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DOI: 10.1055/s-0041-108571
Harnableitung und Rekonstruktion nach Zystektomie
Publication History
Publication Date:
15 December 2015 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00026982/201504/lookinside/thumbnails/014_10-1055-s-0041-108571-1.jpg)
Zusammenfassung
Kontinente Harnableitungen mit ausgeschalteten Darmschlingen sind derzeit bei Männern und Frauen das Verfahren der Wahl nach radikaler Zystektomie. Bei sorgfältig ausgewählten Patienten kann durch die Erschaffung einer Neoblase die Notwendigkeit eines äußeren Stomas verhindert und das Körperbild bewahrt werden, ohne die Tumorchirurgie zu kompromittieren. Der Patient muss ausführlich darüber in Kenntnis gesetzt werden, dass es eines hohen Maßes an Eigenengagement während des Rehabilitationsprozesses bedarf. Darüber hinaus sollte er ein gewisses Maß an Fingerfertigkeit besitzen, um im Fall der Fälle Selbstkatheterismus durchführen zu können.
Eine Tumorbeteiligung der Harnröhre verhindert den Einsatz einer orthotopen Neoblase. Ein kontinentes kutanes Reservoir bietet im Vergleich zum inkontinenten Ileumkonduit jedoch wesentliche Vorteile. Bei jenen Patienten, bei denen keine Art der kontinenten Ableitung infrage kommt, bleibt das Ileumkonduit weiterhin eine geeignete und zuverlässige Alternative.
Durch diese Fortschritte im Bereich der rekonstruktiven Chirurgie können Patienten die radikale Zystektomie in einem früheren Stadium des Blasentumors eher/leichter akzeptieren als erst im Rahmen der Second-Line-Therapie. Das kann das Outcome bei der Behandlung von Blasentumoren endgültig verbessern.
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Literatur
- 1 Estape R, Mendez LE, Angioli R et al. Urinary diversion in gynecologic oncology. Surg Clin North Am 2001; 81: 781-797
- 2 Petros JG, Augustinos P, Lopez MJ. Pelvic exenteration for carcinoma of the colon and rectum. Semin Surg Oncol 1999; 17: 206-212
- 3 Kaefer M, Tobin MS, Hendren WH et al. Continent urinary diversion: the Children's Hospital experience. J Urol 1997; 157: 1394-1399
- 4 Adams MC, Mitchell ME, Rink RC. Gastrocystoplasty: an alternative solution to the problem of urological reconstruction in the severely compromised patient. J Urol 1988; 140: 1152-1156
- 5 Kaveggia FF, Thompson JS, Schafer EC et al. Hyperammonemic encephalopathy in urinary diversion with urea-splitting urinary tract infection. Arch Intern Med 1990; 150: 2389-2392
- 6 McDougal WS, Koch MO. Accurate determination of renal function in patients with intestinal urinary diversions. J Urol 1986; 135: 1175-1178
- 7 Koch MO, McDougal WS, Flora MD. Urease and the acidosis of urinary intestinal diversion. J Urol 1991; 146: 458-462
- 8 Koch MO, McDougal WS, Thompson CO. Mechanisms of solute transport following urinary diversion through intestinal segments: an experimental study with rats. J Urol 1991; 146: 1390-1394
- 9 Klein EA, Montie JE, Montague DK et al. Jejunal conduit urinary diversion. J Urol 1986; 135: 244-246
- 10 Plawker MW, Rabinowitz SS, Etwaru DJ et al. Hypergastrinemia, dysuria-hematuria and metabolic alkalosis: complications associated with gastrocystoplasty. J Urol 1995; 154: 546-549
- 11 Nguyen DH, Bain MA, Salmonson KL et al. The syndrome of dysuria and hematuria in pediatric urinary reconstruction with stomach. J Urol 1993; 150: 707-709
- 12 Gosalbez Jr R, Woodard JR, Broecker BH et al. Metabolic complications of the use of stomach for urinary reconstruction. J Urol 1993; 150: 710-712
