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CC BY-NC-ND 4.0 · Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery 2020; 39(03): 235-238
DOI: 10.1055/s-0040-1713093
Case Report | Relato de Caso

A Rare Case of Medulloblastoma with Supratentorial Metastasis Two Years after Treatment

Um caso raro de meduloblastoma com metástase supratentorial dois anos após o tratamento
Zoheir Reihanian 
1   Department of Neurosurgery, Guilan University of Medical Sciences, Rasht, Iran
,
Hamid Behzadnia 
1   Department of Neurosurgery, Guilan University of Medical Sciences, Rasht, Iran
,
Ahmad Kheiri Namin 
1   Department of Neurosurgery, Guilan University of Medical Sciences, Rasht, Iran
,
Nooshin Zaresharifi 
2   Department of Pathology, Tehran University of Medical Sciences, Tehran, Iran
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Abstract

One of the most invasive malignant tumors of the cerebellum is medulloblastoma, which is also the most common malignant tumor of the brain in children. Patients with a recurrent disease following initial treatment have the most unfavorable prognosis. The most common metastasis locations are the spine, the posterior fossa, the bones, and the supratentorium. Late medulloblastoma metastasis in the supratentorial intraventricular region is uncommon. We report here a case with supratentorial seeding.

Resumo

Um dos tumores malignos mais invasivos do cerebelo é o meduloblastoma, que também é o tumor maligno mais comum do cérebro em crianças. Pacientes com a doença recorrente após o tratamento inicial têm o prognóstico mais desfavorável. Os locais mais comuns de metástase são a coluna vertebral, a fossa posterior, os ossos, e o supratentório. Metástase tardia de meduloblastoma na região intraventricular supratentorial é incomum. Relatamos aqui um caso com semeadura supratentorial.

Keywords

medulloblastoma - metastasis - supratentorial - recurrence

Palavras-chave

meduloblastoma - metástase - supratentorial - reincidência


Publication History

Received: 18 March 2020

Accepted: 22 April 2020

Article published online:
07 August 2020

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Rio de Janeiro, Brazil

 

  • References

  • 1 Thomas A, Noël G. Medulloblastoma: optimizing care with a multidisciplinary approach. J Multidiscip Healthc 2019; 12: 335-347
    CrossrefPubMedGoogle Scholar
  • 2 Packer RJ, Gajjar A, Vezina G. , et al. Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma. J Clin Oncol 2006; 24 (25) 4202-4208
    CrossrefPubMedGoogle Scholar
  • 3 Sun L-M, Yeh S-A, Wang C-J. , et al. Postoperative radiation therapy for medulloblastoma--high recurrence rate in the subfrontal region. J Neurooncol 2002; 58 (01) 77-85
    CrossrefPubMedGoogle Scholar
  • 4 Roka YB, Bista P, Sharma GR, Adhikari D, Kumar P. Frontal recurrence of medulloblastoma five years after excision and craniospinal irradiation. Indian J Pathol Microbiol 2009; 52 (03) 383-385
    CrossrefPubMedGoogle Scholar
  • 5 Abode-Iyamah KO, Winslow N, Flouty O, Kirby P. Isolated Supratentorial Intraventricular Recurrence of Medulloblastoma. J Korean Neurosurg Soc 2015; 58 (06) 557-559
    CrossrefPubMedGoogle Scholar
  • 6 Sarkar C, Pramanik P, Karak AK. , et al. Are childhood and adult medulloblastomas different? A comparative study of clinicopathological features, proliferation index and apoptotic index. J Neurooncol 2002; 59 (01) 49-61
    CrossrefPubMedGoogle Scholar
  • 7 Massimino M, Casanova M, Polastri D. , et al. Relapse in medulloblastoma: what can be done after abandoning high-dose chemotherapy? A mono-institutional experience. Childs Nerv Syst 2013; 29 (07) 1107-1112
    CrossrefPubMedGoogle Scholar
  • 8 Miralbell R, Bleher A, Huguenin P. , et al. Pediatric medulloblastoma: radiation treatment technique and patterns of failure. Int J Radiat Oncol Biol Phys 1997; 37 (03) 523-529
    CrossrefPubMedGoogle Scholar
  • 9 Ramaswamy V, Remke M, Bouffet E. , et al. Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis. Lancet Oncol 2013; 14 (12) 1200-1207
    CrossrefPubMedGoogle Scholar
  • 10 Kumar S, Handa A, Jha DK, Choudhary A. Supratentorial metastasis of medulloblastoma in adults. Asian J Neurosurg 2016; 11 (03) 320
    Article in Thieme ConnectPubMedGoogle Scholar
  • 11 Gerlach R, Kieslich M, van de Nes J, Galow W, Seifert V. Supratentorial leptomeningeal metastasis of a medulloblastoma without cerebellar tumor recurrence. Acta Neurochir (Wien) 2002; 144 (02) 201-204 , discussion 204
    CrossrefPubMedGoogle Scholar
  • 12 Kondoff SI, Milev MD, Laleva LN. , et al. A case of early extraneural medulloblastoma metastases in a young adult. Asian J Neurosurg 2015; 10 (04) 331-333
    Article in Thieme ConnectPubMedGoogle Scholar
  • 13 Michalski J, Janss A, Vezina G. , et al. Results of COG ACNS0331: a phase III trial of involved-field radiotherapy (IFRT) and low dose Craniospinal irradiation (LD-CSI) with chemotherapy in average-risk Medulloblastoma: a report from the Children's oncology group. Int J Radiat Oncol Biol Phys 2016; 96 (05) 937-938
    CrossrefPubMedGoogle Scholar
  • 14 Rickert CH. Extraneural metastases of paediatric brain tumours. Acta Neuropathol 2003; 105 (04) 309-327
    CrossrefPubMedGoogle Scholar