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CC BY-NC-ND 4.0 · J Neurol Surg Rep 2020; 81(04): e66-e70
DOI: 10.1055/s-0040-1718408
Case Report

Radiation-Induced Malignant Peripheral Nerve Sheath Tumor of the Vagus Nerve Following Radiation Treatment of Cervical Paraganglioma

Gregory P. Lekovic
1   Division of Neurosurgery, House Institute, Los Angeles, California, United States
,
Gautam U. Mehta 
1   Division of Neurosurgery, House Institute, Los Angeles, California, United States
,
Anne K. Maxwell
2   Division of Neurotology, House Institute, Los Angeles, California, United States
,
Kevin A. Peng
2   Division of Neurotology, House Institute, Los Angeles, California, United States
,
Derald E. Brackmann
2   Division of Neurotology, House Institute, Los Angeles, California, United States
› Author Affiliations Funding None.
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Abstract

Radiation-induced sarcoma is a known but rare complication of radiation treatment for skull base paraganglioma. We present the cases of a female patient with multiple paraganglioma syndrome treated with external beam radiation treatment who presented 4 years later with a malignant peripheral nerve sheath tumor of the vagus nerve.

Keywords

paraganglioma - radiation - vagus nerve - malignant peripheral nerve sheath tumor - radiation-induced sarcoma - glomus vagale

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the Declaration of Helsinki 1964 and its later amendments or comparable ethical standards.


Patient Consent

The patient's next of kin has given consent for submission of this case report.




Publication History

Received: 16 March 2020

Accepted: 02 September 2020

Article published online:
31 December 2020

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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