- 13 Filipsson S, Hultén L, Lindstedt G. Malabsorption of fat and vitamin B12 before and after intestinal resection for Crohnʼs disease. Scand J Gastroenterol 1978; 13: 529-536
- 14 Thompson WG, Wrathell E. The relation between ileal resection and vitamin B12 absorption. Can J Surg 1977; 20: 461-464
- 15 Koch MO, McDougal WS. Chlorpromazine: adjuvant therapy for the metabolic derangements created by urinary diversion through intestinal segments. J Urol 1985; 134: 165-169
- 16 Boyd SD, Schiff WM, Skinner DG et al. Prospective study of metabolic abnormalities in patient with continent Kock pouch urinary diversion. Urology 1989; 33: 85-88
- 17 Koch MO, Gurevitch E, Hill DE et al. Urinary solute transport by intestinal segments: a comparative study of ileum and colon in rats. J Urol 1990; 143: 1275-1279
- 18 Mills RD, Studer UE. Metabolic consequences of continent urinary diversion. J Urol 1999; 161: 1057-1066
- 19 Stampfer DS, McDougal WS, McGovern FJ. The use of in bowel urology. Metabolic and nutritional complications. Urol Clin North Am 1997; 24: 715-722
- 20 McDougal WS, Stampfer DS, Kirley S et al. Intestinal ammonium transport by ammonium and hydrogen exchange. J Am Coll Surg 1995; 181: 241-248
- 21 Bricker EM. Bladder substitution after pelvic evisceration. Surg Clin North Am 1950; 30: 1511-1522
- 22 Hautmann RE. Urinary diversion: ileal conduit to neobladder. J Urol 2003; 169: 834-842
- 23 Gschwend JE. Bladder substitution. Curr Opin Urol 2003; 13: 477-482
- 24 Madersbacher S, Schmidt J, Eberle JM et al. Long-term outcome of ileal conduit diversion. J Urol 2003; 169: 985-990
- 25 Turnbull Jr RB. Intestinal stomas. Surg Clin North Am 1958; 38: 1361-1372
- 26 Farnham SB, Cookson MS. Surgical complications of urinary diversion. World J Urol 2004; 22: 157-167
- 27 Kouba E, Sands M, Lentz A et al. Incidence and risk factors of stomal complications in patients undergoing cystectomy with ileal conduit urinary diversion for bladder cancer. J Urol 2007; 178: 950-954
- 28 Liu NW, Hackney JT, Gellhaus PT et al. Incidence and risk factors of parastomal hernia in patients undergoing radical cystectomy and ileal conduit diversion. J Urol 2014; 191: 1313-1318
- 29 Donahue TF, Bochner BH, Sfakianos JP et al. Risk factors for the development of parastomal hernia after radical cystectomy. J Urol 2014; 191: 1708-1713
- 30 Bloch WE, Bejany DE, Penalver MA et al. Complications of the Miami pouch. J Urol 1992; 147: 1017-1019
- 31 Kock NG, Nilson AE, Nilsson LO et al. Urinary diversion via a continent ileal reservoir: clinical results in 12 patients. J Urol 1982; 128: 469-475
- 32 Rowland RG, Mitchell ME, Bihrle R et al. Indiana continent urinary reservoir. J Urol 1987; 137: 1136-1139
- 33 Holmes DG, Thrasher JB, Park GY et al. Long-term complications related to the modified Indiana pouch. Urology 2002; 60: 603-606
- 34 Bochner BH, McCreath WA, Aubey JJ et al. Use of an ureteroileocecal appendicostomy urinary reservoir in patients with recurrent pelvic malignancies treated with radiation. Gynecol Oncol 2004; 94: 140-146
- 35 Mirhashemi R, Lamrbou N, Hus N et al. The gastrointestinal complications of the Miami Pouch: a review of 77 cases. Gynecol Oncol 2004; 92: 220-224
- 36 Angioli R, Estape R, Cantuaria G et al. Urinary complications of Miami pouch: trend of conservative management. Am J Obstet Gynecol 1998; 179: 343-348
- 37 Bochner BH, Karanikolas N, Barakat RR et al. Ureteroileocecal appendicostomy based urinary reservoir in irradiated and nonirradiated patients. J Urol 2009; 182: 2376-2380
