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Synthesis 2022; 54(08): 1951-1963
DOI: 10.1055/s-0040-1719893
DOI: 10.1055/s-0040-1719893
short review
Current Advances in Meerwein-type Radical Alkene Functionalizations
The authors are grateful for the support of their research work by the Deutsche Forschungsgemeinschaft (DFG, HE 5413/9-4).
Abstract
Alkene functionalizations via Meerwein arylations are becoming increasingly attractive, especially since a variety of mild and sustainable methods for aryl radical generation are available today. This entails a broad spectrum of substrates and radical scavengers, as well as convenient synthetic routes to relevant precursors for further transformations. The present review focuses on recent advances in Meerwein-type alkene functionalizations and gives insights into the key mechanistic details of the respective reactions.
1 Introduction
2 Hydroarylation and Carboarylation
3 Carboamination, Carbooxygenation, and Carbothiolation
4 Carbohalogenation
5 Conclusion and Outlook
Key words
Meerwein arylation - radical chemistry - photocatalysis - olefins - radical-polar crossoverPublication History
Received: 08 November 2021
Accepted after revision: 08 December 2021
Article published online:
02 March 2022
© 2022. Thieme. All rights reserved
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