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Synthesis 2021; 53(06): 1103-1111
DOI: 10.1055/s-0040-1706473
DOI: 10.1055/s-0040-1706473
paper
Facile and Mild Access to Fluorescent Ladder-Type Indolo[3,2-a]carbazoles via Cascade Annulation
This project was supported by the National Key Research and Development Program of China (No. 2017YFE0102200) and Alzheimer’s & Aging Research Center, USA for Y. Yu; Zhejiang Provincial Natural Science Foundation of China (No. LY18H300001) and the Multiple Sclerosis National Research Institute, USA for W. Chen.
Abstract
A set of fluorescent ladder-type indolo[3,2-a]carbazoles were rationally developed via cascade annulation of indoles and nitroolefins under mild reaction conditions. Diverse functional groups were tolerated. Moreover, structure–photophysical properties relationships (SPPR) of indolo[3,2-a]carbazoles were observed to be simply tuned by changing the electronic nature of the peripheral substituents.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0040-1706473.
- Supporting Information
Publication History
Received: 30 July 2020
Accepted after revision: 26 August 2020
Article published online:
15 October 2020
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