- 38 Stenzl A, Höltl L. Orthotopic bladder reconstruction in women – what we have learned over the last decade. Crit Rev Oncol Hematol 2003; 47: 147-154
- 39 Steven K, Poulsen AL. The orthotopic Kock ileal neobladder: functional results, urodynamic features, complications and survival in 166 men. J Urol 2000; 164: 288-295
- 40 Sullivan JW, Grabstald H, Whitmore Jr WF. Complications of ureteroileal conduit with radical cystectomy: review of 336 cases. J Urol 1980; 124: 797-801
- 41 Middleton Jr AW, Hendren WH. Ileal conduits in children at the Massachusetts General Hospital from 1955 to 1970. J Urol 1976; 115: 591-595
- 42 Richie JP, Skinner DG, Waisman J. The effect of reflux on the development of pyelonephritis in urinary diversion: an experimental study. J Surg Res 1974; 16: 256-261
- 43 Studer UE, Danuser H, Thalmann GN et al. Antireflux nipples or afferent tubular segments in 70 patients with ileal low pressure bladder substitutes: long-term results of a prospective randomized trial. J Urol 1996; 156: 1913-1917
- 44 Boxer RJ, Fritzsche P, Skinner DG et al. Replacement of the ureter by small intestine: clinical application and results of the ileal ureter in 89 patients. J Urol 1979; 121: 728-731
- 45 Pantuck AJ, Han KR, Perrotti M et al. Ureteroenteric anastomosis in continent urinary diversion: long-term results and complications of direct versus nonrefluxing techniques. J Urol 2000; 163: 450-455
- 46 Shaaban AA, Abdel-Latif M, Mosbah A et al. A randomized study comparing an antireflux system with a direct ureteric anastomosis in patients with orthotopic ileal neobladders. BJU Int 2006; 97: 1057-1062
- 47 Madersbacher S, Möhrle K, Burkhard F et al. Long-term voiding pattern of patients with ileal orthotopic bladder substitutes. J Urol 2002; 167: 2052-2057
- 48 Simon J, Bartsch Jr G, Küfer R et al. Neobladder emptying failure in males: incidence, etiology and therapeutic options. J Urol 2006; 176: 1468-1472
- 49 Ali-el-Dein B, el-Sobky E, Hohenfellner M et al. Orthotopic bladder substitution in women: functional evaluation. J Urol 1999; 161: 1875-1880
- 50 Stenzl A, Jarolim L, Coloby P et al. Urethra-sparing cystectomy and orthotopic urinary diversion in women with malignant pelvic tumors. Cancer 2001; 92: 1864-1871
- 51 Hautmann RE, de Petriconi R, Kleinschmidt K et al. Orthotopic ileal neobladder in females: impact of the urethral resection line on functional results. Int Urogynecol J Pelvic Floor Dysfunct 2000; 11: 224-229
- 52 Arai Y, Okubo K, Konami T et al. Voiding function of orthotopic ileal neobladder in women. Urology 1999; 54: 44-49
- 53 Stein JP, Penson DF, Lee C et al. Long-term oncological outcomes in women undergoing radical cystectomy and orthotopic diversion for bladder cancer. J Urol 2009; 181: 2052-2058
- 54 Steers WD. Voiding dysfunction in the orthotopic neobladder. World J Urol 2000; 18: 330-337
- 55 Hassan JM, Cookson MS, Smith Jr JA et al. Urethral recurrence in patients following orthotopic urinary diversion. J Urol 2004; 172: 1338-1341
- 56 Stein JP, Clark P, Miranda G et al. Urethral tumor recurrence following cystectomy and urinary diversion: clinical and pathological characteristics in 768 male patients. J Urol 2005; 173: 1163-1168
- 57 Freeman JA, Tarter TA, Esrig D et al. Urethral recurrence in patients with orthotopic ileal neobladders. J Urol 1996; 156: 1615-1619
- 58 Ali-el-Dein B, Abdel-Latif M, Ashamallah A et al. Local urethral recurrence after radical cystectomy and orthotopic bladder substitution in women: a prospective study. J Urol 2004; 171: 275-278
