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Semin Respir Crit Care Med 2021; 42(03): 329-345
DOI: 10.1055/s-0041-1728756
Review Article

Selection Criteria for Lung Transplantation: Controversies and New Developments

Hanne Beeckmans
1   Division of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium
,
Saskia Bos
1   Division of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium
,
Robin Vos 
1   Division of Respiratory Diseases, University Hospitals Leuven, Leuven, Belgium
2   Department of Chronic Diseases, Metabolism and Ageing (CHROMETA), BREATHE, Leuven, Belgium
› Author Affiliations Funding R.V. is supported by a research fellowship as senior clinical research fellow of Research Foundation—Flanders (FWO).
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Abstract

Lung transplantation is an accepted therapeutic option for end-stage lung diseases. The imbalance between limited availability and vast need of donor organs necessitates careful selection of recipient candidates, ensuring the best possible utilization of the scarce resource of organs. Nonetheless, possible lung transplant candidates who could experience a meaningful improvement in survival and quality of life should not be excluded solely based on the complexity of their case. In this review, controversial issues or difficult limitations for lung transplantation, and new developments in recipient selection criteria, are discussed, which may help broaden recipient eligibility for lung transplantation without compromising long-term outcomes.

Keywords

lung transplantation - indication - contraindication - donor selection - recipient selection - selection criteria

Authors' Contributions

H.B. performed research/study, collected data, wrote the manuscript, S.B. revised the data and manuscript critically, R.V. conceived and supervised the study and critically revised the data and the manuscript.




Publication History

Article published online:
24 May 2021

© 2021. Thieme. All rights reserved.

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