  • 15 Carrara GF, Scapulatempo-Neto C, Abrahão-Machado LF. et al. Breast-conserving surgery in locally advanced breast cancer submitted to neoadjuvant chemotherapy. Safety and effectiveness based on ipsilateral breast tumor recurrence and long-term follow-up. Clinics (São Paulo 2017; 72 (03) 134-142
  • 16 Baron LF, Baron PL, Ackerman SJ, Durden DD, Pope Jr TL. Sonographically guided clip placement facilitates localization of breast cancer after neoadjuvant chemotherapy. AJR Am J Roentgenol 2000; 174 (02) 539-540
  • 17 Pennisi A, Kieber-Emmons T, Makhoul I, Hutchins L. Relevance of pathological complete response after neoadjuvant therapy for breast cancer. Breast Cancer (Auckl 2016; 10: 103-106
  • 18 Margolin FR, Kaufman L, Denny SR, Jacobs RP, Schrumpf JD. Metallic marker placement after stereotactic core biopsy of breast calcifications: comparison of two clips and deployment techniques. AJR Am J Roentgenol 2003; 181 (06) 1685-1690
  • 19 Espinosa-Bravo M, Sao Avilés A, Esgueva A. et al. Breast conservative surgery after neoadjuvant chemotherapy in breast cancer patients: comparison of two tumor localization methods. Eur J Surg Oncol 2011; 37 (12) 1038-1043
  • 20 Alonso-Bartolome P, Ortega Garcia E, Garijo Ayensa F, de Juan Ferre A, Vega Bolivar A. Utility of the tumor bed marker in patients with breast cancer receiving induction chemotherapy. Acta Radiol 2002; 43 (01) 29-33
  • 21 Braeuning MP, Burke ET, Pisano ED. Embolization coils as tumor markers for mammography in patients undergoing neoadjuvant chemotherapy for carcinoma of the breast. AJR Am J Roentgenol 2000; 174 (01) 251-252
  • 22 Zhang Y, Seely J, Cordeiro E. et al. Radioactive seed localization versus wire-guided localization for nonpalpable breast cancer: a cost and operating room efficiency analysis. Ann Surg Oncol 2017; 24 (12) 3567-3573
  • 23 Hayes MK. Update on preoperative breast localization. Radiol Clin North Am 2017; 55 (03) 591-603
  • 24 Oh JL, Nguyen G, Whitman GJ. et al. Placement of radiopaque clips for tumor localization in patients undergoing neoadjuvant chemotherapy and breast conservation therapy. Cancer 2007; 110 (11) 2420-2427
  • 25 Kirstein LJ, Rafferty E, Specht MC. et al. Outcomes of multiple wire localization for larger breast cancers: when can mastectomy be avoided?. J Am Coll Surg 2008; 207 (03) 342-346
  • 26 Liberman L, Kaplan J, Van Zee KJ. et al. Bracketing wires for preoperative breast needle localization. AJR Am J Roentgenol 2001; 177 (03) 565-572
  • 27 Demiral G, Senol M, Bayraktar B, Ozturk H, Celik Y, Boluk S. Diagnostic value of hook wire localization technique for non-palpable breast lesions. J Clin Med Res 2016; 8 (05) 389-395
  • 28 Bronstein AD, Kilcoyne RF, Moe RE. Complications of needle localization of foreign bodies and nonpalpable breast lesions. Arch Surg 1988; 123 (06) 775-779
  • 29 Corsi F, Sorrentino L, Bossi D, Sartani A, Foschi D. Preoperative localization and surgical margins in conservative breast surgery. Int J Surg Oncol 2013; 2013: 793819
  • 30 Hughes JH, Mason MC, Gray RJ. et al. A multi-site validation trial of radioactive seed localization as an alternative to wire localization. Breast J 2008; 14 (02) 153-157
  • 31 Pavlicek W, Walton HA, Karstaedt PJ, Gray RJ. Radiation safety with use of I-125 seeds for localization of nonpalpable breast lesions. Acad Radiol 2006; 13 (07) 909-915
  • 32 Sharek D, Zuley ML, Zhang JY, Soran A, Ahrendt GM, Ganott MA. Radioactive seed localization versus wire localization for lumpectomies: a comparison of outcomes. AJR Am J Roentgenol 2015; 204 (04) 872-877
  • 33 Harvey JR, Lim Y, Murphy J. et al. Safety and feasibility of breast lesion localization using magnetic seeds (Magseed): a multi-centre, open-label cohort study. Breast Cancer Res Treat 2018; 169 (03) 531-536
  • 34 Rahusen FD, Bremers AJ, Fabry HF. van Amerongen AH, Boom RP, Meijer S. Ultrasound-guided lumpectomy of nonpalpable breast cancer versus wire-guided resection: a randomized clinical trial. Ann Surg Oncol 2002; 9 (10) 994-998
  • 35 Hu X, Li S, Jiang Y. et al. Intraoperative ultrasound-guided lumpectomy versus wire-guided excision for nonpalpable breast cancer. J Int Med Res 2020 48(1)300060519896707