- 59 Akkad T, Gozzi C, Deibl M et al. Tumor recurrence in the remnant urothelium of females undergoing radical cystectomy for transitional cell carcinoma of the bladder: long-term results from a single center. J Urol 2006; 175: 1268-1271
- 60 Bochner BH, Montie JE, Lee CT. Follow-up strategies and management of recurrence in urologic oncology bladder cancer: invasive bladder cancer. Urol Clin North Am 2003; 30: 777-789
- 61 Knapik JA, Murphy WM. Urethral wash cytopathology for monitoring patients after cystoprostatectomy with urinary diversion. Cancer 2003; 99: 352-356
- 62 Lin DW, Herr HW, Dalbagni G. Value of urethral wash cytology in the retained male urethra after radical cystoprostatectomy. J Urol 2003; 169: 961-963
- 63 Taylor JM, Spiess PE, Kassouf W et al. Management of urethral recurrence after orthotopic urinary diversion. BJU Int 2010; 106: 56-61
- 64 Clark PE, Stein JP, Groshen SG et al. The management of urethral transitional cell carcinoma after radical cystectomy for invasive bladder cancer. J Urol 2004; 172: 1342-1347
- 65 Dutta SC, Chang SC, Coffey CS et al. Health related quality of life assessment after radical cystectomy: comparison of ileal conduit with continent orthotopic neobladder. J Urol 2002; 168: 164-167
- 66 Hobisch A, Tosun K, Kinzl J et al. Quality of life after cystectomy and orthotopic neobladder versus ileal conduit urinary diversion. World J Urol 2000; 18: 338-344
- 67 Smith JA. The quality of life in men after radical cystectomy with a continent cutaneous diversion or orthotopic bladder substitution: is there a difference?. J Urol 2003; 170: 331
- 68 Månsson A, Davidsson T, Hunt S et al. The quality of life in men after radical cystectomy with a continent cutaneous diversion or orthotopic bladder substitution: is there a difference?. BJU Int 2002; 90: 386-390
- 69 Henningsohn L, Steven K, Kallestrup EB et al. Distressful symptoms and well-being after radical cystectomy and orthotopic bladder substitution compared with a matched control population. J Urol 2002; 168: 168-174
- 70 Porter MP, Penson DF. Health related quality of life after radical cystectomy and urinary diversion for bladder cancer: a systematic review and critical analysis of the literature. J Urol 2005; 173: 1318-1322
- 71 Smith AB, Raynor M, Amling CL et al. Multi-institutional analysis of robotic radical cystectomy for bladder cancer: perioperative outcomes and complications in 227 patients. J Laparoendosc Adv Surg Tech A 2012; 22: 17-21
- 72 Collins JW, Tyritzis S, Nyberg T et al. Robot-assisted radical cystectomy: description of an evolved approach to radical cystectomy. Eur Urol 2013; 64: 654-663
- 73 Goh AC, Gill IS, Lee DJ et al. Robotic intracorporeal orthotopic ileal neobladder: replicating open surgical principles. Eur Urol 2012; 62: 891-901
- 74 Tyritzis SI, Hosseini A, Collins J et al. Oncologic, functional, and complications outcomes of robot-assisted radical cystectomy with totally intracorporeal neobladder diversion. Eur Urol 2013; 64: 734-741
- 75 Link RE, Lerner SP. Rebuilding the lower urinary tract after cystectomy: a roadmap for patient selection and counseling. Semin Urol Oncol 2001; 19: 24-36
- 76 Austin PF, DeLeary G, Homsy YL et al. Long-term metabolic advantages of a gastrointestinal composite urinary reservoir. J Urol 1997; 158: 1704-1707
- 77 Lockhart JL, Davies R, Cox C et al. The gastroileoileal pouch: an alternative continent urinary reservoir for patients with short bowel, acidosis and/or extensive pelvic radiation. J Urol 1993; 150: 46-50
