Severe Consumptive Coagulopathy in an Extremely-Low-Birth-Weight Infant with Intra-Abdominal Umbilical Vein Varix: A Case Report

Abstract

Recent studies have shown favorable outcomes for intra-abdominal umbilical vein varices (IUVVs) in term neonates who have no other complications. Little is known, however, about the prognosis of IUVVs in preterm neonates. We encountered a case of IUVV in an extremely low-birth-weight infant who developed severe consumptive coagulopathy after birth. The patient's coagulation test normalized as the varix spontaneously obstructed. Although life-threatening hemorrhagic complications were avoided, a cerebellum hemorrhage was found in the brain magnetic resonance imaging at the term-equivalent age. In a literature survey, coagulopathy was reported in 4 out of 15 infants with IUVVs born before 34 weeks of gestation, including our present case. Preterm infants with IUVVs may develop coagulopathy because of the prematurity of their coagulation–fibrinolysis systems. Attention should be given to the coagulation status of preterm neonates with IUVVs.

Keywords

intra-abdominal umbilical vein varix - consumptive coagulopathy - extremely-low-birth-weight infants - intracranial hemorrhages

Informed Consent

Informed consent was obtained from the patient's parents for the publication of this case report and any accompanying images.

Disclosure

The authors declare that they have no known competing financial interests or personal relationships that could influence the work reported in this paper.

Publikationsverlauf

Eingereicht: 13. Januar 2021

Angenommen: 15. Februar 2021

Artikel online veröffentlicht:
27. Mai 2021

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