Biodegradable Pancreatic and Biliary Stents—Still Searching For Disappearing Wonder?

Abstract

Biodegradable stents hold considerable promise in the treatment of benign biliary or pancreatic diseases with the major advantage being avoidance of repeated interventions for stent removal or stent exchange. They have been confirmed to have good biocompatibility and current evidence shows acceptable rates of clinical efficacy and safety. In the current news and views, we discuss an interesting study that has evaluated a new type of biodegradable biliary and pancreatic stent (the Archimedes stent) in benign biliary and pancreatic diseases.

Keywords

pancreatitis - stent - stricture

Publikationsverlauf

Artikel online veröffentlicht:
22. Juni 2020

• References

• 1 Bhasin DK, Rana SS. Biodegradable pancreatic stents: are they a disappearing wonder?. Gastrointest Endosc 2008; 67 (07) 1113-1116
• 2 Siiki A, Sand J, Laukkarinen J. A systematic review of biodegradable biliary stents: promising biocompatibility without stent removal. Eur J Gastroenterol Hepatol 2018; 30 (08) 813-818
• 3 Siiki A, Vaalavuo Y, Antila A. et al. Biodegradable biliary stents preferable to plastic stent therapy in post-cholecystectomy bile leak and avoid second endoscopy. Scand J Gastroenterol 2018; 53 (10-11) 1376-1380
• 4 Wang Z, Li N, Li R. et al. Biodegradable intestinal stents: a review. Prog Nat Sci Mater Int 2014; 24: 423-432
• 5 Ginsberg G, Cope C, Shah J. et al. In vivo evaluation of a new bioabsorbable self-expanding biliary stent. Gastrointest Endosc 2003; 58 (05) 777-784
• 6 Laukkarinen J, Lämsä T, Nordback I, Mikkonen J, Sand J. A novel biodegradable pancreatic stent for human pancreatic applications: a preclinical safety study in a large animal model. Gastrointest Endosc 2008; 67 (07) 1106-1112
• 7 Lorenzo-Zúñiga V, Moreno-de-Vega V, Marín I, Boix J. Biodegradable stents in gastrointestinal endoscopy. World J Gastroenterol 2014; 20 (09) 2212-2217
• 8 Petrtýl J, Brůha R, Horák L, Zádorová Z, Dosedel J, Laasch HU. Management of benign intrahepatic bile duct strictures: initial experience with polydioxanone biodegradable stents. Endoscopy 2010; 42 (Suppl. 02) E89-E90
• 9 Mauri G, Michelozzi C, Melchiorre F. et al. Biodegradable biliary stent implantation in the treatment of benign bilioplastic-refractory biliary strictures: preliminary experience. Eur Radiol 2013; 23 (12) 3304-3310
• 10 Mauri G, Michelozzi C, Melchiorre F. et al. Benign biliary strictures refractory to standard bilioplasty treated using polydoxanone biodegradable biliary stents: retrospective multicentric data analysis on 107 patients. Eur Radiol 2016; 26 (11) 4057-4063
• 11 Siiki A, Rinta-Kiikka I, Sand J, Laukkarinen J. Biodegradable biliary stent in the endoscopic treatment of cystic duct leak after cholecystectomy: the first case report and review of literature. J Laparoendosc Adv Surg Tech A 2015; 25 (05) 419-422
• 12 Siiki A, Rinta-Kiikka I, Sand J, Laukkarinen J. A pilot study of endoscopically inserted biodegradable biliary stents in the treatment of benign biliary strictures and cystic duct leaks. Gastrointest Endosc 2018; 87 (04) 1132-1137
• 13 Cahen DL, van der Merwe SW, Laleman W, Poley JW, Bruno MJ. A biodegradable non-covered self-expandable stent to treat pancreatic duct strictures in chronic pancreatitis: a proof of principle. Gastrointest Endosc 2018; 87 (02) 486-491
• 14 Anderloni A, Fugazza A, Maroni L. et al. New biliary and pancreatic biodegradable stent placement: a single-center, prospective, pilot study (with video). Gastrointest Endosc 2020; S0016-5107(20)30225-X (e-pub ahead of print) DOI: 10.1016/j.gie.2020.02.049.
• 15 G Almeida G. Donato P. Biodegradable versus multiple plastic stent implantation in benign biliary strictures: a systematic review and meta-analysis. Eur J Radiol 2020; 125: 108899