- 78 Ravi R, Dewan AK, Pandey KK. Transverse colon conduit urinary diversion in patients treated with very high dose pelvic irradiation. Br J Urol 1994; 73: 51-54
- 79 Kato H, Igawa Y, Komiyama I et al. Continent urinary reservoir formation with transverse colon for patients with pelvic irradiation. Int J Urol 2002; 9: 200-203
- 80 Yossepowitch O, Dalbagni G, Golijanin D et al. Orthotopic urinary diversion after cystectomy for bladder cancer: implications for cancer control and patterns of disease recurrence. J Urol 2003; 169: 177-181
- 81 Huguet J, Palou J, Serrallach M et al. Management of urethral recurrence in patients with Studer ileal neobladder. Eur Urol 2003; 43: 495-498
- 82 Varol C, Thalmann GN, Burkhard FC et al. Treatment of urethral recurrence following radical cystectomy and ileal bladder substitution. J Urol 2004; 172: 937-942
- 83 Nieder AM, Sved PD, Gomez P et al. Urethral recurrence after cystoprostatectomy: implications for urinary diversion and monitoring. Urology 2004; 64: 950-954
- 84 Yoshida K, Nishiyama H, Kinoshita H et al. Surgical treatment for urethral recurrence after ileal neobladder reconstruction in patients with bladder cancer. BJU Int 2006; 98: 1008-1011
- 85 Freeman JA, Esrig D, Stein JP et al. Management of the patient with bladder cancer. Urethral recurrence. Urol Clin North Am 1994; 21: 645-651
- 86 Stenzl A, Bartsch G, Rogatsch H. The remnant urothelium after reconstructive bladder surgery. Eur Urol 2002; 41: 124-131
- 87 Levinson AK, Johnson DE, Wishnow KI. Indications for urethrectomy in an era of continent urinary diversion. J Urol 1990; 144: 73-75
- 88 Tobisu K, Tanaka Y, Mizutani T et al. Transitional cell carcinoma of the urethra in men following cystectomy for bladder cancer: multivariate analysis for risk factors. J Urol 1991; 146: 1551-1553
- 89 Schellhammer PF, Whitmore Jr WF. Transitional cell carcinoma of the urethra in men having cystectomy for bladder cancer. J Urol 1976; 115: 56-60
- 90 Herr HW, Donat SM, Bajorin DF. Post-chemotherapy surgery in patients with unresectable or regionally metastatic bladder cancer. J Urol 2001; 165: 811-814
- 91 Donat SM, Wei DC, McGuire MS et al. The efficacy of transurethral biopsy for predicting the long-term clinical impact of prostatic invasive bladder cancer. J Urol 2001; 165: 1580-1584
- 92 Lebret T, Hervé JM, Barré P et al. Urethral recurrence of transitional cell carcinoma of the bladder. Predictive value of preoperative latero-montanal biopsies and urethral frozen sections during prostatocystectomy. Eur Urol 1998; 33: 170-174
- 93 Donat SM, Genega EM, Herr HW et al. Mechanisms of prostatic stromal invasion in patients with bladder cancer: clinical significance. J Urol 2001; 165: 1117-1120
- 94 Stein JP, Esrig D, Freeman JA et al. Prospective pathologic analysis of female cystectomy specimens: risk factors for orthotopic diversion in women. Urology 1998; 51: 951-955
- 95 Stenzl A, Colleselli K, Poisel S et al. Anterior exenteration with subsequent ureteroileal urethrostomy in females. Anatomy, risk of urethral recurrence, surgical technique, and results. Eur Urol 1998; 33 (Suppl. 04) 18-20
- 96 Maralani S, Wood Jr DP, Grignon D et al. Incidence of urethral involvement in female bladder cancer: an anatomic pathologic study. Urology 1997; 50: 537-541
- 97 Kassouf W, Spiess PE, Brown GA et al. Prostatic urethral biopsy has limited usefulness in counseling patients regarding final urethral margin status during orthotopic neobladder reconstruction. J Urol 2008; 180: 164-167