  • 36 Krekel NM, Haloua MH, Lopes Cardozo AM. et al. Intraoperative ultrasound guidance for palpable breast cancer excision (COBALT trial): a multicentre, randomised controlled trial. Lancet Oncol 2013; 14 (01) 48-54
  • 37 Vispute T, Seenu V, Parshad R, Hari S, Thulkar S, Mathur S. Suhani. Comparison of resection margins and cosmetic outcome following intraoperative ultrasound-guided excision versus conventional palpation-guided breast conservation surgery in breast cancer: a randomized controlled trial. Indian J Cancer 2018; 55 (04) 361-365
  • 38 Rinaldi P, Ierardi C, Costantini M. et al. Cystic breast lesions: sonographic findings and clinical management. J Ultrasound Med 2010; 29 (11) 1617-1626
  • 39 Gomes C, Amaral N, Marques C. Borralho R, de Oliveira CF. Sclerosis of gross cysts of the breast: a three-year study. Eur J Gynaecol Oncol 2002; 23 (03) 191-194
  • 40 Gizienski T-A, Harvey JA, Sobel AH. Breast cyst recurrence after postaspiration injection of air. Breast J 2002; 8 (01) 34-37
  • 41 Özgen A. Effectiveness of single-session ultrasound-guided percutaneous ethanol sclerotherapy in simple breast cysts. Diagn Interv Radiol 2016; 22 (03) 220-223
  • 42 Imperiale A, Zandrino F, Calabrese M, Parodi G, Massa T. Abscesses of the breast. US-guided serial percutaneous aspiration and local antibiotic therapy after unsuccessful systemic antibiotic therapy. Acta Radiol 2001; 42 (02) 161-165
  • 43 Ulitzsch D, Nyman MKG, Carlson RA. Breast abscess in lactating women: US-guided treatment. Radiology 2004; 232 (03) 904-909
  • 44 Trop I, Dugas A, David J. et al. Breast abscesses: evidence-based algorithms for diagnosis, management, and follow-up. Radiographics 2011; 31 (06) 1683-1699
  • 45 Hahn M, Krainick-Strobel U, Toellner T. et al. Minimally Invasive Breast Intervention Study Group (AG MiMi) of the German Society of Senology (DGS), Study Group for Breast Ultrasonography of the German Society for Ultrasound in Medicine (DEGUM). Interdisciplinary consensus recommendations for the use of vacuum-assisted breast biopsy under sonographic guidance: first update 2012. Ultraschall Med 2012; 33 (04) 366-371
  • 46 Yom CK, Moon BI, Choe KJ, Choi HY, Park YL. Long-term results after excision of breast mass using a vacuum-assisted biopsy device. ANZ J Surg 2009; 79 (11) 794-798
  • 47 Wang ZL, Li JL, Su L, Zhang YF, Tang J. An evaluation of a 10-gauge vacuum-assisted system for ultrasound-guided excision of clinically benign breast lesions. Breast 2009; 18 (03) 192-196
  • 48 Krainick-Strobel U, Huber B, Majer I. et al. Complete extirpation of benign breast lesions with an ultrasound-guided vacuum biopsy system. Ultrasound Obstet Gynecol 2007; 29 (03) 342-346
  • 49 Luo HJ, Chen X, Tu G, Wang J, Wu CY, Yang GL. Therapeutic application of ultrasound-guided 8-gauge Mammotome system in presumed benign breast lesions. Breast J 2011; 17 (05) 490-497
  • 50 Burak WE Jr, Agnese DM, Povoski SP. et al. Radiofrequency ablation of invasive breast carcinoma followed by delayed surgical excision. Cancer 2003; 98 (07) 1369-1376
  • 51 Kinoshita T, Iwamoto E, Tsuda H, Seki K. Radiofrequency ablation as local therapy for early breast carcinomas. Breast Cancer 2011; 18 (01) 10-17
  • 52 Ito T, Oura S, Nagamine S. et al. Radiofrequency ablation of breast cancer: a retrospective study. Clin Breast Cancer 2018; 18 (04) e495-e500
  • 53 Palussière J, Henriques C, Mauriac L. et al. Radiofrequency ablation as a substitute for surgery in elderly patients with nonresected breast cancer: pilot study with long-term outcomes. Radiology 2012; 264 (02) 597-605
  • 54 Chen J, Zhang C, Li F. et al. A meta-analysis of clinical trials assessing the effect of radiofrequency ablation for breast cancer. OncoTargets Ther 2016; 9: 1759-1766
  • 55 Nguyen T, Hattery E, Khatri VP. Radiofrequency ablation and breast cancer: a review. Gland Surg 2014; 3 (02) 128-135
  • 56 Hoover S, Bloom E, Patel S. Review of breast conservation therapy: then and now. ISRN Oncol 2011; 2011: 617593
  • 57 Vicini F, Beitsch P, Quiet C. et al. Five-year analysis of treatment efficacy and cosmesis by the American Society of Breast Surgeons MammoSite Breast Brachytherapy Registry Trial in patients treated with accelerated partial breast irradiation. Int J Radiat Oncol Biol Phys 2011; 79 (03) 808-817
