Recent Applications of Continuous Flow in Homogeneous Palladium Catalysis

Abstract

Considerable advances have been made using continuous flow chemistry as an enabling tool in organic synthesis. Consequently, the number of articles reporting continuous flow methods has increased significantly in recent years. This review covers the progress achieved in homogeneous palladium catalysis using continuous flow conditions over the last five years, including C–C/C–N cross-coupling reactions, carbonylations and reductive/oxidative transformations.

1 Introduction

2 C–C Cross-Coupling Reactions

3 C–N Coupling Reactions

4 Carbonylation Reactions

5 Miscellaneous Reactions

6 Key to Schematic Symbols

7 Conclusion

Key words

flow chemistry - homogeneous catalysis - palladium - cross-coupling - Buchwald–Hartwig - carbonylation - oxidation - reduction

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