- 98 Van Poppel H, Sorgeloose T. Radical cystectomy with or without urethrectomy?. Crit Rev Oncol Hematol 2003; 47: 141-145
- 99 Studer UE, Burkhard FC, Schumacher M et al. Twenty years experience with an ileal orthotopic low pressure bladder substitute – lessons to be learned. J Urol 2006; 176: 161-166
- 100 Hardeman SW, Soloway MS. Urethral recurrence following radical cystectomy. J Urol 1990; 144: 666-669
- 101 Hautmann RE, de Petriconi R, Gottfried HW et al. The ileal neobladder: complications and functional results in 363 patients after 11 years of followup. J Urol 1999; 161: 422-427
- 102 Hautmann RE, Simon J. Ileal neobladder and local recurrence of bladder cancer: patterns of failure and impact on function in men. J Urol 1999; 162: 1963-1966
- 103 Srinivas S, Mahalati K, Freiha FS. Methotrexate tolerance in patients with ileal conduits and continent diversions. Cancer 1998; 82: 1134-1136
- 104 Bulbul MA, Wazzan W, Farhat W et al. Feasibility of radiation and chemotherapy following cystectomy and orthotopic neobladder for invasive bladder cancer. Can J Urol 1998; 5: 469-471
- 105 Millikan R, Dinney C, Swanson D et al. Integrated therapy for locally advanced bladder cancer: final report of a randomized trial of cystectomy plus adjuvant M-VAC versus cystectomy with both preoperative and postoperative M-VAC. J Clin Oncol 2001; 19: 4005-4013
- 106 Smith Jr JA, Whitmore Jr WF. Salvage cystectomy for bladder cancer after failure of definitive irradiation. J Urol 1981; 125: 643-645
- 107 Swanson DA, von Eschenbach AC, Bracken RB et al. Salvage cystectomy for bladder carcinoma. Cancer 1981; 47: 2275-2279
- 108 Ahlering TE, Kanellos A, Boyd SD et al. A comparative study of perioperative complications with Kock pouch urinary diversion in highly irradiated versus nonirradiated patients. J Urol 1988; 139: 1202-1204
- 109 Bochner BH, Figueroa AJ, Skinner EC et al. Salvage radical cystoprostatectomy and orthotopic urinary diversion following radiation failure. J Urol 1998; 160: 29-33
- 110 Chang SS, Alberts GL, Smith Jr JA et al. Ileal conduit urinary diversion in patients with previous history of abdominal/pelvic irradiation. World J Urol 2004; 22: 272-276
- 111 Gheiler EL, Wood Jr DP, Montie JE et al. Orthotopic urinary diversion is a viable option in patients undergoing salvage cystoprostatectomy for recurrent prostate cancer after definitive radiation therapy. Urology 1997; 50: 580-584
- 112 van Savage JG, Slaughenhoupt BL. Approach to urinary diversion in the surgical patient. J Surg Oncol 2000; 73: 33-38
- 113 Sogni F, Brausi M, Frea B et al. Morbidity and quality of life in elderly patients receiving ileal conduit or orthotopic neobladder after radical cystectomy for invasive bladder cancer. Urology 2008; 71: 919-923
- 114 Clark PE, Stein JP, Groshen SG et al. Radical cystectomy in the elderly: comparison of clinical outcomes between younger and older patients. Cancer 2005; 104: 36-43
- 115 Lee CT, Dunn RL, Chen BT et al. Impact of body mass index on radical cystectomy. J Urol 2004; 172: 1281-1285
- 116 Reyes MA, Nieder AM, Kava BR et al. Does body mass index affect outcome after reconstruction of orthotopic neobladder?. Urology 2007; 69: 475-478
- 117 Killeen KP, Libertino JA. Management of bowel and urinary tract complications after urinary diversion. Urol Clin North Am 1988; 15: 183-194
- 118 Perimenis P, Burkhard FC, Kessler TM et al. Ileal orthotopic bladder substitute combined with an afferent tubular segment: long-term upper urinary tract changes and voiding pattern. Eur Urol 2004; 46: 604-609