  • 58 Roberts ME, Neville E, Berrisford RG, Antunes G, Ali NJ. BTS Pleural Disease Guideline Group. Management of a malignant pleural effusion: British Thoracic Society pleural disease guideline 2010. Thorax 2010; 65 (Suppl. 02) ii32-ii40
  • 59 Fysh ETH, Tremblay A, Feller-Kopman D. et al. Clinical outcomes of indwelling pleural catheter-related pleural infections: an international multicenter study. Chest 2013; 144 (05) 1597-1602
  • 60 Bhatnagar R, Laskawiec-Szkonter M, Piotrowska HEG. et al. Evaluating the efficacy of thoracoscopy and talc poudrage versus pleurodesis using talc slurry (TAPPS trial): protocol of an open-label randomised controlled trial. BMJ Open 2014; 4 (11) e007045
  • 61 ORiain SC, Donnell BO, Cuffe T, Harmon DC, Fraher JP, Shorten G. Thoracic paravertebral block using real-time ultrasound guidance. Anesth Analg 2010; 110 (01) 248-251
  • 62 Bashandy GMN, Abbas DN. Pectoral nerves I and II blocks in multimodal analgesia for breast cancer surgery: a randomized clinical trial. Reg Anesth Pain Med 2015; 40 (01) 68-74
  • 63 Blanco R, Parras T, McDonnell JG, Prats-Galino A. Serratus plane block: a novel ultrasound-guided thoracic wall nerve block. Anaesthesia 2013; 68 (11) 1107-1113
  • 64 Botsa E, Mylona S, Koutsogiannis I, Koundouraki A, Thanos L. CT image guided thermal ablation techniques for palliation of painful bone metastases. Ann Palliat Med 2014; 3 (02) 47-53
  • 65 Goetz MP, Callstrom MR, Charboneau JW. et al. Percutaneous image-guided radiofrequency ablation of painful metastases involving bone: a multicenter study. J Clin Oncol 2004; 22 (02) 300-306
  • 66 Gangi A, Sabharwal T, Irani FG, Buy X, Morales JP, Adam A. Standards of Practice Committee of the Society of Interventional Radiology. Quality assurance guidelines for percutaneous vertebroplasty. Cardiovasc Intervent Radiol 2006; 29 (02) 173-178
  • 67 Yang H-L, Sun Z-Y, Wu G-Z, Chen K-W, Gu Y, Qian Z-L. Do vertebroplasty and kyphoplasty have an antitumoral effect?. Med Hypotheses 2011; 76 (01) 145-146
  • 68 Kuerer HM, Rauch GM, Krishnamurthy S. et al. A clinical feasibility trial for identification of exceptional responders in whom breast cancer surgery can be eliminated following neoadjuvant systemic therapy. Ann Surg 2018; 267 (05) 946-951
  • 69 Heil J, Kümmel S, Schaefgen B. et al. Diagnosis of pathological complete response to neoadjuvant chemotherapy in breast cancer by minimal invasive biopsy techniques. Br J Cancer 2015; 113 (11) 1565-1570
  • 70 Giuliano AE, Hunt KK, Ballman KV. et al. Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial. JAMA 2011; 305 (06) 569-575
  • 71 Henke G, Knauer M, Ribi K. et al. Tailored axillary surgery with or without axillary lymph node dissection followed by radiotherapy in patients with clinically node-positive breast cancer (TAXIS): study protocol for a multicenter, randomized phase-III trial. Trials 2018; 19 (01) 667
  • 72 Carter S, Neuman H, Mamounas EP. et al. Debating the optimal approach to nodal management after pathologic complete response to neoadjuvant chemotherapy in patients with breast cancer. Am Soc Clin Oncol Educ Book 2019; 39: 42-48
  • 73 Lee J, Choi JE, Kim SJ. et al. Korean Breast Cancer Society. Comparative study between sentinel lymph node biopsy and axillary dissection in patients with one or two lymph node metastases. J Breast Cancer 2018; 21 (03) 306-314
  • 74 Verheuvel NC, Voogd AC, Tjan-Heijnen VCG, Roumen RMH. Potential impact of application of Z0011 derived criteria to omit axillary lymph node dissection in node positive breast cancer patients. Eur J Surg Oncol 2016; 42 (08) 1162-1168
  • 75 Haffty BG, McCall LM, Ballman KV, Buchholz TA, Hunt KK, Boughey JC. Impact of radiation on locoregional control in women with node-positive breast cancer treated with neoadjuvant chemotherapy and axillary lymph node dissection: results from ACOSOG Z1071 clinical trial. Int J Radiat Oncol Biol Phys 2019; 105 (01) 174-182
  • 76 Shin K, Caudle AS, Kuerer HM. et al. Radiologic mapping for targeted axillary dissection: needle biopsy to excision. AJR Am J Roentgenol 2016; 207 (06) 1372-1379