RSS-Feed abonnieren
DOI: 10.1055/s-0041-1726603
Multiple Myeloma Involving Left Hemicranium
Abstract
Multiple myeloma (MM) is a malignant neoplasm of bone marrow affecting plasma cells. It is commonly seen as multiple punched-out lesions in the skull bone as a characteristic feature. Its presentation as hemicranial involvement with intracranial extension is rare. A 46-year-old male presented with left side scalp swelling, prominent over parietal region. X-ray showed multiple punched out lesions involving left hemicranium. CT and MRI brain showed intracranial extension of lesion without brain parenchyma invasion. He was treated with biopsy of lesion followed by chemotherapy.
Publikationsverlauf
Artikel online veröffentlicht:
13. Januar 2022
© 2022. Neurological Surgeons’ Society of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Kyle RA, Rajkumar SV. Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma. Leukemia 2009; 23 (01) 3-9
- 2 Kuehl WM, Bergsagel PL. Molecular pathogenesis of multiple myeloma and its premalignant precursor. J Clin Invest 2012; 122 (10) 3456-3463
- 3 Muttaqin Z, Arita K, Uozumi T. et al. Vasospasm after traumatic subarachnoid haemorrhage: transcranial Doppler evaluation. Case report. Neurosurg Rev 1991; 14 (04) 321-325
- 4 Bitelman VM, Lopes JAD de O, Nogueira AB, Frassetto FP, Duarte-Neto AN. “Punched out” multiple myeloma lytic lesions in the skull. Autops Case Rep 2016; 6 (01) 7-9
- 5 Niesvizky R, Warrell Jr RP. Pathophysiology and management of bone disease in multiple myeloma. Cancer Invest 1997; 15 (01) 85-90
- 6 Angtuaco EJC, Fassas ABT, Walker R, Sethi R, Barlogie B. Multiple myeloma: clinical review and diagnostic imaging. Radiology 2004; 231 (01) 11-23
- 7 Roodman GD. Role of the bone marrow microenvironment in multiple myeloma. Journal of Bone and Mineral Research 2009; 17 (11) 1921-1925
- 8 Senapati SB, Mishra SS, Dhir MK, Das S, Tripathy K. A case of multiple myeloma presenting as scalp swelling with intracranial extension. J Neurosci Rural Pract 2013; 4 (04) 445-448
- 9 Kumar S, Jain AP, Waghmare S. Multiple cystic swelling: initial presentation of multiple myeloma. Indian J Med Paediatr Oncol 2010; 31 (01) 28-29