- 119 Morales P, Golimbu M. Colonic urinary diversion: 10 years of experience. J Urol 1975; 113: 302-307
- 120 Jahnson S, Pedersen J. Cystectomy and urinary diversion during twenty years--complications and metabolic implications. Eur Urol 1993; 24: 343-349
- 121 Parekh DJ, Gilbert WB, Koch MO et al. Continent urinary reconstruction versus ileal conduit: a contemporary single-institution comparison of perioperative morbidity and mortality. Urology 2000; 55: 852-855
- 122 Webster C, Bukkapatnam R, Seigne JD et al. Continent colonic urinary reservoir (Florida pouch): long-term surgical complications (greater than 11 years). J Urol 2003; 169: 174-176
- 123 Sumfest JM, Burns MW, Mitchell ME. The Mitrofanoff principle in urinary reconstruction. J Urol 1993; 150: 1875-1877
- 124 Bihrle R. The Indiana pouch continent urinary reservoir. Urol Clin North Am 1997; 24: 773-779
- 125 Zabell JR, Adejoro O, Konety BR et al. Risk of end stage kidney disease after radical cystectomy according to urinary diversion type. J Urol 2015; 193: 1283-1287
- 126 Eisenberg MS, Thompson RH, Frank I et al. Long-term renal function outcomes after radical cystectomy. J Urol 2014; 191: 619-625
- 127 Gershman B, Eisenberg MS, Thompson RH et al. Comparative impact of continent and incontinent urinary diversion on long-term renal function after radical cystectomy in patients with preoperative chronic kidney disease 2 and chronic kidney disease 3a. Int J Urol 2015; 22: 651-656
- 128 Wullt B, Holst E, Steven K et al. Microbial flora in ileal and colonic neobladders. Eur Urol 2004; 45: 233-239
- 129 Wood Jr DP, Bianco Jr FJ, Pontes JE et al. Incidence and significance of positive urine cultures in patients with an orthotopic neobladder. J Urol 2003; 169: 2196-2199
- 130 Holmes DG, Park GY, Thrasher JB et al. Incidence of cholelithiasis in 125 continent urinary diversions. J Urol 2001; 165: 1897-1899
- 131 Steven K, Poulsen AL. The orthotopic Kock ileal neobladder: functional results, urodynamic features, complications and survival in 166 men. J Urol 2000; 164: 288-295
- 132 Fujisawa M, Gotoh A, Nakamura I et al. Long-term assessment of serum vitamin B(12) concentrations in patients with various types of orthotopic intestinal neobladder. Urology 2000; 56: 236-240
- 133 Ganesan T, Khadra MH, Wallis J et al. Vitamin B12 malabsorption following bladder reconstruction or diversion with bowel segments. ANZ J Surg 2002; 72: 479-482
- 134 North AC, Lakshmanan Y. Malignancy associated with the use of intestinal segments in the urinary tract. Urol Oncol 2007; 25: 165-167
- 135 Aragona F, De Caro R, Parenti A et al. Structural and ultrastructural changes in ileal neobladder mucosa: a 7-year follow-up. Br J Urol 1998; 81: 55-61
- 136 Pickard R. Tumour formation within intestinal segments transposed to the urinary tract. World J Urol 2004; 22: 227-234
- 137 Azimuddin K, Khubchandani IT, Stasik JJ et al. Neoplasia after ureterosigmoidostomy. Dis Colon Rectum 1999; 42: 1632-1638
- 138 Fichtner J. Follow-up after urinary diversion. Urol Int 1999; 63: 40-45
- 139 Austen M, Kälble T. Secondary malignancies in different forms of urinary diversion using isolated gut. J Urol 2004; 172: 831-838
- 140 Ali-El-Dein B, El-Tabey N, Abdel-Latif M et al. Late uro-ileal cancer after incorporation of ileum into the urinary tract. J Urol 2002; 167: 84-88
- 141 Desgrandchamps F, Cariou G, Barthelemy Y et al. Spontaneous rupture of orthotopic detubularized ileal bladder replacement: report of 5 cases. J Urol 1997; 158: 798-800