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Am J Perinatol 2022; 39(10): 1055-1064
DOI: 10.1055/s-0040-1721694
Review Article

Maternal Cardiovascular Function Following a Pregnancy Complicated by Preeclampsia

Logan C. Barr
1   Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada
,
Kiera Liblik
2   Cardiovascular Imaging Network at Queen's, Department of Medicine, Queen's University, Kingston, Ontario, Canada
,
Amer M. Johri
2   Cardiovascular Imaging Network at Queen's, Department of Medicine, Queen's University, Kingston, Ontario, Canada
,
Graeme N. Smith 
1   Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada
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Abstract

Preeclampsia is a hypertensive pregnancy complication with an unknown etiology and high maternal burden worldwide. Burgeoning research has linked preeclampsia to adverse maternal health outcomes remote from pregnancy; however, the intermediary mechanisms responsible for this association have not been sufficiently established. In the present narrative review, we summarize leading evidence of structural and functional cardiovascular changes associated with prior preeclampsia, and how these changes may be linked to future maternal disease.

Key Points

  • Prior preeclampsia is associated with subclinical structural and functional vascular changes remote from pregnancy.

  • Maternal cardiac adaptations to preeclampsia may have long-term implications on cardiovascular health.

  • Clinicians have an opportunity to minimize maternal disease risk following preeclampsia.

Keywords

preeclampsia - postpartum period - arteries - heart - cardiovascular diseases


Publication History

Received: 11 July 2020

Accepted: 04 November 2020

Article published online:
15 December 2020

© 2020. Thieme. All rights reserved.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 

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