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DOI: 10.1055/s-0041-1733928
Reliability of Contralateral Suppression in Evoked Distortion Product Otoacoustic Emissions
Funding Conselho Nacional de Desenvolvimento Científico e Tecnológico (Grant/Award Number: 309144/2018) and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES – Grant/Award Number: 001).![](https://www.thieme-connect.de/media/10.1055-s-00025477/202202/lookinside/thumbnails/10-1055-s-0041-1733928_200331-1.jpg)
Abstract
Introduction Distortion product otoacoustic emissions (DPOAE) and their suppression may be considered useful in monitoring cochlear function and the efferent auditory pathway inhibitory effect. Nonetheless, the establishment of reliable parameters of response variations is of great importance.
Objectives To verify the replicability of test and retest in the research of the inhibitory effect of the efferent pathway using contralateral suppressing stimulus during DPOAE recording for clinical applicability.
Methods Cross-sectional study with 48 volunteers, aged 18 to 30 years, with normal audiometric thresholds. The procedures included were audiometric and immittance measures to overrule any conductive or sensorineural conditions and DPOAE recordings without and with contralateral suppression with a 60 dBHL white noise. Distortion product otoacoustic emissions amplitudes were analyzed and compared in both conditions with Wilcoxon test, and the Spearman correlation test was used to assess test-retest reliability.
Results The comparative analysis showed differences between amplitudes in test and retest conditions only in 1,500 Hz for DPOAE measures with all other tested frequencies showing no differences, and no difference was observed in all recorded frequencies in the test and retest comparison for DPOAE suppression. The degree of correlation between test and retest of DPOAE amplitude was good at 6,000 Hz and strong (r > 0.880) at the other frequencies. For DPOAE with suppression, all frequencies presented strong correlation between test and retest: 1,500 Hz (r = 0.880), 2,000 Hz (r = 0.882), 3,000 Hz (r = 0.940), and 6,000 Hz (r = 0.957).
Conclusions The study found good replicability in contralateral suppression of DPOAE with potential clinical applicability, and we recommend conducting the test from 2000Hz to higher frequencies for more reliable results.
Keywords
cochlear hair cells - auditory efferent pathway - reproducibility of results - hearing loss - young adult - noise effectsPublication History
Received: 07 October 2020
Accepted: 07 April 2021
Article published online:
30 August 2021
© 2021. Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Vallejo JC, Silva MN, Oliveira JAA. et al. Detecção precoce de ototoxicidade usando emissões otoacústicas produtivas de distorção. Rev Bras Otorrinolaringol 2001; 67 (06) 845-851
- 2 Ramos N, Aita ADC, Siqueira LP, Aita FS. O uso de emissões otoacústicas como ferramenta auxiliar no diagnóstico de efeitos da exposição ao ruído. Rev Bras Saúde Ocup 2011; 36 (124) 282-287
- 3 Kemp DT. Stimulated acoustic emissions from within the human auditory system. J Acoust Soc Am 1978; 64 (05) 1386-1391
- 4 Couto CM, Carvallo RMM. O efeito das orelhas externa e média nas emissões otoacústicas. Rev Bras Otorrinolaringol 2009; 75 (01) 15-23
- 5 Kalaiah MK, Lasrado A, Pinto N, Shastri U. Short Term Test-Retest Reliability of Contralateral Inhibition of Distortion Product Otoacoustic Emissions. J Audiol Otol 2018; 22 (04) 189-196
- 6 Guedes MC, Passos SN, Gomez MVSG, Bento RF. Estudo da reprodutibilidade das emissões otoacústicas em indivíduos normais. Rev Bras Otorrinolaringol 2002; 68 (01) 34-38
- 7 Marques FP, Costa EA. Exposição ao ruído ocupacional: alterações no exame de emissões otoacústicas. Rev Bras Otorrinolaringol 2006; 72 (03) 362-366
- 8 Leme VN. Emissões Otoacústicas: Efeito da estimulação acústica contralateral e bilateral na função do sistema auditivo eferente. Dissertação: Faculdade de Medicina da Universidade de São Paulo; 2009
- 9 Burguetti FAR, Carvallo RMM. Sistema auditivo eferente: efeito no processamento auditivo. Rev Bras Otorrinolaringol 2008; 74 (05) 737-745
- 10 Oliveira JRM, Fernandes JC, Costa Filho OA. Influência da idade na atividade do sistema eferente nas propriedades mecânicas da cóclea de ouvintes normais. Rev Bras Otorrinolaringol (Engl Ed) 2009; 75 (03) 340-344
- 11 Guinan Jr JJ. Olivocochlear efferents: anatomy, physiology, function, and the measurement of efferent effects in humans. Ear Hear 2006; 27 (06) 589-607
- 12 Kumar UA, Methi R, Avinash MC. Test/retest repeatability of effect contralateral acoustic stimulation on the magnitudes of distortion product ototacoustic emissions. Laryngoscope 2013; 123 (02) 463-471
- 13 Mor R, Azevedo MF. Emissões otoacústicas e sistema olivococlear medial: pacientes com zumbido sem perda auditiva. Pró-Fono Rev Atual Cient 2005; 17 (03) 283-292
- 14 Mishra SK, Abdala C. Stability of the medial olivocochlear reflex as measured by distortion product otoacoustic emissions. J Speech Lang Hear Res 2015; 58 (01) 122-134
- 15 Zhao F, Stephens D. Test-retest variability of distortion-product otoacoustic emissions in human ears with normal hearing. Scand Audiol 1999; 28 (03) 171-178
- 16 Roede J, Harris FP, Probst R, Xu L. Repeatability of distortion product otoacoustic emissions in normally hearing humans. Audiology 1993; 32 (05) 273-281
- 17 Franklin DJ, McCoy MJ, Martin GK, Lonsbury-Martin BL. Test/retest reliability of distortion-product and transiently evoked otoacoustic emissions. Ear Hear 1992; 13 (06) 417-429
- 18 Abdala C, Ma E, Sininger YS. Maturation of medial efferent system function in humans. J Acoust Soc Am 1999; 105 (04) 2392-2402
- 19 Wagner W, Heppelmann G, Vonthein R, Zenner HP. Test-retest repeatability of distortion product otoacoustic emissions. Ear Hear 2008; 29 (03) 378-391
- 20 Ng IH-Y, McPherson B. Test-Retest Reliability of Distortion Product Otoacoustic Emissions in the 1 to 7 kHz Range. Audiol Med 2005; 3 (02) 108-115