Endosc Int Open 2016; 04(03): E252-E254
DOI: 10.1055/s-0041-111500
Case report
© Georg Thieme Verlag KG Stuttgart · New York

A case of carcinoma in an adenoma of the duodenal minor papilla successfully treated with endoscopic mucosal resection

Toru Matsui
1   Division of Endoscopy, Shizuoka Cancer Center, Nagaizumi, Suntogun, Shizuoka, Japan
,
Hiroyuki Matsubayashi
1   Division of Endoscopy, Shizuoka Cancer Center, Nagaizumi, Suntogun, Shizuoka, Japan
,
Kinichi Hotta
1   Division of Endoscopy, Shizuoka Cancer Center, Nagaizumi, Suntogun, Shizuoka, Japan
,
Keiko Sasaki
2   Division of Pathology, Shizuoka Cancer Center, Nagaizumi, Suntogun, Shizuoka, Japan
,
Hiroaki Ito
3   Division of Diagnostic Radiology, Shizuoka Cancer Center, Nagaizumi, Suntogun, Shizuoka, Japan
,
Hiroyuki Ono
1   Division of Endoscopy, Shizuoka Cancer Center, Nagaizumi, Suntogun, Shizuoka, Japan
› Author Affiliations
Further Information

Publication History

submitted 08 August 2015

accepted after revision 14 December 2015

Publication Date:
10 February 2016 (online)

Background and study aims: Endoscopic papillectomy is currently used to treat noninvasive tumors of the papilla of Vater, but it is seldom reported for treatment of similar tumors of the minor papilla. This report describes the case of a 69-year-old female with a tumor located at the duodenal minor papilla. Findings of duodenoscopy, biopsy, and pancreatography indicated that her noninvasive tumor of the minor papilla was suitable for treatment with endoscopic resection. Glycerol-injected endoscopic mucosal resection (EMR) was performed, and the resected material histologically showed carcinoma in the adenoma, negative for neoplastic extension at the cut margin. No complications occurred during the treatment course, and no recurrence has been recognized for 80 months. Unlike the major papilla of Vater, the minor papilla can be lifted up by submucosal injection. Noninvasive epithelial tumors of the duodenal minor papilla without extension to the pancreatic duct can be successfully treated with EMR, as the technique is easy, it is minimally invasive, and it is curative.

 
  • References

  • 1 Yamao K, Ohhashi K, Furukawa T et al. Primary carcinoma of the duodenal minor papilla. Gastrointest Endosc 1998; 48: 634-636
  • 2 Fukuda A, Yazumi S, Sawada M et al. Adenomyoma of the minor duodenal papilla. Gastrointest Endosc 2005; 61: 475-479
  • 3 Wang HY, Chen MJ, Yang TL et al. Carcinoid tumor of the duodenum and accessory papilla associated with polycythemia vera. World J Gastroenterol 2005; 11: 3794-3796
  • 4 Chini P, Draganov PV. Diagnosis and management of ampullary adenoma: The expanding role of endoscopy. World J Gastrointest Endosc 2011; 3: 241-247
  • 5 Ito K, Fujita N, Noda Y. Endoscopic diagnosis and treatment of ampullary neoplasm (with video). Dig Endosc 2011; 23: 113-117
  • 6 Sugiyama M, Kimura W, Muto T et al. Endoscopic resection of adenoma of the minor papilla. Hepatogastroenterology 1999; 46: 189-192
  • 7 Trevino JM, Wilcox CM, Varadarajulu S. Endoscopic resection of minor papilla adenomas (with video). Gastrointest Endosc 2008; 68: 383-386
  • 8 Binmoeller KF, Boaventura S, Ramsperger K et al. Endoscopic snare excision of benign adenomas of the papilla of Vater. Gastrointest Endosc 1993; 39: 127-131
  • 9 Matsubayashi H, Watanabe H, Yamaguchi T et al. Differences in mucus and K-ras mutation in relation to phenotypes of tumors of the papilla of vater. Cancer 1999; 86: 596-607
  • 10 Suda K. Histopathology of the minor duodenal papilla. Dig Surg 2010; 27: 137-139